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Inline BOLD Neuro 3D (MR) - Eline

This Job Aid will provide workflow instructions on how to evaluate BOLD data Realtime in the Neuro 3D (MR) Task Card on a syngo MR System with DotGO Technology.

Inline BOLD – Neuro 3D (MR) Eline Job Aid Inline BOLD - Neuro 3D (MR) – Eline Job Aid This Job Aid will provide workflow instructions on how to evaluate BOLD data in Realtime in the Neuro 3D (MR) Task Card on a syngo MR System with DotGO Technology. 1. BOLD Sequences Required – select the following Dot Cockpit - Explorer for Inline BOLD to work EXPLORER PROGRAM EDITOR Browse Import Export a. 3D Anatomical sequence (e.g. MPRAGE, SPACE, etc.) SIEMENS SIEMENS >> head >> advanced applications libra b. Field Map 11_mprage_sag_p2 05:12 Morpho c. BOLD moco sequence (e.g., head gre_field_mapping 00:54 Biall DOCEngine ep2d_pace_moco) clinical libraries 01:09 advanced applications libraries gre_field_mapping_2mm bold imaging diffusion and perfusion ep2d_fid_basic_bold_p2 02:58 morphometry pre-surgical planning ep2d_bold_moco_p2 03:23 Optimized protocols for EC programs ep2d_bold_moco_p2_2mm 04:14 library c-spine 03:23 t-spine ep2d_pace_moco_p2 I-spine whole-spine ep2d_pace moco p2 : ep2d_pace_moco_p2 TimCT whole-spine neck soft tissue ep2d_pace_moco_dynt_p2 03:23 2. BOLD Parameter Card thorax heart ep2d_pace moco_filter_p2 03:23 a. Select Dynamic t-maps breast b. Select Motion Correction (Prospective) c. 3D Anatomical sequence (e.g. MPRAGE, SPACE, etc.) i. Position Slices and FoV on localizer ii. Select Apply (Green Checkmark) d. Field Map i. Position Field Map – increase FoV if anatomy not fully covered ii. Select Apply (Green Checkmark) Routine Contrast Resolution Geometry System Physic BOLD Sequence GLM Statistics Motion correction Dynamic t-maps Ignore meas. at start Spatial filter Ignore after transition Model transition states Measurements 60 Temp. highpass filter Delay in TR Threshold 4.00 : Multiple series Off Paradigm size 20 Meas[1] Baseline Meas[2] Baseline Unrestricted 0 Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2020 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 07/31/2020 | HOOD05162003109337 Healthineers Job Aid | Inline BOLD – Neuro 3D (MR) Task Card - Eline Effective Date: 07/31/2020 | HOOD05162003109337 3. Open Patient Browser a. Select 3D Anatomy > select Neuro 3D (MR) icon b. Select Field Map > select Neuro 3D (MR) icon i. Note: sequences must be loaded individually Patient Browser Patient Applications Transfer Edit View Filter Evaluation Sort Options Help J - Tissue Whole_Spine_Level_1 2] t2 flair ax fs R/com/ /11/ 1 Local Database WORKFLOW ADV NEUF ANW HEAD 3 t2_spc_ns_sag_p2_iso_FIL /com/1111 1 Scheduler [4] gre_field_mapping Rioom/ 1/11 1 4. Neuro 3D (MR) Task Card a. Select Fusion Mode Icon b. Select Start Evaluation icon i. Draw a VOI on a 2D Image – area of suspected activation  Multiple VOIs can be drawn Fusion Mode VOI Start Evaluation O auto RPH- And W 817 C 398 Unrestricted 0 Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2020 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 07/31/2020 | HOOD05162003109337 Healthineers Page 2 of 5 Job Aid | Inline BOLD – Neuro 3D (MR) Task Card - Eline Effective Date: 07/31/2020 | HOOD05162003109337 c. Left Mouse Click > Study Folder – closes open Study Folders i. Note: Inline Icons only visible when study folders are closed WORKFLOW AD WORKFLOW_AD Study Study Anatomy ANW HEAD Fieldmap Study Folder Open Study Folder Closed Inline BOLD Controls 5. Neuro 3D (MR) Task Card a. Select Start Inline Mode Icon i. Neuro 3D (MR) Task Card is now receiving signals recorded by Exam Task Card ii. Patient Browser Database – “Start FMRI” series created 6. Exam Task Card a. Select Apply > start BOLD moco Mean measurement (e.g., 