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Cross Calibration mMR Biograph - E11P

This Job Aid provides workflow to perform a PET cross calibration procedure to calibrate the mMR Biograph to a specific dose.

Cross Calibration mMR Biograph – E11P Software Cross Calibration mMR Biograph – E11P Software PET Scanner Cross Calibration is a procedure that calibrates the mMR Biograph to a specific dose. Cross Calibration Requirements 1. The procedure must be repeated as soon as a. A different (for example new) dose calibrator is used. b. A new calibration probe is used. c. Whenever the mMR 68-Ge Daily QC Phantom is replaced. Prerequisites 1. mMR Water Cylinder Phantom a. Filled with water and 60 MBq (+/-10 MBq) of 18-FDG. b. Calibrated to Start of Cross Calibration measurement. MR 2. mMR Biograph Uniform Phantom (daily QC phantom). 3. Excel worksheet to calculate Cross Calibration factor. (e.g., worksheet is on a CD delivered with the user manuals). 4. Computer with MS Excel installed to execute Cross Calibration spread sheet. 5. mMR Biograph Clock and calibrated dose calibrator must have the same date and time. Unrestricted 0 Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2020 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 09/03/2020 | HOOD05162003124365 Healthineers Job Aid | Cross Calibration mMR Biograph – E11P Effective Date: 09/03/2020 | HOOD05162003124365 Measurement 1. Perform a PET Daily QC measurement with: a. Setup Enabled Selected. b. Enter a Cross Calibration Factor of 1.00. e Siemens Med Service Software - Windows Internet Explorer provided by Si ... PET Normalisation Assay Data Setup Enable Setup The last successful PET setup has been performed on 2016-06-20113:41:55Z, which is more than 7 days ago: is recommended to perform the Setup at least every 7 days. Flease bck the Setup box above to insboate a.new PET setup for this normalization Phantom Settings Volume 9425 (ml) Isotope Ge-68v Activity 101.16 MBq Date/Time 2016 - Mar -23 08 00 Cross Calibration 1.00 Acquisition Scan duration 200 (MCounts) OK Cancel Unrestricted 0 Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2020 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 09/03/2020 | HOOD05162003124365 Healthineers Page 2 of 9 Job Aid | Cross Calibration mMR Biograph – E11P Effective Date: 09/03/2020 | HOOD05162003124365 2. Perform a Water Phantom Scan a. Ensure mMR Biograph Water Cylinder is filled with the required radioactivity. i. 60 Mbq (1.6 mCi) +/-10 Mbq (0.27 mCi) of 18-FDG. ii. Calibrated for Start of mMR Water Cylinder scan. b. Prepare mMR Water Cylinder. c. Mount Phantom at lowest position. 3. Open Customer Quality Assurance > Main Menu > OPTION > SERVICE > Customer QA. a. Customer Quality Assurance Window > select PET Phantom Positioning check box. b. Select mMR Water Cylinder Workflow – ensure phantom is moving into gantry. IT Coil Check ToDo IT PET Quality Check and Normalization ToDo PET Phantom Positioning Customer Running Siemens Med Service Software - Windows 1 ... [x] PET Phantom Positioning Phantom Setup Daily QC Customer (absolute) ACRIN ACR PET 1bed ACRIN ACR PET 2bed ACRIN Cylinder 1bed ACRIN Cylinder 2bed Daily QC Customer (absolute) Daily QC TuneUp (lightmarked) NEMA 10 PET Alignment (TuneUp) Water Unrestricted 0 Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2020 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 09/03/2020 | HOOD05162003124365 Healthineers Page 3 of 9 Job Aid | Cross Calibration mMR Biograph – E11P Effective Date: 09/03/2020 | HOOD05162003124365 4. Register a Patient a. Patient Name – use a meaningful description (e.g., Cross Calibration) b. Patient Position – select Head First – Supine c. Weight – enter weight of water inside phantom (9.45 kg/20.84 lbs.) d. Study – open