ADVIA Centaur® CP Immunoassay System Quality Control Online Training

Welcome to the ADVIA Centaur® CP Quality Control Online Training course. The procedures covered in this course include: The quality control features of the ADVIA Centaur® CP system Processing QC samples Reviewing and managing QC data   Select Next to continue. Describe how to define controls Describe how to review QC data Explain how to schedule QC List the steps to create a test profile List the steps to edit a QC definition Upon successful completion of this course, you will be able to: Select Next to continue. Congratulations. You have completed the ADVIA Centaur CP Quality Control Online Training Course. Listed below are the key points that have been presented. Take time to review the material as needed before proceeding to the final quiz.   Describe How to Define QC: Access the Definition window and select the Controls tab. Select Add and enter control details. Select an assay, enter the expected values and select Add. Select Save. List the Steps to Edit a QC Definition: Access the Definition window and select the Controls tab. Select the control to be edited and select Details. Select the assay to be edited and change the expected values. Select Save on the left side of the window. Select Save on the right side of the window. Explain How to Schedule QC: Schedule with barcodes:  Load QC rack and select the Sample Compartment on the workspace.  Select the rack, level of QC and test or profiles to be processed. Schedule without barcodes:  Load QC rack and select the Sample Compartment on the workspace.  Select the rack, white box where QC sample is positioned and manually enter the control ID.  Select tests or profiles to be processed. Schedule on multiple reagent lots or packs: Load QC rack and select the Primary Reagent Compartment on the workspace.  Select reagent pack, select the Run Controls button and press OK.  List the Steps to Create a Test Profile: Select the Setup task button and Profile Definition tab. Select Add Profile. Enter the name, select tests and press Save. Describe How to Review QC Data: Open the Quality Control tab in Results.  Any QC result that was out of range will be flagged with a yellow status symbol. Select the control result and press Details to review the expected range for that assay. Export results from the Quality Control tab in Results.  Select Export, choose criteria and select OK. Print control results by selecting the Print button, choosing criteria and report type and selecting OK. Select Next to continue. Quality Control Definition: Enter and edit QC ranges using the Definition task button 50 tests per control can be defined 300 controls can be defined Note: It is recommended that you evaluate each new lot of QC material before placing it into routine use. Define a control Learn about defining a control. Checklist TitleChecklist TypeChecklist ContentAccess the Definition WindowHTML Select Definition from the Task bar. Select each checkbox to learn more about defining QC.Select Controls TabHTML Select the Controls tab. The Controls tab displays a list of controls which have been previously defined.Select AddHTML Select the Add button.Enter Control DetailsHTML Enter the name of the control. Select the Type of control.  Routine is already selected as the default.  This can be changed to Kit if the assay controls are packaged with the reagent as a kit. Enter the lot number and expiration date.  The expiration date can be manually typed or selected from the drop-down calendar.Select Usage and Control BarcodeHTML On the right side of the screen is the Usage area.  This refers to how this control will be used. Primary refers to a control that is currently in use Parallel is typically used when a new control is being run concurrently with the current or primary control Alternate is used when you need to run other controls, typically during troubleshooting Enter the level of control - 1,2,3 or 4. The Control Barcode field is filled in automatically when the lot number is entered.  If the barcode you will be using to process controls is different, you can edit it now. The Pool field is used to enter an identification number when using patient pools created in your laboratory.Select Assay and Enter ValuesHTML Select an assay from the list on the right side of the window.  If you do not see the assay, use the single or double arrows to scroll through the assay list. Enter the expected values - mean and 2SD or low and high ranges.  You can use the QC material product insert ranges or your established laboratory ranges.  Enter the number of replicates and select Add. Repeat these steps for the remaining assays you will process on this level of control.Select SaveHTML When all of the assays have been added to the Values table, select the Save on the right side of the screen. The Controls screen displays with the new QC definition added.  When finished adding controls, select Close. When complete, select the X in the upper-right corner to close the window and continue.   Practice Defining QC Practice defining QC. Instructions:If media does not automatically start, select the play arrow to begin.Flash File:/content/generator/Course_90004424/sim_CP_CreateQCDefinition800x600_9_2/sim_CP_CreateQCDefinition800x600_9.swfHTML5 File:/content/generator/Course_90004424/sim_CP_CreateQCDefinition800x600_9_2/index.htmlPDF File: Laboratory Policy or the addition of a new assay may be causes for QC definitions to be edited. There are several steps for editing the control definition.   