ADVIA Centaur® XP Immunoassay System EHIV Online Training

Welcome to the ADVIA Centaur® XP Immunoassay System EHIV Online Training course. The EHIV assay is processed differently than other assays on the instrument.  It is important to understand what these differences are to ensure EHIV processing in your lab runs smoothly. Note: This course is only for FDA regulated facilities. Select Next to continue. Define, schedule, and run QC Describe how to schedule patients and review results Identify common issues List the requirements for Control Bracketing List the steps to schedule and run a calibration Upon successful completion of this course, you will be able to: Select Next to continue. Welcome to the ADVIA Chemistry XPT System Positioning and Messaging Online Training course. In this course you will learn the messaging, positioning and strategy developed by Global Solutions marketing to help you better position the ADVIA Chemistry XPT System to the targeted customer. The features, advantages and values, and the ADVIA Chemistry portfolio comparison will give you a quick summary of some key points about the ADVIA Chemistry XPT System and its predecessors.  Once you have learned what you need to know about the ADVIA Chemistry XPT System, you'll want to know more about your customer. You'll learn how to identify the targeted customer and also how to segment customers based on their purchasing behavior. This information will help you to be sure you have the right message for the right audience.  Select next to review the course objectives.  Congratulations.  You have completed the ADVIA Centaur® XP Immunoassay System EHIV online training course.  Listed below are the key points that have been presented.  Take time to review the material before you proceed to the final quiz.  List the requirements for Control Bracketing EHIV requires you to begin and end a group of patient samples with a specific set of controls. The opening bracket controls allow processing of the samples and the closing bracket controls release the retained results for those samples.  The controls are located in the reagent box. List the steps to schedule and run a calibration If necessary, scan in the Master Curve and Calibrator Definition cards.  Schedule the calibration in the Worklist Schedule window and then place the calibrators on the system. List the steps to define, schedule and run QC Quality control is defined in the Control Definition window.  QC ranges can be found on the Expected Values card which is located in the EHIV reagent box.  Enter the information of the Control Definition window exactly as it appears on the card. QC can be ordered in the Worklist Schedule window.  Place the controls on the system and make sure all levels have been aspirated before placing patient samples on the system. Describe how to schedule patients and review results Patients can be scheduled by the LIS or in the Worklist Schedule window.  Samples can be placed on the system after the opening bracket controls have been aspirated. Patient results will not be displayed until the closing bracket controls have been processed.  The closing bracket can be ordered in the Worklist Schedule or Worklist Summary window. Identify common issues A No Bracket message will appear if patient samples are placed on the system before the opening bracket controls have been aspirated. Results will be discarded if any level of the closing bracket QC is out of range, the bracket is open for 24 hours or a calibration is process. Select Next to continue.   Control Bracketing: Run a control set before and after patient samples. Included in EHIV kit: ReadyPack primary reagent Master Curve and Calibrator definition cards Low and high calibrators Controls NEG HIV control POS control for HIV-1 POS control for HIV-1, Group “0” POS control for HIV-2 Expected control values card Select Next to continue. Welcome to the ADVIA® Chemistry XPT System Needs Based Demo. The intent of this video based demo and script is to provide a guide to help you prepare a ADVIA® Chemistry XPT System customer needs based demo.  It is not meant to be used as a script to be memorized. The video and video script will help you to prepare your own Needs-Based Demo, based on the specific needs expressed by your customer in previous interactions. Select the links below to view the video and download a printable copy of the sample demo script.  Schedule and run a calibration: Scan Master Curve and Calibrator Definition cards Schedule calibration Calibration interval is 14 days Calibration Learn about processing an EHIV calibration. Checklist TitleChecklist TypeChecklist ContentScan Master Curve CardHTML   Select the Calibration menu and select Master Curve Definition.  Press the Scan Data button and use the handheld barcode scanner to scan the card top to bottom.  Select Save. Select each checkbox to learn more about processing a calibration.  Scan Calibrator Definition CardHTML   From the Calibration menu, select Calibrator Definition. Press the Scan Data button and scan the card from top to bottom.  Select Save.  Schedule CalibratorHTML   From the Worklist Schedule window, select the Calibrator radio button.  Select EHIV and the appropriate calibrator lot.  Press Save.  Process CalibratorsHTML   Place the high and low calibrators onto the system. When the calibration is complete, the status should be Valid.  In order to see the Valid flag, select the Conc dropdown menu and select Index. When complete, select the X in the upper-right corner to close the window and continue.   Customers are categorized according to the five customer segments defined by Global Customer Segmentation. Global Customer Segmentation enables you to position products based on the values, perspective and expectations defined for each customer segment. The chart displayed here provides the general, non product specific Global Customer Segmentation categories.  Select the link below to learn about the Global Customer Segmentation categories developed specifically for the Centaur XPT. EHIV QC Defining EHIV controls is performed in the Control Definition window. Control information is located on the Expected Value card found in the EHIV reagent box. Four controls: NEG HIV control POS control for HIV-1 POS control for HIV-1, Group “0” POS control for HIV-2 Note: Controls must be processed before and after patient samples.   