3D ASL - XA31

Brain perfusion MRI can help us better understand an monitor. The metabolic and functional core lights of a stroke lesion both in the acute and chronic phase and beyond. The local tissue damage ASL. Arterial spin labeling ASL is an MRI brain perfusion technique. It allows repeated perfusion measurements and estimation of relative cerebral blood flow CBF over the whole brain without the need for exogenous contrast. When it comes to monitoring stroke patients, ASL can therefore provide useful information about the short term or long term. For example, chronic versus acute effects of pharmacological treatments. Or surgical interventions with respect to stroke onset. ASL uses the protons in arterial blood as an endogenous contrast agent to evaluate perfusion non invasively. This means a subtraction technique is used to cancel all static tissue signals. Only the blood signal remains. ASL is available as a 2D EPI sequence, two DSL and as a 3D graze sequence. 3D ASL both 2D and 3D sequences output. The qualitative perfusion weighted Maps and the relative cerebral blood flow Maps, which are the relatively quantitative evaluation of the brain profusion. Three DSL also supports multiple TI measurement with which a curved, fitted relative cerebral blood flow map. In a bolus arrival time map will be generated because of higher SNR and higher spatial resolution. Three DSL is preferred. In order to use the ASL sequences and the pseudo continuous arterial spin labeling option, you need the pseudo continuous arterial spin labeling and the ASL license in 3D ASL, additional licenses will be needed for the inline calculation of the multiple TI Maps. To start, the 3D ASL protocol, go to the dot cockpit under profusion. In the library, select the 3D ASL protocol. In the drop down menu you can select the profusion mode. Two perfusion modes are available for 3DS, L, Fair, Q2 T and pulsed arterial spin labeling and pseudo continuous arterial spin labeling. In either mode, the inline calculation of relative cerebral blood flow is performed. With regard to signal to noise ratio, SNR and contrast to noise ratio, SNR pseudo continuous arterial spin labeling is recommended. Additionally, you can select the background suppression in the dropdown menu. The signals of static tissues are suppressed and the SNR of profusion signals is higher grey, white strong is recommended for better suppression, but with an increased specific absorption rate value. For pseudo continuous arterial spin labeling protocols, the guidance view can help you to place the labeling plane in the correct position above the carotid artery bifurcation and below the V3 segment.

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