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syngo.via MI VB30-VB50 Delta Job Aid

This MI delta job aid is for users who skipped software versions and provides information about features and functionalities that came up between the software versions VB30-VB50 in syngo.via MI.

SIEMENS Healthineers syngo.via MI VB30-VB50 News & Improvements Version 2021 Template Effective Date: 05/27/2019 | HOOD05162003010284 Job Aid Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 syngo.via VB30-VB50 MI News & Improvements SIEMENS Healthineers Table of Contents MI General 3 MI Organ Processing 27 MI Oncology 37 -... .... MI Neurology 53 MI Cardiology 66 PEPconnect 72 syngo.via Innovations 76 2 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 SIEMENS Healthineers MI - News & Improvements MI General 3 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General - syngo.via VB50A SIEMENS Healthineers Siemens Healthineers New User Interface (SHUI) • Stone is the new default schema (Nightsky and Ocean still available in the Configuration Panel Client Settings Advanced Visualization Display And Behavior Export config panel) Access Control Display Types Require authentication on startup Visual Appearance • Icons and button styles updated VRT VRT Reset MiniP Thin MPR/MPR MPR Cinemat Gallery Preset VRT UI schema: Stone Schema Size of fonts and controls: Nightsky Schema Ocean Schema Stone Schema Troubleshoot • GNM and SPECT/CT functionality included on syngo.via - new MI General SIEMENS Healthineers workflow syngo.via • Optimized layouts Flodder • Useful tools for technologist and reading physician • Automate manual tasks Technologist Physician • Robust AI-powered algorithms syngo.via software version VB50 is not commercially available in all countries. 4 Due to regulatory reasons its future availability cannot be guaranteed. Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers New Workflow You will learn: SIEMENS X Healthineers Favorite Tools X Customize the user screen T MI General • Area Text Automatk Custom Rol Cirde Vol Sphere Visual, Automade Hide Hide Lires FAST Contr Windowi Lirgut Tox Alignment Registrat ... Graphics hiding Lock Snapshot Course Synch Nows • Viewing Panel and Layouts MI General Stuch Description: Done Scan Study Time : 10:00:15 Accession Number :1 Energy Window 1: 99m Technatum Radicaharmaceutical DED Study Date : 07.09.2013 Favorite Tools Bone Fused HPR T12 Hybrid Bene 313 Fused Aux Fused 233 L1 • Configure the User Presets L2 L3 . MI Organ Processing L4 Series RAF RAH • Tool Gallery LS MER FUSION SL min 712 S1 SPC 1.0 LI • Favorite Tools Findings Findings APL HPE Findings MER FUSION Finding 1 8L mh AUT SPC 1,0 51 Snapshot 10cm Vv X Finding 2 S2 Snapshot L2 Printing Finding 3 13 L3 S3 Snapshot ARH RAH LS Manin VRTMIF FUSION 1 0cm 13:26 5 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Customize the User Screen Flexible and intuitive user interface SIEMENS x Healthineers favorite Tools X T O. MI General • Tab cards for the most important panels Ares Text Automat Custom Distance ROI Cirde VOI Sphere Visual. Automatic Hide Hide Lires FAST Cardioc Snap Lock Snapshot Centr Windcim Largait Toxi Line Alignmont Registral .. : Graphics Rangos FAST + pineti Auto • Panels can be hidden or made floating MI General o X Stucy Time : 10:00:15 EnergyAndow 1 ; 99m Ternatum Etuch Description: Bune Scar Radiopharmaceutical DFD Study Date : 07.09.2013 Favorite Tools Accession Number : 1 Bone Fused AHL HPA and placed anywhere on the screen to T12 Fused Ar L1 maximize the image space 12 L3 MI Organ Processing L4 Series RAF RAH 15 MER FUSION 12 BPC 1,0 L1 L2 LE/LA Findings IL4 Indings Findings HPL MFR FUSION LG HPR Finding 1 SL mh SPC 1.0 51 Snapshot Finding 2 Printing S2 Snapshot 12 Finding 3 L3 S3 Snapshot ARH RAH Manin VRT MIF FUSIONS 13:26 6 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Viewing Panel and Layouts Predefined layouts MI General Patient Name : NM_xSPECT_01^Osteochondrosis, Arthro:Patient ID : Tc-99m D Study Time : 10:00:19 Accession Number : 1 Assign Layouts ? X Bone MI General LH Bone Designed for different patient data For a study specified by modality and assignment condition, please drag the layouts to the Layout Gallery Preferred Layouts section. The first layout in the list will be your initial layout. types and monitor configurations to Layout operations Favorite Tools MI OrganProcessing Protocol Name visualize and read Oncology, Allgemeine Layouts Save Save layout as layout Bone Fused Cardiology, and Neurology studies. Private Layouts Modality Basic Dynamic WB - Dual WB H Display Time View Intensity Compare Sone Fused Ax NMICT Allgemeine Layouts Planar Savescreen Dynamic + Static + Static + CR Dyn Series • Change a layout Assignment Object Gated Static WB Stati Display Dynamic Static . Static Time View WB - Dual WB- Intensity Compare Planar Savescreen Dynamic + Static + Study Description HE Gated Static WB Functional Functional Fused 2x3 Fused Fused 2×3 Fused 2x4 Movie Axial 3x ... Movie Image Text Configuration • Add Favorite Layouts Fused Fused 2x3 Fused 2x4 Fused 2x2 Hybrid Axial 3x ... + Movie + Movie ... i Checked elements will be shown in customized image text mode Findings Modality NM 4D Fused 4D Hybrid Compare Dynamic + Cardiac AC Cardiac Volume Volu Static + ... NAC Stripe (1) Strip Subcategory * Show All Show All ctio .. 1×3 + ... 2x3 WB + S. None None Pa Patient Name Institution Name • Specify Favorite Siemens Layouts NM DYNAMIC Patient ID Referring Physician's Name NM GATED Hybrid Lung VIQ Hybrid 1x3 Configuration NM RECON TOMO Birth Date, Patient's Sex and Age Manufacturer/Manufacture .. Stic Layouts in more detail Software Versions Compare Compare + Movie Basic Dynamic NM STATIC Time Point Display Time Static - View WB - NM WHOLE BODY Study Date Patient Position Acquisitio ... NM GATED TOMO NM RECON GATED TOMO Series Description Operator Printing NM TOMO Temporal Location Radioisotope Volume Volume Fused Fused 2x3 Fused 2x4 Fused 2x2 Hybrid Stripe (1) Volume Stripe Axial 3x ... Movie + Movie ... Strip ... Show All Configure Image Text accessed NM • Dynamic + Cardiac AC Cardiac Volume Volu Filter Type Slice Thickness from the Configuration Panel Slice Spacing - Show Al Show All Quick Quant ImageType 2D Orientation Cube Acquisition Number * Show All Spacing Between Sli ... Matrix Size Alpha Blending Kernel/Reconstruction Parame .. Image Comments 1 Zoom Factor FOV Image Comments 2 Window Top Compression Rate Slab Thickness Window Bottom 7 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers User Presets Tab Allows you to configure visualization MA Configuration ? × Patient Birthdate, Sex and Age : 01.01.1951, F, 062Y Energy Window 1 : 99m Technetium Study Description Radiopharmaceu parameters such as LUT, alpha Gen MI General blending ratio, slice thickness, and IM_xSPECT_01, Osteochondrosis, Arthrosis Bas Disp Layouts User Presets C-99m DPD slice spacing depending on the data Choose protocol to configure Initial Workflow Step URRENT | CURRENT TUDY 07.08.2013 type of the image displayed. Functi General AC_CT LWS B41s [5] | SPECT LWS [CGZAS 2411 s5mm - AC Enhanced ] None 7.08.2013 | 07.08.2013 LUT Settings 5:19:38 | 14:59:06 IMA n.a. FRM n.a. | 1000 IMA n.a. FRM n.a. P A118,6 | SP A118,6 Favorite Tools Slice Thickness Preferred protocol can be chosen NM CT PT MR Fused o use senes data for thickness settings • Data Type LUT Apply custom thickness settings to configure from a list NM Micro Delta Hot Metal 1 - mm PT Hot Body Hot Body • The Initial Workflow Step displays CT Slice Spacing MR Warm Metal Apply minimum spacing Series the workflow steps or tools that Micro Delta Hot Metal Apply percentage value spacing BW Inv Log 0 % of slice thickness directly can be launched Auxctq Mixing Ratio Ascending Red Apply absolute value spacing. Must not exceed slice thickness. PR FUSION BW Log L min Base (100%) Inverted Grayscale 0 mm SPC 1,0 BW Parabolic Save Reset Heart Findings Import Hot Iron Export Hot Metal Hot Metal New Iso Count Lava 8 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Tool Gallery Tool Gallery Display Types Well-known tools as well as new tools sorted according to their THD VRUNIP VRT VRT Reset MIP MinIP Thin MPRIMPR MPR 2D Cinemat. Gallery Preset VRT category are provided. Automated processes quickly demonstrate Measurements patient’s anatomy and physiology, reduce manual user interaction, and O allow for faster reading of hybrid images, such as: Distance Angle Pixel Lens ROI Circle VOI Sphere Line Annotations • Enhanced Drag & Drop functionality optimized for Hybrid Imaging and Hybrid VRT/MIP T D Marker ATTow Text Edit Comment Automatic Table and Bone Removal, Automatic Registration, and Ranges • Automatic Reorientation for Neurology and Cardiology images Parallel Radial Properties Ranges Ranges Slice .. Add to Favorites nges Artificial Intelligence based tools like Auto Lung 3D, Auto Views, image Visualization • Cinematic VRT, Spine and Rib Label Ranges, and single-click Fast auto Fit to Fit to Hide Hide Color Hide Lines Custom Lock BD Snap Automatic Brain AC- cardiac Segment Acquisiti, Graphics Bars Text Referen. Referen ... . Referen. Layout PC Planes Range Generation with Auto Fast Ranges Windowing • Visualization enhancements with the new tool Automatic Layout, Windowi .. Reset Area Windowi ... Contr ... the new features Remove Image and Frame Summing 3D Editing C Punch Clip Box Clip Plane Spine/Rib Region Anatomy Auto Cardiac Remove Edit Bones Bone Bone Label Growing Visualizer Views Mask Table Opacity Remo 9 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Tool Gallery in Favorite Tools Tool Gallery Display Types THD Add to Favorite Tools: VREMIP VRT VRT Reset MIP MinIP Thin MPRIMPR MPR 2D Cinemat. Gallery Preset VRT Measurements • Frequently used tools can be added from the Tool Gallery to the O Favorite Tools area of the Viewer Distance Angle Pixel Lens ROI Circle VOI Sphere Line Annotations Right-click an icon and choose Add to Favorites from the context T D • Marker Arrow Text Edit menu Comment Ramves Parallel Radial Rao Properties AST Ranges Ranges Slice ... Add to Favestes Iges image Visualization auto Fit to Fit to Hide Hide Color Hide Lines Custom Lock 30 Snap Automatic Brain AC- cardiac Segment Acquisiti ,, Graphics Bars Text Referen ... Referen ... Referen .. Layout PC Planes Windowing Windowi .. Reset Area Windowi ... Contr ... 