Quality Control Learn about processing QC for EHIV testing. Slide NumberText BlocksCalloutsAudio ScriptImage File1 Quality Control Expected Value cards Negative control Positive controls: HIV-1, HIV-2, HIV-1 Group "O" Select Next to continue. Note: If audio does not automatically start, select the play arrow in the top left to begin.Obtain the Expected Value cards from the kit of EHIV you will be using. There are four levels of control. One negative control and three positive - HIV type 1, HIV type 1 group O, HIV type 2. The information needed to enter a quality control definition is located on these cards. The checksum value is unique to EHIV controls. Select next to continue.2 Defining QC Enter name exactly as it appears on the card Lot number Expiration date Checksum Assay and range Select Next to continue.    Access the Control Definition window from the Quality Control menu. Select the Add button at the bottom of the window. Enter the QC information exactly as displayed on the QC label and then press Save. Select next to continue.3 Schedule the opening bracket QC Select Control from Worklist Schedule Select EHIV Choose correct levels of QC Press Save Select Next to continue.    From the Worklist menu, select Schedule. Choose the Control radio button and select EHIV and the appropriate levels of QC. Press Save. Select next to continue.4 QC results If opening bracket QC is within range, the bracket will remain open for 24 hours.   When complete, select the X in the upper-right corner to close the window and continue.If all of the levels of QC are within range, the instrument will consider this QC the open bracket. The instrument will run all EHIV patient samples but will not display results until the end bracket controls have completed successfully. The bracket will remain open for 24 hours. Define Quality Control Practice defining EHIV controls. Instructions:If media does not automatically start, select the play arrow to begin.Flash File:/content/generator/Course_90004079/sim_CXP_DefineEHIV_training_9/sim_CXP_DefineEHIV_training_9.swfHTML5 File:/content/generator/Course_90004079/sim_CXP_DefineEHIV_training_9/index.htmlPDF File: Patient processing: Patient samples can be scheduled using the LIS or manually by SID or barcode. The opening bracket QC must be in process or complete before patient samples are placed on the system. When patients are complete, they are flagged with a Waiting for Control symbol. Patient results will not be posted to the Worklist Summary until the closing bracket controls have been processed. Processing Patients Learn about processing patients. Checklist TitleChecklist TypeChecklist ContentSchedule PatientsHTML   Your LIS can be used to order EHIV for patient samples. If necessary, you can manually order patients in the Worklist Schedule window.  You must schedule by SID. Select each checkbox to learn more about patient processing.  Process SamplesHTML   After the opening bracket controls have been aspirated, you may place the samples on the system.   Review Worklist SummaryHTML   When the patient samples have finished processing, a Waiting for Control symbol will appear on the Worklist Summary next to each order.  This means that the instrument will not display a result for the patient until the closing bracket controls have been processed. When complete, select the X in the upper-right corner to close the window and continue.   Closing Bracket Learn about the closing bracket. Checklist TitleChecklist TypeChecklist ContentOrder in Worklist ScheduleHTML   Worklist Schedule Closing bracket controls can be ordered from the Worklist Schedule or Worklist Summary window.  When you are ordering from the Worklist Schedule window, symbols will appear next to the lots of QC that were used to open the bracket.  These symbols will only appear if the opening bracket has successfully completed.  The same lot of QC must be used for the opening and closing brackets. Select each checkbox to learn more about the closing bracket.  Order in Worklist SummaryHTML   Worklist Summary To order the closing bracket from the Worklist Summary window, select any EHIV patient sample that has finished processing.  Select the Close Set button and the system will automatically schedule controls for the same lot that was used to open the bracket.  Observe Control ReminderHTML   Alerts - 9 hours If the closing bracket controls have not been processed within 9 hours of the opening bracket controls, the Event Log will display a Control Reminder. This warning will not impact any results.  Observe Control WarningHTML   Alerts - 20 hours If the closing bracket controls have not been processed 20 hours after the opening bracket controls, the Event Log will display a Control Warning. This error does not impact any results, but the closing bracket should be processed as soon as possible.  Review ResultsHTML   Results After the closing bracket controls have successfully completed, patient results will be displayed. To view the actual result, select the Conc dropdown menu and select Index. When complete, select the X in the upper-right corner to close the window and continue.   You have just learned about processing the closing bracket. Now let's practice what you have learned. Your Turn Practice scheduling the closing bracket. Instructions:If media does not automatically start, select the play arrow to begin.Flash File:/content/generator/Course_90004079/sim_CXP_SchedClosing_training_9/sim_CXP_SchedClosing_training_9.swfHTML5 File:/content/generator/Course_90004079/sim_CXP_SchedClosing_training_9/index.htmlPDF File: The most common errors that occur during EHIV processing: No Bracket - patient samples placed on the instrument before the opening bracket QC Discarded Results - closing bracket QC out of range, bracket open for 24 hours or calibrated while bracket still open Common Errors Learn about common errors. Tab TitleTextNo Bracket If patient samples are placed on the instrument before the open bracket has finished aspirating, a No Bracket message will appear in the Sample Status window.  To resolve this issue, remove patient samples and wait for the opening bracket to complete.    Results Discarded If the closing bracket QC is out of range, all patient results are not reported.  These samples will be found in the Results Discarded view of the Worklist Summary.  Note the trashcan symbol next to each sample. To resolve this issue, locate the samples, reschedule and place on the system again. When complete, select the X in the upper-right corner to close the window and continue.