67.65 ep2d_pace_moco) NW 57.72. b. Evaluate Data in Realtime 647.79 i. Activation signal intensity (1) M and patient movement evalu- 037.00 $ ated in Realtime M 627.92 10 20 30 40 50 60 Image Acquisition Number 0.11 Translation (2) -0.02 0.16 10 20 30 40 50 60 Image Acquisition Number Tx Ty TE 0.26 Rotation (3)- 0.07 -0.13 10 20 30 40 50 60 O Image Acquisition Number Rx Ry Rz (1) BOLD: Signal intensity over time curves (2) Motion parameter: Translation over time curves (3) Motion parameter: Rotation over time curves Unrestricted 0 Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2020 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 07/31/2020 | HOOD05162003109337 Healthineers Page 3 of 5 Job Aid | Inline BOLD – Neuro 3D (MR) Task Card - Eline Effective Date: 07/31/2020 | HOOD05162003109337 7. Neuro 3D (MR) Task Card > During Measurement a. Select Pause Inline Mode Icon i. Adjust Settings (e.g., ROI size, add additional ROI) =  Note: When Inline Mode is Paused the measurement con- tinues and data continues to be saved to Patient Browser Database b. Stop Inline Mode Icon i. Inline BOLD Exam can be ended once enough activation data has . been collected ii. Offline Evaluation can be performed once inline mode is concluded c. Select Applications > Close Neuro 3D (MR) i. Closes Task Card Patient Applications Volumes Inli WORKFLO Neuro 3D (MR) 0000000 OID. 0000001 Argus 3/4/1981 STUDY 7054 BreVis Fused, MPR BOLD Composing Mean Curve Perfusion (MR) Spectroscopy Close Neuro 3D (MR) Tissue 4D (MR) RP. Vessel View Desktop Unrestricted 0 Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2020 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 07/31/2020 | HOOD05162003109337 Healthineers Page 4 of 5 Job Aid | Inline BOLD – Neuro 3D (MR) Task Card - Eline Effective Date: 07/31/2020 | HOOD05162003109337 Please note that the learning material is for training purposes only! For the proper use of the software or hardware, please always use the Operator Manual or Instructions for Use (hereinafter collectively “Operator Manual”) issued by Siemens Healthineers. This material is to be used as training material only and shall by no means substitute the Operator Manual. Any material used in this training will not be updated on a regular basis and does not necessarily reflect the latest version of the software and hardware available at the time of the training. The Operator's Manual shall be used as your main reference, in particular for relevant safety information like warnings and cautions. Note: Some functions shown in this material are optional and might not be part of your system. Certain products, product related claims or functionalities (hereinafter collectively “Functionality”) may not (yet) be commercially available in your country. Due to regulatory requirements, the future availability of said Functionalities in any specific country is not guaranteed. Please contact your local Siemens Healthineers sales representative for the most current information. The reproduction, transmission or distribution of this training or its contents is not permitted without express written authority. Offenders will be liable for damages. All names and data of patients, parameters and configuration dependent designations are fictional and examples only. All rights, including rights created by patent grant or registration of a utility model or design, are reserved. Copyright © Siemens Healthcare GmbH 2020 Siemens Healthineers Headquarters Siemens Healthcare GmbH Henkestr. 127 91052 Erlangen, Germany Phone: +49 9131 84-0 siemens-healthineers.com Unrestricted 0 Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2020 SIEMENS Master Template Effective Date: 3/5/2020 | HOOD05162003074494 Job Aid Effective Date: 07/31/2020 | HOOD05162003109337 Healthineers Page 5 of 5