3D Editing C Punch Clip Box Clip Plane Spine/Rib Region Anatomy Auto Cardiac Remove Edit Bones Bone Bone Label Growing Visualizer Views Mask Table Opacity Remo 10 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Postprocessing Tools You will learn: SIEMENS x Healthineers Favorite Tools X T O. MI General • Enhanced Drag and Drop Area Asset Text Automat Custom Distance Rol Cirde VOI Sphere Visual Automatic Hice Hide Lires FAST Cardiac Srop Lock Snapshot Contr Windowi Linkuit Alignmont Registrat ... Graphics FAST Pinch • Automatic Spatial Registration MI General Bhujcy Time : 10:00:15 Accession Runter:1 Study Description: Bone Sc Study Date : 07.03.2013 EnergyWindow1 : 95m Technatium Radiopharmaceutical DED Favorite Tools Bone Fused H HPA T12 Bone used 223 L1 • Auto Lung 3D tool 12 L3 MI Organ Processing IL4 Series RAF RAH • Auto Views LS MER FUSION 8L mh S1 SPC 1,0 cm • Cinematic VRT L#/LA Findings Findings LG Findings MER FUSION Finding 1 SL mh SPC 1,0 10cm vv 51 Snapshot Finding 2 Printing S2 Snapshot Finding 3 13 S3 Snapshot ARH RAH ManIn VETTAIF FRIENDS 10cm 13:26 11 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Postprocessing Tools - Drag and Drop Enhanced Drag and Drop for Hybrid VRT Imaging • Fuse multiple modalities with RMB and drag and drop Replace All • Manually select the base or the overlay series Fuse as base (MPR/MPR) • Create a fused VRT/MIP with enhanced drag Fuse as overlay (MPRIMPR) and drop functionality Fuse as base (VRT/MIP) Fuse as overlay (VRT/MIP) • Create clinical images for patient review, referring physicians and marketing material • Automatic Table Removal 12 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Postprocessing Tools - Automatic Spatial Registration Automatic Spatial Registration of two SIEMENS Healthineers' ... NM_xSPECT_01, Osteochondro. × + 01.01.1951 F Tc-99m DPD series included Favorite Tools T O MI General auto auto Area Reset FAST Snap Lock Cardiac • Apply and save multiple registrations Contr ... Windowi. Text Automatic Custom Cardiac ROI Circle VOI Sphere Visual Automatic Hide Hide Lines Cardiac Layout Layout Text Mask Alignment Registrat ... Graphics Ranges Planes Referen ... Referen Snapshot FAST for difficult cases Auto Lung Synch 3D Patient Name : NM_xSPECT_01^Osteochondrosis, ArthroBatient ID : Tc-99m DPD Accession Number : 1 Energy Window 1 : 99m Technetium Patient Birthdate, Sex and Age : 01.01.1951, F. 062Y Radiopharmaceutical : DPD Study Description : Bone Scan Favorite Tools • Select the scanner registration to Zoom/Pan allow quality control of hybrid images 3D Reference Point Rotate Windowing IlMovie Serie Automatic Registration Automatic Registration AR Visual Alignment Save as Series Findings Ranges Fit to Segment Geometric Identity Identity *User Defined Mattrix User Defined Mattrix Save Save As Reset Delete 13 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Auto Views SIEMENS .... x Healt oers . 20-Vision 450 DK 1z_1.0mm/s ... 01.01. 1930 M F18-FDG 7.1 ... MI General m/sec_16.8 mirPatient ID : F18-FDC 7.1 mCi (265MBa) Patient Name : 20-Vision 450 DK 1z_1.0mm/sec_16.8 mitEnergy Window 1 :21 Patient Birthdate, Sex and Age : 01.01.1930, M. 089Y Radiopharmaceutical Fluorodeoxyglue Study Description : PET ConUncor ACCT Saphire Study Date : 29.08.2019 Bone Fused HRA HRA MI General Hybrid Bone Auto Views ? > 3x3 Fused Ax. Allows automatic orientation and viewing of CT Modality CT Preset group |Head/Neck AL Favorite Tools and fused data based on the ALPHA Technology. › MI Organ Pro MPR FUSION SL min Name SPC 0,8 Head & Neck Coronal view of head & Head Benefits: Orbitomeatal Line Series Head AC-PC Line r Saphire Study Date : 29.08.2019 HRA Findings • Auto Views Gallery provides clear access to the presets OK Cancel 10cm HAL Printing • The Gallery groups presets according to anatomy and suggests presets • Create clinically relevant images of indicated RAF RAF MPR FUSION MPR FUSION Findings anatomy SL min 10cm SL min SPC 0,8 SPC 0,8 HAL Printing Auto Views Units CT Presets RAH CT Color LUT PET Presets PET Color LUT Reset Windowing 14 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Cinematic VRT Volume rendering technique based on ALPHA SIEMENS x Healthineers Technology. 1144 HH • Provides a photorealistic visualization of the human body • Gives a more realistic impression of the patient's anatomy 1144 A14 45:32 15 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Automated Spine and Rib Labeling H MI_Onco_5TP_1 Universitaetsklinikun _MI_Onco_5TP_1 Universitaetsklinikum • Automatically identify and propose labels for _MI_Onco_5TP_1 *01.01.1982, M, 28Y Biograph 64 _MI_Onco_STP_1 *01.01.1982, M, 28Y R4 R4 Biograph 64 CURRENT CURRENT | CURRENT R5 L4 11.08.2010 CT Enhanced B30f 3.0 [3] | TrueX 2.9 MBq/kg 3 min 211 4s PAC) L5 vertebrae and ribs CT Enhanced B30f 3.0 [3] -- > AQ1:A1 | AQ1:F1 T6 L6 -- > AQ1:A1 # 1 R7 T7 WB5 T8 Depending on the data set, spine and rib labeling or 10:55:59 STUDY 11.08.2010 • R8 T9 3 IMA n.a. FRM n.a. 11.08.2010 | 11.08.2010 SP A81,6 10:55:59 | 10:56:39 3 IMA n.a. FRM n.a. | 102 IMA n.a. FRM n. T10 L8 only spine labeling (only spine on PET segments) 29 SP A81,6 | SP A81,6 R9 T12 Lg R R10 L10 • Rib labels: L, R, and number R11 0cm • Spine labels: C, T, L, S, and number A A MPR FUSION AC 2 x 50,00% If the system proposed labels are not correct, you can 512*512 SL min 28 EQ Filter: ??? mm 280 T 5,00 SUV-bw 35 B 0,00 SUV-bw add or edit the labels. H MI_Onco_5TP_1 Universitaetsklinikum MI_Onco_5TP_1 Universitaetsklinikum MI_Onco_5TP_1 *01.01.1982, M, 28Y 1094 _MI_Onco_STP_1 *01.01.1982, M, 28Y 1094 CURRENT CURRENT TrueX 2.9 MBq/kg 3 min 2i14s (AC) 15 TrueX 2.9 MBq/kg 3 min 2i14s (AC) spine and rib labels T6 -- > AQ1:F1 -- > AQ1:F1 #1 # 1 WB5 WB5 STUDY 11.08.2010 (CT) STUDY 11.08.2010 11.08.2010 11.08.2010 10:56:39 T10 10:56:39 102 IMA n.a. FRM n.a. SP A81,6 T1 T12 R 10cm MPR MIP AC 2007 A AC 2007 A 168*168 168*168 PSF 211 EQ FIN All-pass PSF 2i14s, All-pass EQ Fir r: ??? mm 5,00 SUV-bw EQ Filter: ??? mm 0,00 SUV-bw 5,00 SUV-bw B 0,00 SUV-bw spine labels only (PET) AC_CT AC_CT 16 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Automatic Spine and Rib Label Ranges Result Ranges with spine and rib label overlays SIEMENS .. : NM_xSPECT_01, Osteochondro .. × Healthineers + 01.01.1951 F Tc-99m DPD Patient Name : NM_xSPECT_01^Osteochondrosis, ArthrPatient ID : Tc-99m DPD Study Time : 10:00:19 Patient Birthdate, Sex andAge : 01.01.1951, F, 062Y Study Description : Bone Scan Study Date : 07.08.2013 Accession Number : 1 Energy Window 1 : 99m Technetium Radiopharmaceutical : DPD Zoom/Pan H H MI General • Create Parallel or Radial Ranges with spine and rib 3D Reference Point T.12 label overlays Rotate 2. Windowing 1.3. Bill Movie Favorite Tools Create result ranges with spine and rib label Automatic Registration • Lock Reference Lines 14 ARH overlays on VRT/MIP Ranges Parallel Ranges Fit to Segment Radial Sliced Ranges Punch Radial Ranges Series • Reviewing cases with quick anatomical references Clip Plane Curved Ranges Remove Table Spine Ranges Bone Removal Tools EP. HPR H Findings T12 L1 L1 2. 5 L2 . 5. L2 L3 L3 Printing L4 L4 ARH L5 L5 S1 S1 S 17 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Automatic Layout Tool The Automatic Layout tool automatically displays SIEMENS Healthineers MI_OrganProcessing_Bone, C ... HA 01.01.2001 M Tc-99m DPD planar Nuclear Medicine images based on the Favorite Tools X T O MI General available data. Ares Reset Text Automa Tea Cardiec ROI Circle VOI Sphere Visual Automatic Hide Hide Lines FAST Contr .. Windowl ... Mask Alignment Registrat .... . Graphics Ranges Planes Referen Referen . Snapshot + Auto Lun Synch The layout is created based on the type of data, MI General X Patient Name : _MI_OrganProcessing_Bone"CoPatient ID : Tc-99m DPD Radiopharmaceutical : HDP Patient Birthdate, Sex and Age : 01.01.2001, M, OStudy Description : Bone Scan Study Date : 23.04.2002 Study Time : 09:53:58 Favorite Tool • nergy Window 1 : 99m Technetium Bone Tomo MI_OrganProcessing_Bone, Complete Tc-99m DPD size, number, aspect ratio and orientation of the Functional Static- *01.01.2001, M, 1Y Axial 3x: View 23.04.2002 10:08:16 monitors Series Automatic Layout X • The images to be displayed are assigned to Select Dynamic Static WB Gated display groups based on data types Current V Findings ? fps • The data is displayed in a layout created Printing automatically by the system 200 • The Select Groups Panel provides functions for controlling the image types displayed in the 100 100 $ 100 ₴ image area 11 11:16 18 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Sum Frames Frame Summing SIEMENS .. Healthineers NM_xSPECT_01, Osteochondro ... x 01.01.1951 F Tc-99m DPD Patient Name : NM_xSPECT_01^Osteochondrosis, ArthroPatient ID : 10-99m Sty Description : Bone Scan Study Date : 07.08.2013 Accession Number : 1 Energy Window 1 : 99m Technetium Patient Birthdate, Sex and Age : 01.01.1951, F, 062Y Radiopharmaceutical : DPD Study Time : 10:00:19 MI General • Activated with right click context menu 1 Remove Image • Automatically sums 2D dynamic images Favorite Tools | Sum Frames • Manual summing is still available Configure Frame Summing X Series Manual Frame Summing Auto Frame Summing Frames to Sum Auto Summing Set a numeric value for the number Automatic values are chosen for the of sequential 2D dynamic frames to number of sequential 2D dynamic sum together in stripe view. frames to sum together in stripe view. Findings OK Cancel Printing 19 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Remove Image Remove Image SIEMENS x Healthineers .. MI General X MI General General • Quickly removes unwanted images from the viewing segments ritto Segment HH Favorite Tools • Activated with right click on context menu De IL Line MI Organ Processing is March Remove Image • This prevents from reviewing unnecessary images sedas Findings 100 > 5:41 20 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Organ Processing Application Launching Organ Processing application redeployment SIEMENS .... X Healthineers ... T16_Hemangioma E ? * 1/1/1948 M Tc_99m_Labeled ... MI General X Cardiac Series Cholecystic MI General Static - WB - Dual Planar Gastric Add Study Basic Dynamic The MI Organ Processing step is Display Time Intensity Gated • Parathyroid Series Name Volume Functional Fused 4D Hybrid Pulmonary Stripe Axial 3x ... Axial 3x ... 2×3 + ... automatically displayed in the control area AutoLayout 2D Renal Current Thyroid CT NM, 4/24/2008 Favorite TIS MI Organ Processing Liver Scan Display SPECT . CT 1 ........................ UCO ucol *SPECT CT 5.0 B31s [3] 3 Phase Cardiac Cardiac Cardiac Display General IQ SPECT Lung PET CT Planar Savescre. Slice Static Wholeb ... xSPECT Favorite templates can be added by right Bone Di ... Compar ... CT Slice ... Slice Dis ... Slice Dis ... Compare Display Display Gated D ... Review Compar ... SPECO Display Display Display AC CT 5.0 BO8s [2] • Processing Activities 10 ... Hemangioma SPECT [AC Recd 19 ... Hemangioma SPECT [AC Reco clicking a template and selecting favorite Blank >>Ad-Hoc Processing 10 .. Hemangioma SPECT [AC Reco Series 10 ... Hemangioma SPECT [No AC R All template Liver Flow 20 mCi Tc99m 10 ... 99m Technetium Liver Immediate 20 mCi Tc99m 10 ... RT ANTERIOR LT 10 ... LT POSTERIOR RT Findings 10 ... RAO • The MI Organ Processing step can be Favorite Tools X 10 ... LPO 10 ... RT LATERAL configured to launch automatically in the auto 10 ... Area Reset Auto Lung Automatic Fit to LT LATERAL Contr .... Windowi ... 3D Layout Acquisiti ... 