1.  Select Definition & Controls tab, then Control. 2.  Select the Details button and the assay. 3.  Edit ranges and select Save. Edit a control definition Learn about how to edit a control definition in the software. Checklist TitleChecklist TypeChecklist ContentSelect Definition & Controls TabHTML Select the Definition task button and then select the Controls tab. Select each checkbox to learn more about editing a control definition.Select ControlHTML Select the Control that requires editing and press the Details button.Select AssayHTML Select the assay that requires editing from the Values table of the left.Edit RangesHTML Edit either the high and low ranges or the mean and two standard deviations. Changing either set of values automatically adjusts and calculates the other set. Select Save on the left side of the screen to save changes to the assay.Select SaveHTML Select Save on the right side of the window to save the changes to the QC definition. When complete, select the X in the upper-right corner to close the window and continue. Schedule QC: In the Sample Compartment or Primary Reagent window With and without barcodes On multiple reagent lots and packs Two level of QC must be processed for each assay on each day that samples are analyzed. QC samples must also be processed when a two-point calibration is performed.   Scheduling a QC Sample Learn about Scheduling a QC sample with barcodes. Checklist TitleChecklist TypeChecklist ContentLoad QC SamplesHTML Load the rack of QC material into the sample compartment. Select each checkbox to learn more about Scheduling a QC sample with barcodes.Select Sample CompartmentHTML From the workspace, select the Sample Compartment screen to schedule the QC run.Select Sample RackHTML In the Sample Compartment Selection area, select the rack containing the QC material. Select Control IDHTML Select the control ID.Select Profile or AssaysHTML Select the test(s) to be run on the control.  Choose from previously defined profiles, individual assays or both.Select CloseHTML When you have selected all of the assays for that control, you may continue by scheduling another control or select Close to return to the workspace.Select StartHTML If the system is in the Ready state, select Start from the task bar to begin processing your run. When complete, select the X in the upper-right corner to close the window and continue. Schedule QC without barcodes Learn about Scheduling a QC sample without barcodes. Checklist TitleChecklist TypeChecklist ContentLoad QC SamplesHTML Load the rack of QC material into the sample compartment. Select each checkbox to learn more about Scheduling a QC sample without barcodes.Select Sample CompartmentHTML From the workspace, select the Sample Compartment screen to schedule to QC run.Select Sample RackHTML In the Sample Compartment Selection area, select the rack containing the QC material. Note the white boxes in the positions where the non-barcoded QC samples are loaded.Enter Control IDHTML Select each white box and enter the Control ID.  As soon as you enter an ID that the system recognizes as a control, the smp box changes to ctrl. Note:  If you are not sure what the control ID is, check the Controls tab in Definition.Select Profile or AssaysHTML Select the tests to be run on the control.  Choose from previously defined profiles, individual assays or both. When you have selected all of the assays for each control, select Close to return to the workspace.Select StartHTML If the system is in the Ready state, select Start to begin processing your run. When complete, select the X in the upper-right corner to close the window and continue. Schedule QC on multiple packs Learn about Scheduling QC on multiple reagent lots and packs. Checklist TitleChecklist TypeChecklist ContentLoad QC SamplesHTML Load the rack of QC material into the sample compartment. Select each checkbox to learn more about Scheduling QC on multiple reagent lots and packs.Select Primary Reagent CompartmentHTML From the workspace, select the Primary Reagent Compartment.Select PackHTML Select the reagent pack you want to use to process QC.Select Run ControlHTML Select the Run Control button.Select OKHTML The system displays the Matching Controls screen which displays a list of the Name, Lot, Expiration Date, Barcode ID, Type, Assay and Use now. In the Use now column, a checkmark indicates the control that will be run.  All valid controls that are onboard are automatically checked.  You must uncheck a control in the list if you do not want it to run. Select OK.  The system will initialize and then begin processing the scheduled QC.Select Another PackHTML If you want to run a control on a different lot number, select the reagent pack and repeat the previous steps. This can also be performed if you want to schedule controls on multiple packs of the same lot number. When complete, select the X in the upper-right corner to close the window and continue. There are several steps for reviewing and managing QC results. They are:   1.  Select Results 2.  Select Quality Control 3.  Manage Results 4.  Select a Control ID 5.  Select the Details button 6.  