PEPFAR Quality Control and Method Validation Activity 12 Handout 3: Calcium Report

Handout 3: Calcium Report 1209 Laboratory Performance Overview Unassayed Chemistry Bilirubin, Total/TBIL 2.0 Calcium 2.0 Jendrassik Grof ISE indirect umol/L mmol/L 1.0 1.0 D 1.0 CVR O 110 210 CVR O HUn Peer Method Peer Method SDI: -0.52 0.20 -1.0 SDI: 0.01 -0.04 1.0 CVR: 0.6 0.5 CVR: 2.5 2.4 # Labs: # Labs: 95 105 2.0 # Points: The other ISE # Points: 5718 6265 parameters (sodium, potassium, chloride) 2.0 also show an 1.0 increase CVI for both levels of controls. 110 210 CVR D 210 CVR O of Peer Method -1.0 Peer Method SDI: -0.12 0.72 SDI: -0.15 -0.20 1.0 CVR: 0.6 0.4 CVR: 3.8 3.7 # Labs: 94 245 -2.0 # Labs: 95 105 # Points: 4716 9699 # Points: 5635 6183 2.0 HOOD05162002658134 Effective Date: 9/8/2017 Laboratory Comparison Report Unassayed Chemistry Analyte Method Units Temp Instrument/Kit Level 1 Level 2 Reagent Mon Cum Mon Cum Calcium ISE indirect (mmol/L mmol/L Your Lab Mean 2.08 2.08 0.105 2.96 2.98 SD CV 0.036 1.7 0.180 0.054 5.0 6.1 1.8 (Peer) CVR 2.5 (Method) CVR 1.0 3.8 1.3 2.4 1.0 (Peer) SDI 3.7 1.3 0.01 -0.03 -0.15 0.12 (Method) SDI -0.04 57 -0.03 -0.20 0.11 # Points 1074 60 1149 Analyte Method Units Temp Instrument/Kit Level 1 Level 2 Reagent Mon Cum Mon Cum Peer Group Mean 2.08 2.08 2.97 2.97 SD 0.043 0.036 0.047 0.042 CV 2.1 1.7 1.6 1.4 # Points 5718 167806 5635 166601 # Labs 95 168 95 Group Values by Method 164 Mean 2.08 2.08 2.97 2.97 SD 0.043 0.036 0.049 0.043 CV 2.1 1.7 1.7 1.4 # Points 6265 190538 6183 189504 # Labs 105 197 105 194 HOOD05162002658134 Effective Date: 9/8/2017 Laboratory Histogram Unassayed Chemistry Calcium ISE indirect 2.16 +2 SD Peer 2.12 Group 2.08 ----------- Mean Range 2.05 - - - -- 2.01 -2 SD Level 1 Jan Feb Mar Apr May Jun Jul Aug Sep Oct NOV Dec Cumulative Mean 0.9 0.025 2.06 SD 1.020 0.018 0.030 0.026 0.025 0.019 0.02 1.0 0.021 1.4 1.3 1.0 0.02% 0.050 105 1.036 CV 5.0 # Points 80 1074 3.06 +2 SD Peer 3.01 ------- ------------- - Group 2.97 ----------. Mean Range 2.93 - - - ---- 2 89 2 SD [Level 2 Feb Mar Apr May Jun Jul Aug pep Oct Nov Dec Cumulative Mean 3.00 3.00 SD 027 2.99 0.9 0.030 0.030 0.039 0.03 0037 0.034 0 049 0.054 CV 1.0 1.0 1.3 1.2 1.1 1.2 1 .1 1.1 1.6 6.1 # Points 72 73 72 11.40 HOOD05162002658134 Effective Date: 9/8/2017 Bias & Imprecision Histogram Unassayed Chemistry Calcium ISE indirect mmol/L Level 1 Bias 5.05 4.27 3.49 2.71 1.93 %) 1.15 0.37 -0.41 -1.19 Jan12 Feb12 Mar12 CV Apr12 Jul12 Aug12 Octiz 0.96 0.86 May 12 Jun12 Sep12 Dec12 1.43 NOVIZ Bias 1.20 1.26 0.91 1.00 0.25 0.25 1.21 0.73 0.23 1.19 1.19 0.25 0.25 1.00 1.34 2.38 5.05 0.25 0.25 0.73 -0.23 Calcium ISE indirect mmol/L cont. Level 2 CV Bias 6.08 5.27 4.46 3.65 (%) 2.84| 2.03 1.22 0.41 -0.40 Jan 12 Feb12 Mar12 Apr12 May12 CV Jun 12 0.90 Jul12 1.00 1.00 1.30 1.28 1.25 1.11 Aug 12 Sep12 Oct12 Nov12 Dec12 Bias 1.07 0.61 1.14 1.64 6.08 0.61 1.95 0.95 0.28 -0.40 -0.06 -0.06 0.28 0.28 0.28 -0.40 HOOD05162002658134 Effective Date: 9/8/2017