10 ... RPO User Presets configuration of MI General O .. Configuration ? X TO ... LAO Custom ROI Circle VOI Visual Automatic Printing Text Freehand Alignment Registrat ... Liver Delay 20 mCi Tc99m 10 ... RT ANT LT 20 MIN Hide Hide Lines Parallel Radial Cardiac Graphics Ranges Ranges Mask 10 ... LT POST RT 20 MIN 10 ... RAO 20 MIN auto Cardiac Snap Snapshot FAST Layouts User Presets Lock 10 ... LPO 20 MIN Planes Referen ... Referen ... Ranges 10 ... RT LAT 20 MIN Choose protocol to configure Initial Workflow Step auto $10 ... LT LAT 20 MIN Fit to Cardiac Segment FAST ... Panel to appgate Mlindows. General None 10 ... LAO 20 MIN + 21 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Auto Lung 3D (1/5) Allows you to automatically quantify ventilation and perfusion of SPECT/CT lung scans. • Artificial Intelligence (AI) based algorithm automatically segments CT of right and left lung into 5 individual lobes Al-powered SPECT quantification and CT volume results are healthcare • provided for all lung lobes based on the automatic segmentation of the CT volume • Automatic Report CT NM ThorRoutine 1.5 B70s Lung Tomo [- corrected Recon, Flash3D 8 4 4 - AC ] 1/20/2016 10:37:23 AM 1/20/2016 10:13:09 AM Slice Thickness : 1.5 mm Attenuation corrected : Yes Volume (ml) Volume (%) Counts (konts) Counts (%) R Upper 812 21 4,673 20 R Middle 350 1.316 6 R Lower 832 22 6.396 27 Total R Lung 1,994 52 12,385 53 L Upper 842 22 4.855 21 L Lower 993 26 1,835 5.976 26 Total L Lung 48 10,831 47 Performance testing is based on CT images with a slice thickness of 2mm or less. 22 Data courtesy of University Hospital Basel, Basel, Switzerland. Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Auto Lung 3D (2/5) Accessed from Favorite Tools T MI General • Tool Gallery 1% Auto Lung O Area Custom auto 3D Reset Text Cardiac ROI Circle VOI Sphere Visual Automatic Hide Hide Lines FAST Cardiac Snap Lock Layout Cardiac Contr ... Windowi ... Layout Mask Alignment Registrat ... Graphics Ranges Planes Referen ... Referen. Snapshot FAST • Auto Lung 3D complex tool % Auto Lung Synch 3D • The Auto Lung 3D workflow step is MI General Patient Name : USBLunge005 Study Date : 19.10.2015 Patient ID : Anonymous Study Time : 08:46:26 Patient Birthdate, Sex and Age : 01.01.1958, M, 056Y Study Description : Lung Perfu Energy Window 1 : 99m Technetium Radiopharmaceutical : MAA Favorite Tools available below the Viewing panel of the General A USBLunge005 application and the Data Selection step is Basic Dynamic Static - WB - Dual Anonymous Display Time Intensity *01.01.1958, M, 56Y Co CURRENT enabled by default 1 Planar Volume Functional 4D Hybrid Lung Tomo [- corrected Recon, Flash3D 8 4 4 - AC ] Gated Stripe Axial 3x .... 2×3 19.10.2015 09:22:22 SP H1651,3 Series • Complex tool provides additional workflow Volume Fused 2x3 Hybrid 3x3 Fused Stripe (1) + Movie Axial 3x .... R R MPR steps: › MI Organ Processing 10cm • Data Selection Auto Lung 3D X • Registration Data Selection Findings 128*128 • Segmentation Confirm Data • Results Data courtesy of University Hospital Basel, Basel, Switzerland. 23 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Auto Lung 3D (3/5) Clinical value Thoracic surgeons and pulmonologists rely on nuclear medicine studies for pre- and post-surgical evaluation of lung perfusion and ventilation to make informed treatment decisions. Limitations in clinical use Conventional planar lung perfusion and ventilation studies to determine regions and volumes are often inaccurate due to the limitations of 2D imaging. 24 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Auto Lung 3D (4/5) Manual delineation of the lung lobes is time consuming and may be L Upp RUpp prone to error. • 3D SPECT/CT improves delineation and quantification of L Mid lung segments compared to planar SPECT imaging SPECT/CT studies provide 3-dimensional displays of lung perfusion L LOW R LOW • and ventilation, allowing more accurate visualization and analysis of anatomy and function compared to a 2D planar image • Incorporation of CT enables more precise anatomical segmentation which enhances the accuracy of lobar lung volumes estimation Data courtesy of University Hospital Basel, Basel, Switzerland. 25 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI General SIEMENS Healthineers Auto Lung 3D (5/5) 2D versus 3D SPECT/CT Publications and clinical validation 3D-Quantitated lung perfusion 99mTc-MAA SPECT/CT: Impact on intended management in comparison to planar (2D) lung perfusion Is hybrid SPECT/CT necessary for pre- CrossMark scan in lung cancer patients interventional 3D quantification of relative Alin Chirindel2, Michal Cachovan3, Alexander Hans Vija4, Makhmudbek Mallaev7, Daiana Stolz6, Michael Tamm1, Didier Lardinois7, Damian Wild5 andGuillaume Nicolas2 lobar lung function? +] Author Affiliations Abstract Daniela Knollmann1, Jerome Avondo2 and Wolfgang M. Schaefer1" 299 Objectives: Prior to lung resection, predicting the postoperative lung function is of paramount importance. The current practice uses planar (2D) scintigraphie have * Correspondence: wolfgang. previously shown that 3D quantitated SPECT is more accurate than 2D in determining lobar perfusion. We aim to assess the impact of 3D-quantitated lung perfusion SPECT/CT [email protected] Abstract on the operability of lung cancer patients. Kliniken Maria Hilf, Nuclear Medicine, Viersener Str. 450, 41063 Background: In pulmonary malignancies pre-interventional 3D estimation of relative Methods: Post-hoc, single centre study in consecutive patients with suspected or known lung cancer, undergoing pre-operative evaluation with lung perfusion imaging and Moenchengladbach, Germany lobar perfusion is established to predict post-interventional functional outcome pulmonary function tests (PFT). Tc-MAA planar and SPECT/CT lung perfusion scans were performed on a single imaging system (Intevo, Siemens). The lobar contribution to Full list of author information is particularly in patients with borderline lung function. Aim was to test whether the total lung perfusion was assessed using the established 2D-projection method and the 3D-anatomical method (CT Pulmo 3D and xSPECT-Quant - Siemens). The accuracy available at the end of the article of the two evaluation methods was tested against a computational anthropomorphic chest phantom (XCAT). Predictive post-operative PFT (PPO PFT) was calculated according quantification from SPECT-scanners (non-hybrid) is as accurate as from SPECT/CT- 3D is more accurate than 2D, and may help optimize 3D estimation of relative lobar perfusion predicts post- surgical management of lung cancer. interventional functional outcome (particularly in patients with borderline lung function). 1. J Nucl Med May 1, 2019 vol. 60 no. supplement 1 299. 26 2. European J Hybrid Imaging 2, 18 (2018). Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 SIEMENS Healthineers MI - News & Improvements MI Organ Processing 27 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI Organ Processing SIEMENS Healthineers • Renal Analysis Improvement SIEMENS Healthineers • Image Registration Activity R TP5 MM × * 01.01.1982 M F-18 FDG > Cardiac MI Reading Cholecystic MI Reading Gastric MI Organ Processing Parathyroid i Select a category, then an icon from the Pulmonary Template Browser to start organ processing. To place a workflow template in this area, right Renal click on an icon and select Favorite Template. > Thyroid Display Processing Activities Blank Ad-Hoc Processing ............... Dynamic Heart Lung NM_CT NM_MR NM NM NM_NM NM_NM Phase Co ... Ratio Manual Fus ... Manual Fus ... Manual Fus ... Static Fusio ... Wholebody ... 28 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI Organ Processing SIEMENS Healthineers Renal Analysis (1/5) • Extrapolate T1/2 in the renal evaluation to Settings |Display ROIS Results Kidney Aorta better align with SNMMI Procedure Data Selector % % 100 100 Left Kidney Kidney Right Kidney Standards Left Backgr. Right Back Fit_Left Kid ... 500 Max-I TMax-R Quality Control 450 400 • Use case: T1/2 is not reached in the allotted 350 rfit-L 300 acquisition time, but the reading physician 0 0 Fr:1 153K Pixel Units 64x64 250 [/2-R Renal Fr:1 3134Pixel Units 64x64 Processing Table of Patient Parameters 200 still requires a T1/2 value for reporting Parameters Values 150 Counts/Second Renal Protocol Generic (None) 100 Kidney Depth Method Standard 50 Flexible Display Patient Name NM Renal_01_SymbiaS Renal Retention Patient ID Tc-99m MAG3 • Sex Male 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 Age 62 Minutes Reference BSA 1,73 m2 Hard Copy Split Uptake Interval ( .. 2,0 - 3,0 Radiopharmaceutical 2,7 mCi 99m Technetium MAG3 Method Adult Left Kidney Flow Hematocrit 0,00 FRONT 450 400 Table of Result Summary 350 Parameters Left Right Total Curve Fit 300 On Off Split Function (%) 48,3 51,7 250 Renal Retention 0,156 200 Renal Retention 0,159 Time of Max (min) 0,401 4,002 150 Time of 1/2 Max (min) 40,01 11,5 100 Counts/Second Complete Extrapolated 50 O 5 10 15 20 25 30 35 40 45 50 55 O Seconds Setup 29 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Organ Processing SIEMENS Healthineers Renal Analysis (2/5) To see this new feature, open a dynamic renal SIEMENS .. Healthineers ' NM_Renal_01_SymbiaS x study with MI Reading. * 01.01.1952 M Tc-99m MAG3 Cardiac MI Reading + Choose Renal Flow and Diff Proc from the Cholecystic MI Reading Gastric category Renal. MI Organ Processing Parathyroid 1 Select a category, then an icon from the Pulmonary Template Browser to start organ processing. To place a workflow template in this area, right Renal click on an icon and select Favorite Template. eg Renal ACE Renal Bubeck Renal Flow Inhibitor Proc MAG3 TER P .. and Diff Proc Renal Gates Renal Generic Renal Itoh Proc Renal Renal Oriuchi Renal GFR Proc MAG3 Proc Oberhausen ... Proc Transplant Thyroid Display Processing Activities Blank Ad-Hoc Processing › All 30 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Organ Processing SIEMENS Healthineers Renal Analysis (3/5) Compared to the right kidney, in this example, Settings |Display ROIs Results Kidney Aorta the clearance of the left kidney (red curve) is Data Selector % % 100 100 Left Kidney Kidney Right Kidney so slow, that T1/2 can not be reached within Left Backgr ... Right Back ... 500 Max-L TMax-R the 20 minute acquisition. Quality Control 450 400 - 350 300 Therefore, field in the results table remains Fr:1 153K Pixel Units 64x64 Fr: 1 3134Pixel Units 64x64 250 TV-R O Renal Processing 200 empty. Table of Patient Parameters Parameters Values 150 Counts/Second Renal Protocol Generic (None) 100 Flexible Display Kidney Depth Method Standard 50 Patient Name NM Renal_01_SymbiaS Patient ID Tc-99m MAG3 Male 3 5 6 8 9 10 11 12 13 14 15 16 17 18 19 Sex O Age 62 Minutes Reference BSA 1,73 m2 Hard Copy Split Uptake Interval (. 2,0 - 3,0 Radiopharmaceutical 2,7 mCi 99m Technetium MAG3 Method Adult Flow Hematocrit 0,00 450 400 Table of Result Summary 350 Parameters Left Right Total 300 Curve Fit Off Off Split Function (%) 48,3 51,7 250 Renal Retention 200 0.156 0,159 Time of Max (min) 0,401 4,002 150 Time of 1/2 Max (min) 11.5 100 Counts/Second Complete 50 MA 5 10 15 20 25 30 35 40 45 50 55 O Setup Seconds 31 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Organ Processing SIEMENS Healthineers Renal Analysis (4/5) On the Settings page, the option to create a Settings Display ROIs Results fit of a kidney curve can be selected. Data Selector Renal Method ROI . Captopril Comparison Gates GFR (DTPA) Method Use Existing ROIs Itoh ERPF (MAG3) M Apply Background Subtraction Quality Control Manual Generic (None) . Automatic MAG3 (Without Samples) X-Shift: 2 Pixels Threshold : 31 % Y-Shift: 2 Pixels Oberhausen Renal Oriuchi Clearance (MAG3) Offset: 2 Pixels Processing Bubeck (TER) Height: 100 % Width: 100 1% Flexible Display Patient Information Options Parameters Kidney Depth (cm) Injected Dose Bladder Hard Copy Calculate Blood Flow Parameters Options Calculate Blood Flow Parameters Manual T - Start M T-Max M T-1/2 Max Use Cortical ROIs T-2/3 Max Use Cortical ROIs T-Max-> T-1/2 T-Max-> T-2/3 Renal Retention Apply Deconvolution Slope T-1/2 Apply Deconvolution Cmax Manual T - Upslope Definition Upslope Time Complete Split Function Range Upslope Split Function: 2 - 3 minutes M Left Curve Fit Right Curve Fit Setup 32 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Organ Processing SIEMENS Healthineers Renal Analysis (5/5) This fit can be used to extrapolate the T1/2 time Settings Display ROIs Results Kidney Aorta point beyond the end of the scan. Data Selector % % Kidney 100 100 - Left Kidney Right Kidney Left Backgr. - Right Back. Max-I Fit_Left Kid. 500 TMax-R The value is now shown in the results table. Quality Control 450 400 350 Tfit-L 300 0 0 Renal Fr:1 153K Pixel Units 64x64 Fr:1 3134Pixel Units 64x64 250 Processing Table of Patient Parameters 200 Parameters Values 150 Counts/Second Renal Protocol Generic (None) 100 Kidney Depth Method Standard 50 Flexible Display Patient Name NM Renal_01_SymbiaS Patient ID Tc-99m MAG3 O Sex Male 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 Age 62 Minutes Reference BSA 1,73 m2 Hard Copy Split Uptake Interval ( ... 2,0 - 3,0 Radiopharmaceutical 2,7 mCi 99m Technetium MAG3 Method Left Kidney Flow Adult Right Kidney Hematocrit 0,00 Aorta 450 400 Table of Result Summary 350 Parameters Left Right Total 300 Curve Fit On Off Split Function (%) 48,3 51,7 250 Kidnau Caunte (com) 24.665 22201 AQGE 200 Renal Retention 0,156 0,159 MI Time of Max (min) 0.401 4,002 150 Time of 1/2 Max (min) 40,0' 11,5 100 Counts/Second Complete * Extrapolated 50 O 5 10 15 20 25 30 35 40 45 50 55 O Setup Seconds 33 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Organ Processing SIEMENS Healthineers Image Registration/Image Fusion • Prepare data for synchronized viewing such as side by AI side displays or even more advanced techniques such Settings Registration Object vs Target Object vs Target Matrix Optional vs Object Matrix as alpha blending Data Selector Optional vs Object Default Default Optional vs Target Transverse Sagittal Coronal AC_CT LWS B70s, 07.08.2013 SPECT LWS [Flash3D 256x256 8i4s6mm - AC ], 28.08.2013 A HU 78 % • Re-slice data in preparation for viewing on other Image Registration workstations such as PACS Flexible Display • Supports manual registration for volume data, including gated and dynamic data Hard Copy 52 • For planar data, manual registration is supported • For manual registration, visual verification and T: 1,5 T: 1,0 manual interaction are required to ensure that both S: 1,5 S: 1,0 P: 188,3 P: 305,2 126|B70s 314 870s P: 306.6 B70s 315 O datasets are properly registered Transverse Sagittal Coronal Complete ............ ............ ............ ............. .......... Rotation Z 0,00 Rotation × 0,00 Rotation Y 0,00 Setup Translation (mm): × 0,00 Y 0,00 Z 0,00 Landmarks 34 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI Organ Processing SIEMENS Healthineers Image Registration Activity SIEMENS .. • Open a SPECT/CT study with MI Reading Healthineers Server: 192.168.236.155 S500_ ? MI_NM_SPECT_CT_1 * 01.01.1930 M MI_NM_SPECT_CT_1 Cardiac • Choose one of the Fusion Proc templates MI Reading Q + Cholecystic MI Reading Gastric from the category Ad-Hoc Processing MI Organ Processing Parathyroid 1 Select a category, then an icon from the Pulmonary Template Browser to start organ processing. To place a workflow template in this area, right Renal click on an icon and select Favorite Template. Thyroid Display Processing Activities x Blank Ad-Hoc Processing + Dynamic Heart Lung NM_CT Manual NM_MR Manual NM_NM Manual NM_NM Static NM_NM Series Series Series Filter Fusion Proc Fusion Proc Generic Proc Series FWHM Series Phase Extractor Proc Reformat Ge ... Curve Generi ... Extractor Proc Series Series ROI Series Static Static Merge Phase Compr .. Fusion Proc Fusion Proc Wholebody F ... Arithmetic G ... Dynamic Co. Proc All Findings Navigator DO - Name Value Source 35 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Organ Processing SIEMENS Healthineers Image Registration Activity Different tools can be used to apply manual shift or A re-angulation to the object series: Settings Registration . Object vs Target Object vs Target Matrix ptional vs Object Matrix Data Selector Optional vs Object Default Default Optional vs Target Transverse Sagittal Carosal • Mouse AC CT LWS 870s, 07.08.2013 SPECT LWS [Flash3D 256x256 8i4s6mm - AC ], 28.08.2013 HU 78 % Image • Sliders Registration • Numerical values Flexible Display The resulting registration matrix can be saved. Hard Copy 52 T: 1.5 S. P: 188,3 P: 305.2 B70s 126 B70s 314 370s O Transverse Sagittal Coronal Complete .......... Rotation Z 0,00 Rotation X 0,00 Rotation Y 0,00 Setup Translation (mm): 0,00 Y 0,00 Z 0,00 Landmarks 36 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 SIEMENS Healthineers MI - News & Improvements MM Oncology 37 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MM Oncology SIEMENS Healthineers SIEMENS Display Improvements Healthineers Server: 146.254.133.144 Siemens Healthineer TP5_MM 1/1/1982 M F-18 FDG MM Oncology Q + TP5 MM TPS_MM • Hybrid VRT Radial Ranges MM Oncology Reading CURRENT | CURRENT CURRENT | CURRENT 3D Reading STUDY 8/11/2010 STUDY 8/11/2010 Spine and Rib Labeling CT Enhanced B30f 3.0 [3] | TrueX 2.9 MBg/kg 3 min 2114s (AC) CT Enhanced B30f 3.0 [3] | TrueX 2.9 MBq/kg 3 min 211 4s (AC) • 8/11/2010 | 8/11/2010 8/11/2010 | 8/11/2010 RECIST 1.1 10:55:59 AM | 10:56:39 AM 10:55:59 AM | 10:56:39 AM 3 IMA ~206 | 102 IMA ~138 3 IMAn.a. | 102 IMAn.a. SP F426.5 | SP F426.5 SP A78.6 | SP A78.6 Solid Liver Lymph Generic Lesion RECIST Measurement Improvements e RAF Lung CA AEF 9nco Auto Trending • Interactive Trending for PET and CT MM Reading F • Automated Tumor Burden Trending 0: 50.00% SL min a 50.00% MPR FUSION 280 T 5.00 SUV-bw Manip VRT MIP FUSION 35 B 0.00 SUV-bw 0.00 SUV-bw A CURRENT CURRENT STUDY 8/11/2010 STUDY 8/11/2010 TrueX 2.9 MBq/kg 3 min 2114s (AC) TrueX 2.9 MBq/kg 3 min 211 4s (AC) -- > AQ1:F1 -- > AQ1:F1 Findings Navigator 8/11/2010 8/11/2010 10:56:39 AM 10:56:39 AM 102 IMA~138 Name Value 102 IMA n.a. Source RA 1005 Tools 10cm L Synch Align Text Hide Hide Lines Reset Graphics Timepoints F AL Edit Layout Undo Redo SLOO Snapshot Print Image Export T 5.00 SUV-bw T 5.00 SUV-bw Image MPR B 0.00 SUV-bw MIP B 0.00 SUV-bw 12:37 PM AC_CT AC_CT 38 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MM Oncology VB40 SIEMENS Healthineers Hybrid VRT - Radial Ranges Hybrid VRT/MIP provides a visual summery of the current disease state, illustrating the distribution of functional uptake with the anatomical reference in a single image. Zoom/Pan • Radial sliced ranges used to create series of Remove Table images cut radially around a pivot 3D Reference Point Windowing • Lock Reference Lines Enabled in fused segments Rotate Clip Plane 3TP 4 Biograph 6 Ranges Tools Parallel Ranges *1/1/1930, M, 77Y CURRENT | CURRENT CT [2] | HD Fit to Segment Radial Ranges -- > AQ1:A1 | AQ1:F1 PET3 * Open Radial Ranges STUDY 9/20/2007 Radial Sliced Ranges 9/20/2007 | 9/20/2007 12:26:04 PM | 12:27:20 PM ..................... Curved Ranges R Set to FOV Segment Total Angle: 360.0 . Angle Between Images: 8.6 º Result View 0cm Set to Reference Segment Global View VRT/MIP MiniP Thin MIP VRT Gallery MPR/MPR Send To Context Menu MPR 39 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MM Oncology SIEMENS Healthineers Hybrid VRT - Radial Ranges Define: Universitaetsklinikum MI_Onco_5TP_1 Universitaetsklinikum MI. MI_Onco_5TP_1 Universitaetsklinikum _MI_Onco_5TP_1 MI_Onco_5TP_1 Number of images +01.01.1982, M, 28Y Biograph 64 _MI_Onco_5TP_1 *01.01.1982, M, 28Y Biograph 64 *01.01.1982, M, 28Y Biograph 64 • CURRENT | CURRENT CURRENT | CURRENT CURRENT | CURRENT CT Enhanced B30f 3.0 [3] | TrueX 2.9 MBq/kg 3 min 2i14s (AC) CT Enhanced B30f 3.0 [3] | TrueX 2.9 MBq/kg 3 min 2i14s (AC) CT Enhanced B30f 3.0 [3] | TrueX 2.9 MBq/kg 3 min 2i14s (AC) -- > AQ1:A1 | AQ1:F1 -- > AQ1:A1 | AQ1:F1/ -- > AQ1:A1 | AQ1:F1 # 1 # 1 #1 ; WB5 WBS WB5 STUDY 11.08.2010 STUDY 11.08.2010 STUDY 11.08.2010 11.08.2010 | 11.08.2010 11.08.2010 | 11.08.2010 11.08.2010 | 11.08.2010 10:55:59 | 10:56:39 10:55:59 | 10:56:39 10:55:59 | 10:56:39 • Image resolution PR RA • Reference image • Click Start to create the images Manip VRT MIP FUSION AC 2 R Manip VRT MIP FUSION AC 2 Total-Angle: 350.0 -.- Manip VRT MIP FUSION Between Images: 10.0 . F 512*512 œ: 50,00% 512*512 EQ Filter: ??? mm EQ Filter: ??? mm o: 50,00% 512*512 T 5,00 SUV-bw T 5,00 SUV-bw EQ Filter: ??? mm 5,00 suy B 0,00 SUV-bw B 0,00 SUV-bw 0,00 suv-bw Parallel Radial ~ Curved • Click Accept to save the range _MI_Onco_5TP_1 H Universitaetsklinikum _MI_Onco_5TP_1 Parallel Radial Curved *01.01.1982, M, 28Y Biograph 64 CURRENT | CURRENT Preview Preset Select the Preset STUDY 11.08.2010 Preset Select the Preset CT Enhanced B30f 3.0 [3] | TrueX 2.9 MBq/kg 3 min 2114s (AC) 3 IMA n.a. | 102 IMA. n.a. Angle between Images 10,0 Angle between Images 10,0 + Number of Images 36 Number of Images 36 Field of View 1122,5 = x 1122,5 mm Field of View 1122,5 x 1122,5 mm AL Presets Orientation Image Series Presets Orientation Image Series Image Resolution Normal Range Series Name VRT Range Image Size 1169 x 1169 pixels Image Comment Fusion Data Set Data set 1+2 Include Reference Image x 50,00% AC 2 5,00 SUV-bw Start Accep Close Start Accep Close Manip VRT MIP FUSION 0,00 SUV-bw 40 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MM Oncology SIEMENS Healthineers Automated Spine and Rib Labeling H MI_Onco_5TP_1 Universitaetsklinikum _MI_Onco_5TP_1 Universitaetsklinikum Automatically identify and propose labels for _MI_Onco_5TP_1 *01.01.1982, M, 28Y Biograph 64 _MI_Onco_STP_1 *01.01.1982, M, 28Y R4 R4 • Biograph 64 CURRENT | CURRENT R5 L4 CURRENT 11.08.2010 CT Enhanced B30f 3.0 [3] | TrueX 2.9 MBq/kg 3 min 21143 @AC) L5 vertebrae and ribs CT Enhanced B30f 3.0 [3] -- > AQ1:A1 | AQ1:F1 T6 -- > AQ1:A1 # 1 R7 T7 L6 T8 L7 # 1 WB5 • Depending on the data set, spine and rib 10:55:59 STUDY 11.08.2010 11.08.2010 | 11.08.2010 R8 T9 3 IMA n.a. FRM n.a. SP A81,6 10:55:59 | 10:56:39 T10 L8 3 IMA n.a. FRM n.a. | 102 IMA n.a. FRM n.a. SP A81,6 | SP A81,6 R9 T11 labeling or only spine labeling (only spine on Lg R R10 R R10 T12 L10 PET segments) R11 10cm R1 L11 L12 • Rib labels: L, R, and number A A MPR FUSION AC 2 • Spine labels: C, T, L, S, and number 512*512 @ 50,00% SL min EQ Filter: ??? mm 280 T 5,00 SUV-bw 35 B 0,00 SUV-bw nz H CH If the system proposed labels are not correct, MI_Onco_5TP_1 Universitaetsklinikum MI_Onco_5TP_1 Universitaetsklinikum _MI_Onco_5TP_1 you can add or edit the labels. *01.01.1982, M, 28Y 1094 MI_Onco_5TP_1 *01.01.1982, M, 28Y 1094 CURRENT CURRENT spine and rib labels TrueX 2.9 MBq/kg 3 min 2i14s (AC) TrueX 2.9 MBq/kg 3 min 2i14s (AC) -- > AQ1:F1 T6 -- > AQ1:F1 # 1 # 1 WBS WBS (CT) STUDY 11.08.2010 STUDY 11.08.2010 11.08.2010 11.08.2010 10:56:39 102 IMA n.a. FRM n.a. SP A81,6 T11 T12 R R 10CM spine labels only (PET) MPR MIP AC 2007 A AC 2007 A 168*168 168*168 PSF 2i14s, All-pass PSF 2014s, All-pass EQ Filter: ??? mm 5,00 SUV-bw EQ Filter: ??? mm 0,00 SUV-bw 5,00 SUV-bw -0 0,00 SUV-bw AC_CT AC_CT 41 