Dot Cockpit create a PET Acquisition Protocol i. Don’t use a NEMA Program e. Don’t use a Localizer – use only the basic MR-PET group i. PET Planning ii. PetAcquisition iii. MRAC iv. Note: Localizer image might reduce to move the PET FoV in the GSP, this results in a mismatch between the PET and the UMAP!!! Important Notes: Dont use a NEMA Program Dont use a Localizer EXPLORER Edit Simulate ImStandard USER > User Testing . CrossCalibration > Cross Calibration x BIUMSE Search localizer LISER PET Planning @ PET Plan PelAcquisition 01:00 MRPETEMOCO Pesch MRAC_DIXON 00:29 New Region APPL Unrestricted 0 Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2020 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 09/03/2020 | HOOD05162003124365 Healthineers Page 4 of 9 Job Aid | Cross Calibration mMR Biograph – E11P Effective Date: 09/03/2020 | HOOD05162003124365 5. Open PET Planning Step – in queue and check the following parameters Pharmaceutical F-18 Solution Isotope F-18 Injection Unit Select the unit used for the activity Injection Dose Enter the actual dose injected into the water phantom Injection Date Enter the date and exact time when the activity was assayed Norm Valid Check Scan Mode Sinogram Scan Duration Unit Count Based Scan Duration /bed 100.000.000 counts Scan Direction Craniocaudal CrossCalib, Test 7/1/2006 Dot X PET Examination Planning Tracer Planning Coils 1 % PET Planning Last Calibration Date 7/1/2016 2 % PetAcquisition 06:00 Norm Valid V Isotope F-18 3 NEMA_Image_Quality 00:14 Pharmaceutical F-18-Solut .. Injection Dose 0.0 [MBq] Injection Date 7/1/2016 - Injection Time 8:34:04 AM: PET 00:00 2 06:00 E 00:14 K E Unrestricted 0 Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2020 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 09/03/2020 | HOOD05162003124365 Healthineers Page 5 of 9 Job Aid | Cross Calibration mMR Biograph – E11P Effective Date: 09/03/2020 | HOOD05162003124365 6. PET Acquisition and MRAC choose mMR Water Cylinder a. Note: If MR preparation fails, this must be done manually according to the syngo MR E11 documentation, chapter 3.6 Crise Calibration XV/10/1965 TA 10H . PM FIX Voel Diee 2 3x2 3:5.0mm Rel SR 1,00 V EScan Becon Pharons Phantom 2 PET Planning 2 Compartment NEMA Stattor Szan 4 %. MRAC DINON Phantom MMR Water Cyll Cross Castrabon 30/10/1955 Dor TA: 022 PM: FIX AT OT X V Riesclullen System Inine Common Notion Compensation Phantom Pramom Phantom_PetAcquisnon 2 Compartment NEMA Scatles Scan 3: PET PanING Plustom MUR Water Cy. 56 MBAC CDXION 7. Open PET ACQ Step and select Reconstruction Parameters under Recon > Common and Recon > Filter Parameter Card a. Iterations = 3 b. Image Matrix = 344 TA: 6:00 PM: FIX c. Filter = Gaussian Voxel size: 2.3×2.3x5.0mm Rel. SNR: 1.00 d. FWHM = 2 Routine Contrast Resolution Geometry System Sequence Phantom Scan Recon Common Filter Jobs Offset X 0 : [mm] Output Image Type Both Offset Y 0 : [mm] Recon Method 3D Iterative Iterations 3 Image Matrix 344 Subsets 21 Zoom 1.0 Unrestricted 0 Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2020 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 09/03/2020 | HOOD05162003124365 Healthineers Page 6 of 9 Job Aid | Cross Calibration mMR Biograph – E11P Effective Date: 09/03/2020 | HOOD05162003124365 8. Start Measurement a. Sinogram and Reference Data for further processing are created. b. Wait for completion of NAC and AC reconstruction. i. MR Measurement lasts appr. 20 seconds ii. PET scan may last up to 5 minutes, depending on the activity used. 9. Close Patient on the Exam Card 10. Evaluating the Images a. Load Reconstructed AC images into Viewing Task Card. i. Main Menu select View > 1:1 and Edit > Select Series. b. Navigate to Center of Phantom images using Scroll Bar. i. Draw a