Select Close   Reviewing & Managing QC Results Learn how to review QC results. Slide NumberText BlocksCalloutsAudio ScriptImage File1 Select Results   To access the quality control data, select Results at the workspace. Select Next to continue.     Note: If audio does not automatically start, select the play arrow in the top left to begin.To access the quality control data, select Results at the workspace.2Select Quality Control Next, select the Quality Control tab.  This screen displays a list of QC samples and provides information about: Controls run. Assays run on the controls. Date and time. Result, RLU and any flags that were generated. Select Next to continue.    Next, select the Quality Control tab. This screen displays a list of QC samples. It provides information about the controls that were run, the assays that were run on the controls, the date and time, the result, the RLU and any flags that were generated.3Select a Control result and select the Details button. Select Next to continue.   Select a control result.4The Quality Control Details window appears. The top section displays the control information, including the range and mean for that lot of control. The bottom left-hand corner shows the control results for the specific assay. Select Next to continue.    Select the Details button. The Quality Control Details window appears. - The top section displays the control information, including the range and mean for that lot of control. - The bottom left-hand corner shows the control results for the specific assay. 5Select CloseOnce you have completed the review, select the Close button in the Quality Control Details window to return to the Quality Control tab.  When complete, select the X in the upper right corner to close the window and continue.Once you have completed the review, click the Close button in the Quality Control Details window to return to the Quality Control tab. Print QC records: 1.  Select the records. 2.  Select print. 3.  Choose report type. 4.  Select OK. Printing QC Records Learn about printing QC records. Checklist TitleChecklist TypeChecklist ContentSelect RecordsHTML Select the control results that need to be printed and press the Print button. Select each checkbox to learn more about Printing QC Records.Select ReportHTML Select the Quality Control Summary or Quality Control Details report. Quality Control Summary lists each control SID, Control Name, Assay, Result Date, Result, Flags, QC Status. QC Status is OK or >=SD. Quality Control Details contains everything in the Summary report plus the defined range and mean, control lot number, and replicate results.Select OKHTML Then select OK to print the selected records. The window will automatically close when the printing job has been sent to the printer. When complete, select the X in the upper-right corner to close the window and continue.   The Export button can be used to maintain quality control records. The steps to perform the export function are:   1.  Select the records 2.  Select export 3.  Choose criteria and location 4.  Select OK Exporting QC Records. Learn about Exporting QC Records. Checklist TitleChecklist TypeChecklist ContentSelect RecordsHTML Select the Control record or records to be exported.  Select the Export button. Select each checkbox to learn more about Exporting QC records.Select CriteriaHTML Choose the selection criteria.Select File LocationHTML Select the File Location button.Select LocationHTML Select the Save in drop-down menu and select file location. Enter Name of FileHTML Enter the name of the file including the file extension .ttx.  Select Save.Select OKHTML Select OK.Select NextHTML If you chose to export to a CD, a CD Writing Wizard window will appear.  Select Next to complete the export. When complete, select the X in the upper right corner to close the window and continue. The Beads and Reagents Onboard screen provides detailed information about the reagents and beads onboard the instrument.  You are able to view test name, kit lot, bead or reagent lot, tests left, kit expiration date, use by date, last adjustment date, adjustment due date, and carousel position.  This log may be printed for your records or for troubleshooting.  Select the link below to learn more about the Beads and Reagents Onboard screen. QC Test Profiles: Allow you to schedule multiple tests for a QC sample Are defined in the Setup window Defining a Test Profile Learn how to define a QC test profile. Checklist TitleChecklist TypeChecklist ContentSelect SetupHTML From the workspace, select Setup from the task bar. Select each checkbox to learn more about defining a QC test profile.Select Profile DefinitionHTML Select the Profile Definition tab.Select Add ProfileHTML Select the Add Profile button.Enter Profile InformationHTML Enter a profile and LIS name.  Select the assays to be included in the profile.Select SaveHTML Select Save. When complete, select the X in the upper-right corner to close the window and continue. Practice Defining profile Practice defining a QC test profile. Instructions:If media does not automatically start, select the play arrow to begin.Flash File:/content/generator/Course_90004424/sim_CP_QCTestProfile800x600_9/sim_CP_QCTestProfile800x600_9.swfHTML5 File:/content/generator/Course_90004424/sim_CP_QCTestProfile800x600_9/index.htmlPDF File: