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Atellica® CH Analyzer Hardware Overview PEP to Go

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SIEMENS Healthineers Atellica® CH Analyzer Hardware Overview PEP to Go Template Effective Date: 05/27/2019 | HOOD05162003010284 1 Effective Date: 8/13/2019 | HOOD05162003028269 Unrestricted © Siemens Healthcare GmbH, 2018 Atellica® CH Analyzer SIEMENS Hardware Overview Healthineers Exterior Components – Front A. System front cover – controlled by interlocks. Operator can unlock using a button in the software B. System fluid drawer – used to house and replace the CH Diluent, CH Wash, CH A Conditioner and CH Cleaner bottles. Operator can access anytime C. Water and liquid waste – contains one reservoir for water and two reservoirs for waste D E D. IMT (integrated multisensor technology) fluids – used to house and replace the IMT Std B+Salt Bridge, IMT Standard A and IMT Diluent bottles G F E. Reagent tray lid – used to load reagent packs and remove reagent packs. Operator can access anytime F. Module display – used to load and unload supplies and reagents. *Only found in Sample Handler configurations G. Atellica Magline® Transport – transports samples between the sample handler and the analyzers. *Only found in Sample Handler configurations B C NOTE: Do not position pacemakers or other implanted medical devices closer than 7.5 cm (3 inches) from the Atellica Magline® Transport. Carriers on the Atellica Magline Transport generate strong magnetic fields that can interfere with cardiac medical implants. 2 IM Effective Date: 8/13/2019 | HOOD05162003028269 Hardware Overview Unrestricted © Siemens Healthcare GmbH, 2019 Atellica® CH Analyzer SIEMENS Hardware Overview Healthineers Interior Components – Front Dilution probe – transfers sample from sample tube to either the IMT system or E A. the dilution ring. Has clot detection, crash protection, and liquid surface A verification B. Dilution ring – holds the dilution cuvettes which house the diluted samples. The diluted sample is held for retest until that cuvette reaches the dilution washer (typically at least 10 minutes) C. Dilution mixer – stirs the diluted sample that has been transferred to the dilution F cuvette D. Dilution washer – washes the cuvettes after a sample is processed so the cuvettes can be reused E. Sample probe – transfers an aliquot of diluted sample from dilution cuvette to reaction cuvette. Has clot detection, crash protection, and liquid surface verification D F. IMT system – uses potentiometry to determine the concentration of sodium, C potassium and chloride ions in patient samples A B Close up of upper left area of above image – Dilution ring area 3 Effective Date: 8/13/2019 | HOOD05162003028269 Unrestricted © Siemens Healthcare GmbH, 2019 Atellica® CH Analyzer SIEMENS Hardware Overview Healthineers Interior Components – Front (continued) A. Reaction ring – processes photometric assays in reaction cuvettes B. Reagent probe 1 and 2 – transfers reagent from reagent packs in the reagent E H compartment into reaction cuvettes B C. Sample mixer – mixes together the first reagent and the diluted sample in the reaction cuvette D. Reagent mixer – mixes the diluted sample and both reagents in the reaction A F cuvette D E. Reaction washer – washes the reaction cuvettes after a sample has been B processed so the cuvettes can be reused Reagent compartment – has 2 refrigerated reagent servers (1 and 2). Each server C F. holds 24 reagent packs in the inner ring and up to 46 in the outer ring for a total of 70 packs (3 of the positions are reserved for reagent probe cleaners) G G. Reagent tray – used to load reagents on the system. Holds up to six reagent packs at a time H. Reagent loader – scans new reagent packs and transports them from the reagent tray to the reagent compartment 4 Effective Date: 8/13/2019 | HOOD05162003028269 Unrestricted © Siemens Healthcare GmbH, 2019 Atellica® CH Analyzer SIEMENS Hardware Overview Healthineers Exterior Components – Back A A. System back cover – controlled by interlocks. Operator can unlock using a button in the software B B. Photometer – consists of a light source and a detection assembly, which are mounted across from each other on the reaction ring. The photometer measures the light absorbance of samples as they pass in between the light source and the detection assembly. These absorbances are then converted to results that are reported on the system. (* The photometer is located under the cover in the area C C indicated in the image) C. Fan filters – There are three fans located on the CH analyzer. One on the left rear D panel, one in the center rear panel and one on the front left door. Each fan has a filter in front of it D. Main power switch – used to power off and on the analyzer C 5 Effective Date: 8/13/2019 | HOOD05162003028269 Unrestricted © Siemens Healthcare GmbH, 2019 Atellica® CH Analyzer SIEMENS Hardware Overview Healthineers Photometric Test Processing Sequence 1. Diluted sample is transferred into a dilution cuvette on the dilution ring, and then mixed 2. The first reagent is transferred into a reaction cuvette on the reaction Reaction Ring ring 3. An aliquot of diluted sample is transferred into the reaction cuvette containing the first reagent. The remaining diluted sample in the dilution cuvette can be used for additional tests on an order 4. The first reagent and diluted sample are mixed 5. The second reagent is transferred into the reaction cuvette containing the first reagent and the diluted sample 6. The diluted sample and both reagents are mixed Dilution Ring Reagent Probes 7. The reaction takes place for the amount of time designated for the assay. The analyzer allots approximately 10 minutes of incubation time from the start of the sample addition 8. The absorbance data is read by the photometer which is read every 9 seconds 6 Effective Date: 8/13/2019 | HOOD05162003028269 Unrestricted © Siemens Healthcare GmbH, 2019 Atellica® CH Analyzer SIEMENS Hardware Overview Healthineers IMT Test Processing Sequence 1. Standard A solution is pulled through the IMT cartridge 2. The potential difference is measured between each of the 3 analytes in the Standard A solution and the reference electrode 3. Air and fluidic segments of Standard A are pulled into the IMT cartridge to both clean and prepare the sensor chip for sample measurement 4. The IMT diluent pump dispenses 75 µL of IMT diluent into the IMT sample port 5. The dilution probe aspirates 25 µL of sample from a sample container 6. The dilution probe dispenses the sample and 150 µL of special reagent water into the IMT port 7. The dilution probe returns to its wash station for rinsing and cleaning *This procedure is continued on the next slide 7 Effective Date: 8/13/2019 | HOOD05162003028269 Unrestricted © Siemens Healthcare GmbH, 2019 Atellica® CH Analyzer SIEMENS Hardware Overview Healthineers IMT Test Processing Sequence (continued) 8. The analyzer pulls the mixed sample through the IMT cartridge 9. The system measures the potential difference between each of the three analytes in the sample and the reference electrode 10. The drift correction completes when the analyzer pulls a second Standard A sequence though the IMT cartridge, comparing this reading to the reading in step 2 11. The system converts the potential differences into ion concentrations and reports this value 8 Effective Date: 8/13/2019 | HOOD05162003028269 Unrestricted © Siemens Healthcare GmbH, 2019 SIEMENS Healthineers Please note that the learning material is for training purposes only! For the proper use of the software or hardware, please always use the Operator Manual or Instructions for Use (hereinafter collectively “Operator Manual”) issued by Siemens Healthineers. This material is to be used as training material only and shall by no means substitute the Operator Manual. Any material used in this training will not be updated on a regular basis and does not necessarily reflect the latest version of the software and hardware available at the time of the training. The Operator's Manual shall be used as your main reference, in particular for relevant safety information like warnings and cautions. Note: Some functions shown in this material are optional and might not be part of your system. Certain products, product related claims or functionalities (hereinafter collectively “Functionality”) may not (yet) be commercially available in your country. Due to regulatory requirements, the future availability of said Functionalities in any specific country is not guaranteed. Please contact your local Siemens Healthineers sales representative for the most current information. The reproduction, transmission or distribution of this training or its contents is not permitted without express written authority. Offenders will be liable for damages. All names and data of patients, parameters and configuration dependent designations are fictional and examples only. All rights, including rights created by patent grant or registration of a utility model or design, are reserved. Atellica, and all associated marks are trademarks of Siemens Healthcare Diagnostics Inc. or its affiliates. All other trademarks and brands are the property of their respective owners. Product availability varies by country and is subject to varying regulatory requirements. Please contact your local representative for availability. Copyright © Siemens Healthcare GmbH 2019 Global Siemens Healthineers Headquarters Henkestr. 127 91052 Erlangen, Germany Phone: +49 9131 84 0 siemens.com/healthineers 9 Effective Date: 8/13/2019 | HOOD05162003028269 Unrestricted © Siemens Healthcare GmbH, 2019