Large Circular ROI (appr. 170 cm²) in image. ii. ROI is applied to complete image stack. c. Calculating New Cross Calibration Factor i. Select 12 Central Slice (e.g., images 59-70) d. Enter corresponding Mean Values of ROIs into Cross Calibration Worksheet. i. Enter previously used Cross Calibration Factor (in this case it is 1) into spreadsheet. ii. Enter any additionally necessary data. BOML Unrestricted 0 Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2020 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 09/03/2020 | HOOD05162003124365 Healthineers Page 7 of 9 Job Aid | Cross Calibration mMR Biograph – E11P Effective Date: 09/03/2020 | HOOD05162003124365 Biograph mMR Cross Calibration Worksheet F-18 Phantom Information: Measured Dose: 2,11 mCi 77996000,00 Bq Time: 16:15:13 Residual Dose: 0.00 mC or 0,00 Bg Time: 0:00:00 Net Dose: 2,11 nCi or 77996000,00 Bq Time: 16:15:13 Phantom Volume: 9480 ml Scan Information: Scan Start Time: 17:01:50 Delay To Scan Start: 46,62 min Calculated Specific Activity: Calculated Specific Activity @ Scan Start: 6133,64 Bq/ml Measured Specific Activity: ROI Activity ROI #1 6099,00 Bq/ml ROI #2 6123,00 Bq/ml ROI #3 6135,00 Bq/ml ROI #4 6064,00 Bq/ml ROI #5 6069,00 Bq/ml ROI #6 6099,00 Bq/ml ROI #7 6144,00 Bq/ml ROI #8 6089,00 Bq/ml ROI #9 6088,00 Bq/ml ROI #10 6087,00 Bq/ml ROI #11 6099,00 Bq/ml ROI #12 6117,00 Bq/m Measured Specific Activity @ Scan Start: 6101,08 Bq/ml Dose Cross-Calibration Factor: Currently used Cross-Calibration Factor: 1,00 New Cross-Calibration Factor: 1,01 10248267 VFT 201 01 Unrestricted 0 Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2020 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 09/03/2020 | HOOD05162003124365 Healthineers Page 8 of 9 Job Aid | Cross Calibration mMR Biograph – E11P Effective Date: 09/03/2020 | HOOD05162003124365 Please note that the learning material is for training purposes only! For the proper use of the software or hardware, please always use the Operator Manual or Instructions for Use (hereinafter collectively “Operator Manual”) issued by Siemens Healthineers. This material is to be used as training material only and shall by no means substitute the Operator Manual. Any material used in this training will not be updated on a regular basis and does not necessarily reflect the latest version of the software and hardware available at the time of the training. The Operator's Manual shall be used as your main reference, in particular for relevant safety information like warnings and cautions. Note: Some functions shown in this material are optional and might not be part of your system. Certain products, product related claims or functionalities (hereinafter collectively “Functionality”) may not (yet) be commercially available in your country. Due to regulatory requirements, the future availability of said Functionalities in any specific country is not guaranteed. Please contact your local Siemens Healthineers sales representative for the most current information. The reproduction, transmission or distribution of this training or its contents is not permitted without express written authority. Offenders will be liable for damages. All names and data of patients, parameters and configuration dependent designations are fictional and examples only. All rights, including rights created by patent grant or registration of a utility model or design, are reserved. Copyright © Siemens Healthcare GmbH 2020 Siemens Healthineers Headquarters Siemens Healthcare GmbH Henkestr. 127 91052 Erlangen, Germany Phone: +49 9131 84-0 siemens-healthineers.com Unrestricted 0 Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2020 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 09/03/2020 | HOOD05162003124365 Healthineers Page 9 of 9