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MM Oncology SIEMENS Healthineers Spine and Rib Labeling - How to Start 1. CT or fused segment: Distance Line I ROI Circle MI_Onco 5TP_1 UnivePixel Lens MI_Onco_5TP_1 Top right corner menu > Spine/Rib Label *01.01.1982, M, 28Y Marker CURRENT Arrow 11.08.2010 CT Enhanced B30f 3.0 [3] Angle 2. Auto-labeling of spine starts -- > AQ1:A1 VOI Sphere # 1 Text T 10:55:59 3 IMA n.a. FRM n.a. Propagate Markers SP A81,6 RECIST/WHO + VOI 3. Labeling of ribs has to be started separately on mini-tool Isocontour Solid Lung Lesion Segmentation bar Start Lung CAD Auto-labeling running Spine/Rib Label Show Spine/Rib Label R + 10cm 4. Labels are ready for review (if CT image quality requirements are fullfilled) 5. Confirm labels after review A MPR 280 42 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MM Oncology SIEMENS Healthineers Spine and Rib Labeling - Mini-Tool Bar + Start rib labeling algorithm ............. ............................. Confirm labels Add multiple Reset to initially Add single rib label after verifying spine labels computed labels correct locations 43 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MM Oncology SIEMENS Healthineers Spine and Rib Labeling - Manipulating Spine Labels Adding a single vertebra label • Right-click > Insert and Propagate T9 In spine label menu, choose vertebra label spine label menu • T11 Adding multiple vertebra labels Mini toolbar > Insert multiple spine labels icon T • L • Position the mouse pointer over a vertebra and click • Select vertebra label from spine label menu S + • Position the mouse pointer over another vertebra and click to continue adding • To stop adding, deselect Insert multiple spine labels icon ...... Editing vertebra labels Label and Propagate • Select a vertebra label, right-click for context menu Label Single spine label context menu • Choose action to change or delete the label: Delete and Propagate Single: No effect on adjacent labels Delete Single • • and Propagate: Adapt labels above and below in anatomical order … ... ... ... 44 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MM Oncology SIEMENS Healthineers Spine and Rib Labeling - Manipulating Rib Labels .. Adding a rib label Label and Propagate rib label context • Mini toolbar > Add Rib Label icon Label Single menu • Position mouse pointer over a rib and click Rib label is created Delete and Propagate • Delete Single Editing rib labels • Select a rib label and right-click for context menu • Choose appropriate action to change or delete the label: • Single will not affect adjacent labels • and Propagate will adapt labels above and below in anatomical order … 45 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MM Oncology VB40 SIEMENS Healthineers Interactive Trending Somer SMOKEY • Automatic display of clinically relevant reading01 Domo guide MTV_TLG. Multiple TimeP. * 1/1/1982 M F-18 FDG calculations with respect to the A ... Against Baseline. 7/31 /2008 237 days elopsed baseline examination and linked LIVO12 PT LIV012 Max: 42.07 SUV-b (+42%) Max: 42.07 SUV-bw (+42%) findings Peak 27.0 SUV by / Size 1 cm3 (+4196) Peak: 27.0 SUV-bw / Size: 1 cm3(+4)\ Thresh: 11,78 SU w/ 28.9 Threstt 11:78 SUV-tw/ 28% A Days elapsed between baseline and Against Baseline: 7/31/2008 • R LIVON CT RECIST 11 Dam: 275 mm 237 days elapsed Max: Orth, Diam.: 26:7 mm current timepoint Volume 7.362 ml -bw (+42%) -bw / Size: 1 cm3 (+41%) UV-bw / 28 % • Percentage change for CT and PET segmentations New case here LIVO14.CT RECIST 1.1 Diam. 23:8 mm Max Orth, Diam 19:8 Volume: 4.141 ml R LIVOR R LIVO13 PT LIVO13 Max: 29 53 SUV bw Peak 19.08 SUV-bw./ Size: 1 cm3 Max: 29 53 SUV-bw Peak 19.08 SUV-bw / Size: 1 cm3 Thresh: 6.74 SUV-bW / 23 % Thresh 8 74 SUV-bw / 23 16 to activate Windows 46 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MM Oncology SIEMENS Healthineers Interactive Trending MM Oncology Configuration Configuration X Show change rate for linked Calculation Visualization Initial Layouts Measurements Lung CAD Trending Multi-foci Segmentation Archiving measurements Tools MM Oncology Deactivate tools after creating a measurement MM Oncology Reading Display evaluation text only when selected 3D Reading Automatically create propagated markers for new measurements RECIST 1.1 Show change rate for linked measurements Solid Liver Lymph Generic RECIST Lesion Node + VOI Quick Quant Sphere Radius 5 4 mm Lung CAD AEF Onco Auto Board Zoom Trending VOI Sphere MM Reading OK Cancel 47 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MM Oncology SIEMENS Healthineers Automated Trending Wholebody MTV and TLG / Total Activity (Tumor Burden) can Findings details ? × now be trended across timepoints. This helps to assess the disease status and the effectiveness of treatment. Series Details Trending 1. Configure measurement tool to display MTV, TLG, or Patient Name _MI_Onco_5TP_1 Graph of Selected Lesion Modality PET CSV Baseline Prior 02, 28.07.2009 . Tumor Burden Metric Volume Add Print Copy Export to Snapshot Total Activity Hottest Lesions Volume (MTV) TLG 2. Measure lesions in at least two timepoints TLG Trend for Tumor Burden 3. Open Finding details, select Graph of Tumor Burden % Change Baseline SUV-bw x cm3 and choose Metric to be displayed in Trending Graph 350 578,72 300 514,42 VOI Isocontour Properties X Display the following evaluations on PET/SPECT data: 250 450,12 Max (Maximum) Max.eq (Maximum Equivalent) 200 385,81 Peak (Highest Average 1cm3 Sphere) Peak.eq (Highest Average 1cm3 Sphere Equivalent) Mean (Average) 150 321,51 Mean.eq (Average Equivalent) SD (Standard Deviation) 100 257,2 SD.eq (Standard Deviation Equivalent) TLG (Total Lesion Glycolysis) / Total Activity (Mean x MTV) 50 192,91 Volume (MTV) (Molecular Tumor Volume) Thresh (Threshold of VOI Max) 128,60 Deauville Score 11 Please review results as the system only evaluates Deauville scores from 2 to 5. 50 64,30 Prior 02 28.07.2009 Prior 01 19.04.2010 CURRENT 11.08.2010 Date DD.MM. YYYY OK Cancel 48 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MM Oncology SIEMENS Healthineers Lesion Scout and AutoID (1/3) Powerful identification and measurement capabilities: The Lesion Scout tool can be used to automatically detect and segment regions of high radiopharmaceutical uptake on RefLIV Max: 3 PET or 3D tomographic studies for the purposes of whole- Mean: SD: 0 PERCI body tumor burden calculation. With the optional Auto ID regions on 18F-FDG, studies can be Distance Line automatically classified as included or excluded (e.g. ROI Circle Pixel Lens physiological uptake). This is achieved with an Artificial Marker FIT Intelligence (AI) algorithm. Arrow Angle VOI Sphere Text T R Proposed classifications are color coded, can be toggled and Propagate Markers RECIST/WHO + VOI Isocontour presented in the preview mode for review, and confirmed by Solid Lung Lesion Segmentation the user prior to final acceptance. Lesion Scout Start Virtual Planar Reconstruction = The user can hide color rendering on MIP during preview. Al- powered healthcare Data courtesy of Seeland University Hospital, Naestved, Denmark. syngo.via VB50 and its features are not commercially available in the United States. Future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further details. 49 The accuracy of lesion classification has not been verified by the FDA. The lesion classification presented by Auto ID is only a proposal. Effective Date: 05/05/2021 | HOOD05162003191471 All findings must be evaluated and accepted by the physician before MTV/TLG is calculated. Unrestricted © Siemens Healthineers, 2021 MM Oncology SIEMENS Healthineers Lesion Scout and AutoID (2/3) Auto ID: Initial Layouts Measurements Lung CAD Trending Lesion Scout Archiving • Is activated only if checkbox is enabled in configuration settings tab card 4,5 SUV Save As save Delete • Presets can be saved SUV Max greater than Manual Threshold Make sure metric is SUV with value of Auto ID • SUV Automatically analyze and suggest physiological areas for exclusion from burden calculation. • Auto ID is trained for FDG only! Selection Threshold with value of 4,5 ¢ SUV Supported for [18F]-FDG radiopharmaceutical • PET/CT only! No PET/MR! No SPECT/CT! only. Please ensure all foci are reviewed before accepting. E Adult only 0,5 ¢ • 0,5 % ml • Limitations to 50 foci ex factory might be reached quickly, consider to change config.net after evaluating the system capacity and capabilities • Lesion Scout and Auto ID can be resource-hungry in longer axial scans, higher matrix with more segmentation results, in those cases a prediction algorithm foresees the max-out RAM scenario and will block the user from running the application with a message 50 The accuracy of lesion classification has not been verified by the FDA. The lesion classification presented by Auto ID is only a proposal. Effective Date: 05/05/2021 | HOOD05162003191471 All findings must be evaluated and accepted by the physician before MTV/TLG is calculated. Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 SIEMENS Healthineers MI - News & Improvements MI Neurology 51 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI Neurology SIEMENS Healthineers SIEMENS Database Comparison Healthineers Server. 192.168.236.155 $500_t ? H & MI Neuro FDG 1 MI_Onco_5TP_1 X MI Neuro Da ... X * 01.01.1929 F MI Neuro FDG 1 MM Oncology MI Neurology View Annotations Tools Databases Help MI Neurology Q + K abc • Multi Frame Secondary Capture MI Reading Database Comparison Uptake SSP Uptake Neurology Analysis PET Brain (AC) F^18^[^ 18^Fluorine] Fused Statistics Analyses Fusion to CT _MI_Neuro_FDG_1 Scale: 0.5 FoV: 21.1x24.1cm MI_Neuro_FDG_1 Scale: 0.5 FoV: 21.2x24.1cm -MI_Neuro_FDG_1 cale: 0.5 FoV: 21.8x24.1cm • F 079Y 01-Jan-1929 PET: W 25165.3 L 15378.8 |F 079Y 01-Jan-1929 is PET: W 25165.3 L 15378.8 F 079Y 01-Jan-1929 PET: W 25165.3 L 15378.8 Fusion to Template Universitaetsklinikum Erlangen Universitaetsklinikum Erlangen Universitaetsklinikum Erlangen Primary _MI_Neuro_FDG_1 _MI_Neuro_FDG_1 _MI_Neuro_FDG_1 • Filter Statistics 1:2 Analysis Database Cortical Striatal Sobiract Anatomical Review ------------ 3D Hybrid View Color Maps PET Striatal Analysis -10 -8 -6 - Statistics (#Std Dey) Stereotactic Surface Projection Filter Statistics • Multi Frame Secondary Capture 3D Volume Effect Regions of Interest Key Images Factory Databases AAL regions • Name Mean (Upta ... # Std.Dev fr Amygdala ( ... 5.28 1.8 Axial Coronal Sagittal Amygdala ( .. 5.11 2.0 PET:14-Oct-2008 09:50:52 Slice 56/91 |PET:14-Oct-2008 09:50:52 Slice 55/109 PET:14-Oct-2008 09:50:52 Slice 48/91 Angular gyr ... 5.18 -3.6 Angular gyr ... 5.13 -3.7 Statistics SSP Statistics CT SD-CT Anterior cin ... 5.05 -1.4 FDG2A: FDG-PET Biograph Age Range: 46 - 79 Normalization: Cerebellum + Vermis (AAL) Anterior cin. 5.36 -1.1 Cortical Analysis Findings Navigator Calcarine fi .. 5.96 -2.0 Right Lateral S Left Lateral S Anterior Posterior Calcarine fi .. 6.61 -1.4 Name Value Source Caudate nu ... 4.92 -2.0 MFSC Neur Caudate nu. 4.47 -1.7 Cerebellum ... 4.03 0.2 Cerebellum ... 3.61 -0.1 Cerebellum ... 4.52 -0.4 P AA PR Cerebellum. 4.23 -0.6 Multi Frame Secondary Capture Cerebellum ... 5.85 2.0 • Cerebellum. 5.90 2.1 Cerebellum ... 6.32 -0.3 Cerebellum. 6.18 0.4 Cerebellum ... 5.31 -2.0 Cerebellum. 4.74 -1.3 Corahallum Superior Inferior Right Medial Left Medial Tools Values displayed are body weight SUVs Subtraction L Synch Full Tex Hide Hide Lines Reset Graphics Timepoints • Multi Frame Secondary Capture Edit Snapshot Print Image Export Undo Redo Layout Image 15:25 52 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Neurology SIEMENS Healthineers Multi Frame Secondary Capture MFSC –Multiframe Secondary Capture View Annotations Help • abc + Uptake SSP Uptake • One-click export entire volume for Database Comparison Amyloid F^18^[ 18"Fluorine] AV-45 Fusion to MR . Alzheimer's disease (amyloid) Scale: 0.5 FoV: 27.5x24.1cm - Alzheimer's disease (amyloid) Scale: 0.5 FoV: 27.5x24.1cm - Alzheimer's cisease (amloid) O-L-L PET: W 22170 L.13516.7 0-/ --- PET: W 22170 L 13516.7 O-C- archiving Fusion to Template 201011222 201011222 201011222 Analysis Anatomical Review Neurology Analysis Color Maps PET Primary ...... -10 -8 -6 4 2 0 2 1:2 Statistics (#Std Dev) 6 Stereotactic Surface Projection Databar Cortical Striatal Subtract 3D Volume Effect Filter Statistics Regions of Interest Key Images AAL regions Name Mean (Upta ... # Std. Dev fr Amygdala 11084.9 6.2 Aiall Amygdala ( 10595.3 49 PET:-/- Slice 42/91 T- Angular gyr ... 14284.5 6.8 Angular gyr. 14598.2 7.0 Statistics SSP Statistics MR SD-MR Anterior cin .. 14997.1 5.7 florbelapir2A: florbetapir PET Age Range: 50 - 93 Normalization: Cerebellum (orbetapir) Anterior cin 15630.2 6.3 Calcarine fi. 12358.2 7.4 - Alzheimer's disease (amyloid) A Scale: 0.5 Fov: 27.5x24.1cm Alzheimer's die O-L-L Calcanine fi. 12171.6 4.9 Caudale nu 6626.7 -0.4 201011222 01011222 Caudate nu 6816.1 -0.1 Cerebellum 7841.8 0.2 Cerebellum. 7842.9 0.1 Cerebellum 8901.2 0.5 Cerebellum 9935.6 1.8 Cerebellum. 8261.6 1.5 Cerebellum 8544.4 21 Cerebellum. 7382.1 0.3 Cerebellum 7368.8 0.2 Cerebellum 5588.3 -1.4 Cerebellum. 5301.2 -1.9 R Carhallum Values displayed are (-) ARY PET:-4. Axial Sice 42/91 T:-4. HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 53 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI Neurology SIEMENS Healthineers Multi Frame Secondary Capture - How to Create it 1. Select a fused or non-fused image segment View Annotations Tools Databases Help Delete Delete 2. Choose either: + Select All -‘ ++ Snapshot View Ctrl+S Snapshot Screen Ctrl+Shift+S • Tools > Create MFSC MFSC icon Create MFSC Ctrl+M • Preview 3. MFSC series will show up in Series Navigator under Export Ctrl+E Additional Data and in Findings Navigator Copy to Clipboard Ctrl+C Configure ROI Categories 54 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Neurology SIEMENS Healthineers Fused Statistics MR SD-MR • Anatomical images of the patient Statistics SSP Statistics can be shown with an overlay of florbetapir2A: florbetapir PET Age Range: 50 - 93 Normalization: Cerebellum (florbetapir) MI_Neuro_Amyloid_AD_1 A Scale: 0.38 _MI_Neuro_Amyloid_AD_1 S Scale: 0.38 MI_Neuro_Amyloid_AD_1 SScale: 0.38 Fov: 21.8x31.1cm the statistics image (overlayed M-A- FoV: 21.1x31.1cm |M -/- - /- FoV: 21.2x31.1cm |M -/- - /- CT/MR) _MI_Neuro_Amyloid_AD_1 MI_Neuro_Amyloid_AD_1 MI_Neuro_Amyloid_AD_1 Neurology Analysis Primary C R LR A Database Cortical Strlatal Subtract PET:-/- Axial |PET:-/- MR: 25-Aug-2008 10:45:39 Slice 42/91 |MR:25-Aug-2008 10:45:39 Coronal |PET:-/- Sagittal Slice 52/109 |MR:25-Aug-2008 10:45:39 Slice 46/91 55 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Neurology SIEMENS Healthineers Fused Statistics - How to Show them Statistics SSP Statistics CT SD-CT FDG2A: FDG-PET Biograph Age Range: 46 - 79 Normalization: Cerebellum + Vermis (AAL) _MI_Neuro_FDG_1 Scale: 0.38 - _MI_Neuro_FDG_1 Scale: 0.38 MI_Neuro_FDG_1 S Scale: 0.38 FoV: 21.8x31.1cm F 079Y 01-Jan-1929 FoV: 21.1x31.1cm F 079Y 01-Jan-1929 FoV: 21.2x31.1cm F 079Y 01-Jan-1929 Universitaetsklinikum Erlangen! Universitaetsklinikum Erlangen ! Universitaetsklinikum Erlangen • Depending on the available _MI_Neuro_FDG_1 _MI_Neuro_FDG_1 _MI_Neuro_FDG_1 anatomical data (CT or MR), Database Comparison choose the appropriate tab and adjust transparency Fusion to CT LR Fusion to Template • Control transparency and/or Analysis filtering of overlaid statistics Anatomical Review image Color Maps PET:14-Oct-2008 0 CT:24-Nov-2008 13:01:53 Axial PET:14-Oct-2008 09:50:52 Coronal PET:14-Oct-2008 09:50:52 Sagittal P Slice 56/91 CT:24-Nov-2008 13:01:53 Slice 55/109 CT:24-Nov-2008 13:01:53 Slice 48/91 PET CT Statistics SSP Statistics MR SD-MR florbetapir2A: florbetapir PET Age Range: 50 - 93 Normalization: Cerebellum (florbetapir) _MI_Neuro_Amyloid_AD_1 A Scale: 0.38 MI_Neuro_Amyloid_AD_1 $ Scale: 0.38 MI_Neuro_Amyloid_AD_1 ; SScale: 0.38 Fov: 21.8x31.1cm M --- -- FoV: 21.1x31.1cm |M -/- - /- FOV: 21.2x31.1cm |M -/- - /- -10 -8 -6 -4 -2 0 2 4 6 _MI_Neuro_Amyloid_AD_1 MI_Neuro_Amyloid_AD_1 MI_Neuro_Amyloid_AD_1 Statistics (#Std Dev) 18 Stereotactic Surface Projection v 3D Volume Effect Filter Statistics Transparency SD CT PET:-/- Axial |PET:-/- Sagittal MR: 25-Aug-2008 10:45:39 Slice 42/91 | MR: 25-Aug-2008 10:45:39 Coronal |PET:-/- Slice 52/109 |MR:25-Aug-2008 10:45:39 Slice 46/91 56 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Neurology SIEMENS Healthineers Filter Statistics Statistics SSP Statistics CT SD-CT FDG2A: FDG-PET Biograph Age Range: 46 - 79 Normalization: Cerebellum + Vermis (AAL) - M_Neuro_FDG_1 Scale: 0.38 - M_Neuro_FDO_1 S Scale: 0.38 -MI_Neuro_FDO_1 $ Scale: 0.38 FOV: 21.8x31.1cm F 079Y 01-Jan-1929 FOV: 21.1x31.1em F 079Y 01-Jan-1929 FoV: 21.2x31.1cm F 079Y 01-Jan-1929 Universitactsklinikum Erlangen! Universitactsklinikum Erlangen: Universtaetsklinikum Erk _M_Neuro_FDG_1 M_Neuro_FDG_1 _MI_Neuro_FDG_1 ............ Statistics values from the Statistics color bar can be filtered so that only the standard deviation values of concern are visible on the statistics images. R ... Standard statistics volume The filtered-out values appear as gray background PET:14-Oct-2006 09:50.52 Slice 50/91 PET.14-Oct-2006 09-50.52 Slice 55/109 PET-14-Oct-2008 09:50:52 Sactta ............... • Statistics SSP Statistics CT SD-CT FDG2A: FDG-PET Biograph Age Range: 46 - 79 Normalization: Cerebellum + Vermis (AAL) Right Lateral S Left Lateral S Anterior S osterior SSP statistics image • The filtered-out values appear as gray background Superior Inferior Right Medial Left Medial Statistics fused with MR or CT • The filtered-out values become translucent Statistics SSP Statistics CT FDG2A: FDG-PET Biograph Age Range 46 - 79 Normalization: Cerebellum + Vermis (AAL) -_M_Neuro FDG_1 Scale: 0.38 - MI Neuro_FDG 1 S Scale: 0.38 . MI_Neuro_FDG_1 SScale: 0.38 FoV: 21.8x31.1cm F 079Y 01-Jan-1929 FoV: 21.1x31.1cm F 079Y 01-Jen-1929 FoV: 21.2x31.1cm F 079Y 01-Jan-1929 Univers toetskinkum Erlangent Universitactsklinikum Erlangen Universitoetskinkum Erlangen M_Neuro_FDG_1 MI_Neuro_FDG_1 M_Neuro_FDG_1 ......... -- LR PET:14-Oct-2008 09:50:52 CT 24.Nov.2008 13:01:32 Since som FET:14-Oct-2003 08.50.52 propos PET:14-Oct-2003 08:50:52 ............ Slice 56/109 CT.24-Nov-2008 13:01:32 ................................... 57 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Neurology SIEMENS Healthineers Filter Statistics - How to Do it Database Comparison • Adjust handles to remove negative or positive standard deviation numbers Fusion to CT • Set checkmark to apply slider settings to SSP display Fusion to Template Analysis Anatomical Review Color Maps PET CT -10 -8 -6 -4 -2 2 4 Statistics (#Std Dev) Stereotactic Surface Projection v 3D Volume Effect y Filter Statistics Transparency SD CT 58 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Neurology SIEMENS Healthineers Factory Databases in Striatal Analysis Elle View Annotations Tools Databases Help Neurology Analysis abc Primary C Striatal Analysis BRAIN SPECT "123%lodine I-123-Datscan . DATSCAN30 Seain: 0.53 FoV: 21.2x19cmn . DaTSCAN30 Scale: 8.53 FoV: 21.2x19cm . DaTSCAN30 Scale: 0.53 FoV: 21.8x13cm Fusion to Template M-072Y -L KM: W 272 L 135 |MO72Y -- NM: W 272 L 136|MO72Y -/- NM: W 272 L 13 1:2 DaTSCAN 301 DATSCAN 30 1 DaTSCAN 30 1 Analysis Database Cortical Striata Subtract Color Maps NM Reference Brain Selection X Factory Normal Database provided for Normalization Region • Occipital lobe (AAL) Show Striatal Regions of Interest Patient name: -_MI_Neuro_DaTSCAN_medium_4 Key Images ROI Patient age: 65 Striatal Analysis to compare with Stratum (L) Striatum (R) Patient sex: M Patient radiopharmaceutical: Unknown database of normal subjects Please select a radiopharmaceutical: 1231-FP-CIT NM.15-Sep-2011 13:57:34 - - DATscan and F-DOPA* Siab Graph • DATSCAN30 Available Reference Brains for Selected Radiopharmaceutical: M 072Y -J. Name Age Range Sex Normalization Region DaTSCAN 30 1 FPCIT1A SPECT_Flash3D_(CTAC) [Read-Only] 16 - 88 Occipital lobe FPCIT2A SPECT_FBP_(Chang-AC) [Read-Only] 16 - 88 M/F M/F Occipital lobe • Choose an appropriate database 08 Reset Striatal ROI Position according to radiopharmaceutical and Link Left and Right ROI for Editing Display Striatal Box scan parameters OK Exit NM:15-ST0-2011 13:57:34 * This feature is not commercially available in the U.S. 59 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Neurology SIEMENS Healthineers Striatal Analysis Databases - How to Use • Analysis workflow step shows an additional graph tab. This graph displays the patient's left and right ratio values for a selected Region, along with the values of all subjects present in the database. The graph illustrates patient left (blue) and right (red) ratios against reference (gray). • In the results summary table segment, the patient’s uptake ratios are displayed for anterior and posterior putamen and also normal reference values and Z-scores. Patients are considered normal if their ratios are within +/- 2 SD of the reference mean value. Slab Graph + Database: FPCIT1A_SPECT_Flash3D_(CTAC) (16 - 88 Y) Patient: M, 65 Y 5.6- Database Patients Normalization region: Occipital lobe Plotted values: Striatum 5.4- Patient Left Patient Values Reference Values 5.2- Ratio to Normalization Region Z - Score 5 - Patient Right Left Right Mean + 2 SE Left Right 4.8- Mean + 2 SE Striatum 4.58 4.57 4.00 + 0.79 + 1.48 1.46 4.6- Caudate 4.80 4.49 4.09 + 0.82 + 1.74 + 0.98 4.4- - Reference Mean Putamen 4.28 4.67 3.87 + 0.79 + 1.04 + 2.03 4.2- Anterior Putamen 4.61 5.02 4.02 + 0.84 + 1.40 Mean - 2 SE 2.36 Posterior Putamen 3.79 1.19 3.65 + 0.78 + 0.35 + 1.37 4 - Asymmetry Measures 3.8- Striatum DVR Striatum Asymmetry 0.17 % 3.17 + 5.22 % - 1.15 3.6- Caudate Asymmetry 6.70 % 3.75 + 5.64 % 1.05 3.4- Putamen Asymmetry 8.74 % 3.83 + 5.40 % + 1.82 3.2- Putamen (L) / Caudate (L) 0.89 0.95 + 0.10 - 1.10 3- Putamen (R) / Caudate (R) 1.04 0.95 + 0.10 1.75 2.8- Ratio and asymmetry calculated using mean of the brightest 75% of voxels in striatal regions. 10 20 30 40 50 60 70 80 90 Age Copy Export Results 60 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Neurology SIEMENS Healthineers Striatal Analysis Databases SPECT-Ioflupane (DaTscan®) PET-FDOPA* Two normal SPECT-Ioflupane (DaTscan®) databases are offered: One normal PET-FDOPA database is offered in Striatal Analysis: • FDOPA1A: FDOPA-PET is built from OSEM3D reconstruction • FPCIT1A_SPECT_Flash3D_(CTAC) is built from Flash 3D reconstructions of Siemens Symbia T2 scanner data with CT of Siemens Biograph mCT scanner data with CT attenuation attenuation correction. correction. • FPCIT2A_SPECT_FBP_(Chang-AC) is built from FBP reconstructions of the same Siemens Symbia T2 scanner This database is derived from PET-FDOPA scans of 53 normal data with Chang attenuation correction. patients with an age range of 42 to 90 years old (20 male and 33 female). The database consists of patients with given clinical These databases are derived from SPECT-Ioflupane (DaTscan®) conditions who were referred by their Neurologists to the imaging site and were found to have a negative FDOPA scan and scans of 241 normal patients with an age range of 16 to 88 no evidence of Parkinsonian neurodegeneration (at baseline years old (117 female and 124 male). These "normal" subjects and at ≥18-month follow-up). are not healthy volunteers but patients who were referred to the imaging sites with a clinical condition but had a negative DaTscan® exam and didn’t have any confirmed • White Paper WIP neurodegenerative Parkinsonism at baseline or at follow up (≥ 3 years). * This feature is not commercially available in the U.S. 61 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Neurology SIEMENS Factory Databases in Striatal Analysis Healthineers SIEMENS Healthineers supermar • Create New Database Scenium_DaTScan_positive1 X M 2012022000 View Annotations Tools Databases Help Add Current Subject to Database Create New Database • Normalization region should be set here Striatal Analysis Manage Databases .23^lodine 1-123-Datscan - Scenkm_DaTScan_positive1 Scale: 0.65 Fov: 21.1x20.2cm - Sconium_DalScan_positivet Scale: 0.66 FoV: 21.1x20.2cm . Scerium_DaTScan_positivet Scales Scale: B.ES FoV: 21.8x20.2cm Fusion to Template M O64Y -1- HM; W.127.2 L 95.4 M 054Y -L IM: W 127.2 L 95.4 M 064Y - MPA: W/ 127.2 L. 95.4 and cannot be subsequently modified 2012022000 201 2022000 201 2022000 Analysis -- Color Maps NM ...................... ....................... • Manage databases .................. ................. Normalization Region Occipital lobe Show Striatal Regions of Interest Key ages ................................................. It is necessary to restart Striatal Analysis ............. • Create New Database X after import Database Name DaTSCAN database This is a test database Coronal • After restart, the normal database can be 12.48.06 Sice 40/109 NE 23.Aug-2011 12:46:06 Sagittal Slice 59:91 ...................... Description Normalization region: Occipital lobe Patient Values selected Ratio to Normalization Region Database Settings Manage Databases X Modality NM Radiopharmaceutical 1231-FP-CIT Normalization region Occipital lobe Proportion of Brightest Voxels 100.0% Database name Modality Radiopharmaceutical Sex Age Range DaTSCAN database NM 1231_FP_CIT New Template Basal Ganglia SPECT [Read-Only] NM Other M/F/O 0 - 999 Template Basal Ganglia PET [Read-Only] PET Other M/F/O 0 - 999 Edit Reference Brain Selection Create Cancel Parent name: - Sconium_DafScan_possivel Pament mes 1:123 Datscan NE:23-Aug-2011 12:46:06 62 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI Neurology SIEMENS Healthineers Following enhancements are available in MI SIEMENS Healthineers MI_Neur Scenium_HMPAO2 ... x Tc-99m HMPAO Neurology: Favorite Tools MI Neurology O. stance ROI Circle Area Text Snapshot FAST Rangres Hide • Brain AC-PC automatically orients PET or MI Neurology X Patient Name :_MI_Neuro_Scenium_HMPAO2"SPECT_MR_Epilepsy Patient ID : Tc-99m HMPAO Patient Birthdate, Sex and Age : 01.01.1987, F, 017Y Study Description : Brain Scan Study Date : 16.01.2004 Study Time : 12:35:19 Energy Window 1: 99m Technetium Radiopharmaceutical : ECD Accession Number : 0 Favorite Tools SPECT Neurological data to provide quick ALF HLA Fused Basic Volume Functional Fused 2x4 HL Axial 3x ... Display Strip ... Axial 3x ... + Movie _MI_Neuro_Scenium_HMPAO2, SPECT_MR_Epilepsy 0,00 MB MI_Neuro_Scenium_HMPAO2, SPECT_MR_Epilepsy Tc-99m HMPAO Tc-99m HMPAO 0,00 MBq MI_Neuro_Scenium_HMPAO2, SPECT_MR_Epilepsy Tc-99m HMPAO 0,00 MBq reading in a clinically relevant orientation *01.01.1987. F. 17Y *01.01.1987. F. 17Y *01.01.1987, F. 17Y Hybrid 3x3 CURRENT CURRENT CURRENT STUDY ID 1 STUDY ID 1 STUDY ID 1 SPECT [RECON] . 2. SPECT [RECON] 1. 3 SPECT [RECON] .4. 18.01.2004 16.01.2004 16.01.2004 MI Neurology Analysis 12:55:02 12:55:02 12:55:02 SP H69,8 SP L212,0 SP P135,0 Series • Optimized Neurology Layouts in the Layout RAH ALF RAH Primary Monitor MAR MFR Gallery 1:2 Database Cortical Striatal Subtract indings 128"128 128*128 128*128 Relaunch • Neurology Application Relaunch option ALH HPL HPL . 5, 6 Printing RAH ALH RAH MPR FUSION MPR FUSION MPR FUSION SL min SL min SL min SPC 0,5 SPC 0,5 SPC 0,5 10 cm 63 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 SIEMENS Healthineers MI - News & Improvements MI Cardiology 64 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI Cardiology SIEMENS Healthineers You will learn: SIEMENS althineers MI Cardiology MI Cardiology • Optimized Cardiology Layouts 67 yo Male Supine, IR. SC.CIAC SICTAG Filter: None Mid-HLA Perfusion Cardiac Planes O O • O LAD Favorite Tools U LOX MI Cardiology Reading -- O O O O • Cardiac Mask Tool Region Mean LAD 30.3 +/- 9.1 (37.5) % LCX 78.5 +f- 8.5 (101. RCA Series • Cardiac FAST Ranges TOT 79.6 +f- 8.6 (104.1) % Favorite Tools Cardiac Configuration Send only short axis O T. DE RSICTAC • FIter, Non Mid-HLA Perfusion VNOM series to the cardiac analysis applications U LOX • Cardiac Application Relaunch option O Region Mean - LAD LCX 83.2 46- 6.9 (101.0) RCA 1 4-7.8 (36.0) • New version syngo.MBF VB20 TOT 47-9.7 (103.3) Mid-Y 65 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Cardiology SIEMENS Healthineers Application Versions VB50A S Updated Cardiac application versions for VB50A AA • Cedars 2017 CEDARS-SINAI • 4DM 2018 ® • Available Delta OLT MI Cardiology Applications Part 2 on PEPconnect INVIA Medical Imaging Solutions SIEMENS Healthineers 66 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 MI Cardiology SIEMENS Healthineers New Tools Cardiac Planes automatic orientation of SIEMENS. DEMO_Cedars_Symbia_Cardiac .. x • Halthineers ... 01.01.1969 M Tc99m PET and SPECT Cardiology data in short Favorite Tools MI Cardiology axis, horizonal long axis and vertical long O Cardiac Cardiac auto ! Area Visual FAST. Contr. Snapshot Synch Mask Planes Alignment axis views provides quick reading in clinically relevant orientation MI Cardiology Patient Name : DEMO_Cedars_Symbia_Cardiac^EU Patient ID : Tc99m Patient Birthdate, Sex and Age : 01.01.1969, M, 039Y Study Description : Cardiac Perfusion Study Time : 11:37:02 Accession Number : 1 Energy Window 1 : 99m Technetium Radiopharmaceutical : Sestamibi xx ********************************************************** ALF HAL HAL Favorite Tools Basic Fused 2x3 DEMO_Cedars_Symbia_Cardiac, EU Planar Savescreen Volume DEMO_Cedars_Symbia_Cardiac, EU DEMO_Cedars_Symbia_Cardiac, EU Volume *01.01.1969, M, 39Y • Cardiac Mask Tool to mask extracardiac Display Gated Stripe Strip ... Tc99m Tc99m Tc99m *01.01.1969, M. 39Y *01.01.1969, M. 39Y HH Stress [Stress CTAC and Scatter] Stress [Stress CTAC and Scatter] Stress [Stress CTAC and Scatter) activity for improved cardiac Functional Fused 2x3 Fused Hybrid 3x3 4D 4D Fused RA com PRH RA 2×3 + M ... + Movie Axial 3x ... Functio ... 1x3 + ... 1 cm 1 cm MPR MPR MPR SL min SL AL min SPC 6.6 SPC SL min normalization and localization Cardiac AC Cardiac 6,6 90 % SPC NAC 0 % 6,6 90 % O 08 Mask R Localize Series ALF HAL HAL MI Cardiology Reading DEMO_Cedars_Symbia_Cardiac, EU DEMO_Cedars_Symbia_Cardiac, EU DEMO_Cedars_Symbia_Cardiac, EU Tc99m Tc99m Tc99m • Cardiac FAST Ranges* can generate short *01.01.1969, M, 39Y *01.01.1969, M, 39Y *01.01.1969, M, 39Y Rest [Rest CTAC and Scatter) Rest [Rest CTAC and Scatter] Rest [Rest CTAC and Scatter] axis result images without the need for RA PRH RA 1 cm 1 cm 1 cm IMPR MPR RA IMPR AL reconstruction for loading in other SL SPC min SL SPC min SL 6,6 90 % SPC min 6,6 90 % 6,6 90 % Findings O 96 0 % o cardiac applications ALF HAL HAL DEMO_Cedars_Symbia_Cardiac, EU DEMO_Cedars_Symbia_Cardiac, EU DEMO_Cedars_Symbia_Cardiac, EU Tc99m Tc99m *01.01.1969, M, 39Y *01.01.1969, M, 39Y *01.01.1969, M, 39Y Stress [Stress No Correction] Stress [Stress No Correction] Stress [Stress No Correction] RA cm PRH RA 1 cm 1 cm Printing MPR MPR SL SPC min IMPR SL A 6,6 min min SPC 6.6 SL SPC 6,6 82 % o ON ON *Dynamic PET data not supported 67 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Cardiology SIEMENS Healthineers New Configuration and Relaunch Option • Cardiac Configuration possibility Send only short axis series to the cardiac MI Cardiology Reading analysis applications was added to QBS QGS LO 4DM OPS MBF Cedars Cedars Relaunc configur .. improve the loading performance in cases where transverse and short axis Configuration × reconstructions are present • Cardiac Application Relaunch option Send only short axis series to the cardiac analysis applications allows to restart the cardiac analysis Note : Transverse data will be used if a corresponding short axis series is not available application that is currently displayed on the screen. This might be helpful to Launch cardiac analysis applications on secondary monitor accommodate late arriving data Apply Close 68 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 MI Cardiology SIEMENS Healthineers New Version of syngo.MBF VB20 The new version of syngo.MBF VB20 is Cardiac_MBF_Dyn_1_NH3 X 01.01.1943 M NH3 available with an enhanced feature for No Database myocardial blood flow quantification H3 : 067Y : 1/1/43 : M : Unknown BMI : PET/UNAM AC) : 3/29/10 16:29:20 : Radionuclide Total Dose 370.0 MBq Advanced Options HLA apex VLA ant 109690 High Motion Correction • Normalize by Rate Pressure Product (RPP) [ Stress Rest provides the function to normalize the rest Residual Activity Correction lat sep lat base apex O Stress flow quantification results and thereby the ORest reserve by means of the product of the 2] Normalize using Rate Pressure Product Frame E Frame E Frame E 00:04:00 00:04:00 Resting Heart Rate bpm 360s base 360s inf 3605 33938 heart rate and the blood pressure Resting Systolic Blood Pressure mmHg 3/29/10 16:10:15 : Radionuclide Total Dose 370.0 MBq Rate Pressure Product HLA apex VLA 75274 Rate Pressure Product Threshold 8000 Edit Please enter the resting heart rate and blood pressure lo proceed or de-select Normalize using Rate Presauma Produc lat sep lat base apex Frame E Frame E Frame E 00:04:00 00:04:00 00:04:00 360s base 360s inf 360s 15055 Cancel 69 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 SIEMENS Healthineers MI - News & Improvements PEPconnect 70 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 PEPconnect: Your Smart Connection to Knowledge SIEMENS Your Personalized Education Plan, the central point for education Healthineers SIEMENS ... Healthineers PEPconnect Explore Search Content and Groups In English | Log in / Register - syngo.via VB30 Nuclear Medicine - PET Applications Type Of: All- Language: English - Configurations: None Selected . Filter By Title: Enter text PEP connect All Learning Activities VB30 Delta - Nuclear Medicine MM Oncology Layouts VB30 MM Oncology Tools VB30 MM Oncology for MI: MM Oncology for MI: Hybrid MM Oncology for MI: MM Oncology for MI: MI Cardiology (syngo.MBF) (PET & SPECT) Online Quantification VB30 Gating VB30 Visualization / Image Fusion OncoBoard VB30 VB30 Training VB30 Videos in 5 0 106 00 Add To Plan Add To Plan 047 00 Add To Plan 45 00 Add To Plan 023 00 Add To Plan Add To Plan 0 27 Add To Plan 0 38 90 Add To Plan languages MI Neurology Basics VB30 MI Neurology-Database MI Neurology-Striatal DE MI Neurology-Subtraction MI Reading Basics VB30 Comparison VB30 Analysis VB30 VB30 New VB40 Delta Online Training Welcome to the syngo.via VB40 delta online training. Add To Plan 0 37 @1. Add To Plan 0 27 00 Add To Plan 01500 Add To Plan 38 00 Add To Plan In this training you will learn about new features and syngo.via VB30 Nuclear Medicine - SPECT Applications functionalities of the syngo via VB40 software version that covers Molecular Imaging (MI) / Nuclear Medicine Type Of: All- Language: English - Configurations: None Selected - Filter By Title: Enter text (PET & SPECT). All Learning Activities Help VB30 Delta - Nuclear Medicine (PET & SPECT) Online EMM Oncology Layouts VB30 EMM Oncology Tools VB30 MM Oncology for Ml: MM Oncology for MI: MM Oncology for MI: EMI Neurology Basics VB30 MI Neurology-Database Quantification VB30 Visualization / Image Fusion OncoBoard VB30 Comparison VB30 Training VB30 .syngo.via VB30 Online Help - Which's HEN? 0 106 00 Add To Plan Add To Plan 047 00 Add To Plan 9 45 00 Add To Plan Add To Plan Add To Plan 9 28 00 Add To Plan 037 01 Add To Plan Go to: www.siemens.com/pepconnect 71 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 PEPconnect: Your Smart Connection to Knowledge SIEMENS Your Personalized Education Plan, the central point for education Healthineers SIEMENS Healthineers' ... PEPconnect Explore Search Content and Groups English Log in / Register - syngo.via VB30 Nuclear Medicine - PET Applications Type Of: All - Language: English - Configurations: None Selected - Filter By Title: Enter text PEP All Learning Activities connect VB30 Delta - Nuclear Medicine MM Oncology Layouts VB30 DE MM Oncology Tools VB30 MM Oncology for MI: EMM Oncology for MI: Hybrid Training Quantification VB30 Gating VB30 MM Oncology for MI: DE MM Oncology for MI: Visualization / Image Fusion OncoBoard VB30 MI Cardiology (syngo.MBF) (PET & SPECT) Online VB30 VB30 Videos in 5 OIC languages 0 106 00 Add To Plan Add To Plan 047 00 Add To Plan Add To Plan 0 23 00 Add To Plan Add To Plan 27 00 Add To Plan 0 38 00 Add x plan MI Neurology Basics VB30 MI Neurology-Database MI Neurology-Striatal MI Neurology-Subtraction Comparison VB30 Analysis VB30 MI Reading Basics VB30 VB30 O28 00 Add To Plan 0 371 Add To Plan 0 27 00 dd To Plan 015 00 Add To Plan 38 00 Add To Plan syngo.via MI Workflows syngo.via MI Cardiology Applications VB50 Delta Online Training, Part 1 VB50 Delta Online Training, Part 2 Help In this training you will learn about new features and functionalities of the syngo.via VB50 In this training you will learn about new features and functionalities for the Cardiology software version that covers Molecular Imaging (MI) respectively Nuclear Medicine (PET and Applications Cedars Sinai Cardiac Suite 2017 and Corridor 4DM 2018 available for the SPECT). syngo.via VB50 software version. syngo ula 1 2 ............................... 3 .......... 4 1 2 ........... 3 4 ............... 5 Learn more about Become familiar with Learn more about Learn more about Clinical and functional General enhancements Clinical and functional Clinical and functional Clinical and functional further developments the new routine MI further developments in further developments enhancements of of Cedars Cardiac Suite enhancements of enhancements of enhancements of in MM Oncology General workflow MI Neurology in MI Cardiology Cedars 2017 QPS/QGS 2017 Cedars 2017 CFR Cedars 2017 QBS Corridor 4DM 2018 Master Template HOOD05162003052540 | Effective Date: 26-Nov-2019 Master Template HOOD05162003052540 | Effective Date: 26-Nov-2019 Go to: www.siemens.com/pepconnect 72 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 PEPconnect: Your Smart Connection to Knowledge SIEMENS Your Personalized Education Plan, the central point for education Healthineers SIEMENS Healthineers PEPconnection SIEMENS Healthineers Explore Search Content and Groups M My Activities My Plan Groups Transcript AB Medical Imaging and Therapy Explore Search Content and Groups Advanced Visualization and Imaging IT (syngo)|Computed Tomography| Digital Marketplace Magnetic Resonance Imaging|Mammography|Nuclear Medicine Technology - PET|Nuclear Medicine Technology - SPECT Ultrasound Angiography|Mobile C-arms nexaris Therapy Suites| Radiation Therapy X-ray Products Advanced Visualization and Imaging IT (syngo) syngo.via syngo Dynamics - CVIS syngo Virtual Cockpit syngo.plaza - PACS Type Of: Job Aid - Language: English - Filter by Module/Version: None Selected EN EN EN All syngo.share syngo.via syngo.via Clinical Applications Virtual Classroom EN EN EN General Video Nuclear Medicine Applications syngo.via VB20 syngo.via View&GO Online Training EN EN Gen Job Aid Itm & Features syngo.via Clinical Applications Type Of: Al - Language: English - Filter by ModuleVersion: None Selected . Filter By Title: Enter text OpenApps User Guide Job General Malcar Mediche Technology . PET| Nuclear Medicine Technology . SPECT Aid General Als.Paper .. Cinematic White Paper.Increasing the value of Radiology throug === 0 227 2 Ads Ta Plan Add To Pra Add To Plan Nuclear Medicine Technology - PET Management of Epilepty with gynoo.via Detabaco Neuronalyet In cyngo.via Technology ALPHA tantiparametric PET Butte techniques for CT - based PE White paper - Tips & Tricks: White Paper - HD-Chest Amplitude Based Respiratory Clinical Advances with White Paper - Cardiao wormparicon In Ml Neurology attenuation correction BUY abross technologies Using EQ.PET to Mescure Aproct Multiple Technologies Bating for PET FlowMotion Technology! Positron Emiccion Tomography: Myocardial ... Nuclear Medicine Applications -2 - --- ® 20 Add To Pra 6 20 0 Add To Man 9 14 00 12 00; Add To Plan Add To Plan Add To Man Add To Para Add To Plan Add To Pra Add To Man Organ Processing Workflow Organ Processing Workflow Nuclear Medicine Technology - SPECT Building: Part 1 Data Selector Building: Part 2 Job Aid Job Aid Management of Epllepty with Comparison In MI Neurology workflow Mi Neurology EXPECT: a clinical overview Characteristics of the Agourate, reproducible, and ET performance in SPECTICT Technology THOHEFHI .... .+ A 9 14 80 Add To Pla Add To Plan Add To Plis Add To Pias Add To Plan = = 14 00 Wionion incass Go to: www.siemens.com/pepconnect Add To Plan Add To Plan 73 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 HOOD05162003046557_Unrestricted © Siemens Healthineers, 2019 SIEMENS Healthineers MI - News & Improvements Innovations 74 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 syngo.via a Universal 3D Reading Solution SIEMENS Innovations Healthineers MI Workplace Education Plans WP syngo.via Open Apps* WebViewer* Annual Review and Customization' Education and Skills Assessment2 PEPconnections PEPconnections PEPconnections UpSkill Optimization & Consulting UpSkill Optimization & Consulting UpSkill Optimization & Consulting Remote Assist Remote Assist Remote Assist L Server Clinical Workshop Classroom Training XL Server Tailored Hands-on Tailored Hands-on PEPconnect PEPconnect PEPconnect Hand-over Training Hand-over Training Hand-over Training GAIN GROW LEAD ........... Clinical Applications syngo.via Virtualized Frontier Server Our Expertise Frontier Platform Our Education Plans GAIN . GROW. LEAD prototypes HW Infrastructure Frontier** Your needs Your Plan *The application syngo.via WebViewer is not for diagnostic viewing/reading on mobile devices in the US. *syngo.via and syngo.via OpenApps are not yet commercially available in all countries. Due to regulatory reasons, its future availability cannot be guaranteed. 75 Please contact your local Siemens Healthineers organization for further information and availability outside these countries. **For research use only. Not for clinical use. 2 Requires specific agreement with Siemens. Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 New “CT Pneumonia Analysis“ Prototype SIEMENS Healthineers Reacting to the severity of the current situation battling COVID-19, syngo is A SOMATOM Forc releasing a trial to our “CT Pneumonia Analysis” prototype free-of-charge to all our syngo.via users* R 200 mm- • Prototypes like these normally require the user to have purchased access to syngo.via Frontier – but we are entirely waving that for this prototype which is freely available on the Digital Marketplace through syngo.via OpenApps until 30 N 1200 November 2020 • syngo.via Frontier users can get regular, unlimited access to this application through the syngo.via Frontier Prototype Store • Siemens Healthineers customers who do not have a syngo.via can gain access using the AI-Rad Companion on the teamplay digital health platform *Users need at least syngo.via VB30A to access the Siemens Healthineers Digital Marketplace. syngo.via, the CT Pneumonia Analysis prototype, and the Digital Marketplace are not yet available in all countries. Due to regulatory reasons, future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further information. The CT Pneumonia Analysis prototype is for Research Only. Not for Clinical Use. 76 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021 SIEMENS Healthineers Please note that the learning material is for training purposes only! For the proper use of the software or hardware, please always use the Operator Manual or Instructions for Use (hereinafter collectively “Operator Manual”) issued by Siemens Healthineers. This material is to be used as training material only and shall by no means substitute the Operator Manual. Any material used in this training will not be updated on a regular basis and does not necessarily reflect the latest version of the software and hardware available at the time of the training. The Operator's Manual shall be used as your main reference, in particular for relevant safety information like warnings and cautions. Note: Some functions shown in this material are optional and might not be part of your system. Certain products, product related claims or functionalities (hereinafter collectively “Functionality”) may not (yet) be commercially available in your country. Due to regulatory requirements, the future availability of said Functionalities in any specific country is not guaranteed. Please contact your local Siemens Healthineers sales representative for the most current information. The reproduction, transmission or distribution of this training or its contents is not permitted without express written authority. Offenders will be liable for damages. All names and data of patients, parameters and configuration dependent designations are fictional and examples only. All rights, including rights created by patent grant or registration of a utility model or design, are reserved. Copyright © Siemens Healthcare GmbH 2021 Siemens Healthineers Headquarters Siemens Healthcare GmbH Henkestr. 127 91052 Erlangen, Germany Telephone: +49 9131 84-0 siemens.com/healthineers 77 Effective Date: 05/05/2021 | HOOD05162003191471 Unrestricted © Siemens Healthineers, 2021