syngo.via Neuro 3D Workflow (VA30)

syngo.via Neuro 3D Workflow (VA30) 1. Functions of Neuro 3D workflow:  Registration of the morphology, fMRI experiment and tensor images  Combine data from different days  Simultaneous visualization and post-processing of the functional and DTI data  Processing up to four fMRI experiments simultaneously  Utilization of 2D or 3D morphology images for DTI reference and creation of multiple Tractography VOIs  Time course evaluation of fMRI  Flexible image exporting tools 2. MR Neuro 3D Workflow: a. Open the patient using “assign workflow” or “view as read-only with” to the MR Neuro 3D workflow  Open the patient study once the workflow state is ready to read Last Name - * neuro* Date of Birth Modality MM Basic + -. MM Basic Compare Study Date and Ti. Study Description Accession Number MM Onco + CT Bone Workflow State Workflow Description Patient Name Date of Birth Modality St MM Onco + CT Vascular ription AZ All> > MM Oncology Adv Neuro, DTI&Bold LH MM Reading MR_Neuro_Perfusion_A_AVM Open MM Research Frontier CATION mMR General MR_Neuro_Perfusion_Ae_Stroke View as Read-Only MR Abdomen MR_Neuro_Perfusion_TaTS_Strol View as Read-Only with . MR Angio MultiStation sion MR Neuro Perfusion_V_Tumor Bion Neuro (Re-)Assign Workflow Template ... MR Angio SingleStation MR Angio TimCT ced applications ... Neuro Bo Group and Assign Workflow Template ... MR Angio TWIST ced applications. Cancel Workflow for Manual Reassignment MR Basic Cancel Procedure MR Breast MR BreVis Prevent Archiving MR Cardiac Analysis Delete MR C-Spine Protect from deletion MR Head Remove deletion protection MR Hip MR Knee MR L-Spine MR Neuro 3D Adv_Neuro, DTIBold_LH MR Neuro Perfusion Data MR Neuro Tumor Instance Number ~ Image Type Instance Creation Date ... Archiving Stat ... MR Onco Brain MR Onco Liver Segmentations MR Neuro 3D, 1, SEG MR Onco Multi-Region PDF Reports, 1, OT Results MR Neuro 3D, 2, MR MR Onco TimCT ep2d_diff_mddw_20_p2_TENSOR TRACEW MAP_BValue_1000, 1, MR MR Prostate ep2d_diff_mddw_20_p2_TENSOR_ADC_MAP, 1, MR MR Shoulder ep2d_diff_mddw_20_p2_TENSOR FA MAP, 1, MR MR Spectro MR Tissue4D DICOM MR TMJ MR T-Spine MR Whole Spine 3:53 PM  Note: If the patient folder contains many series such as 3D morphology, tensor, and BOLD data, opens the patient using “View as read only with” to load the data faster. When opening a patient, wait until the progress bar has stopped prior to proceeding with post-processing. SIEMENS www.usa.siemens.com/healthcare 782 Effective Date: 09/06/2016 Page 1 of 10 b. Overview of MR Neuro 3D  MR Neuro 3D workflow processing steps: o Alignment: Image based registration of morphology, fMRI experiments, and tensor data o Image Selection: Selection of structure, field map and tensor o fMRI: Simultaneous 2d/3D visualization of multiple statistical maps o Tractography: Visualization and manipulation of Tractography data o Time Course Evaluation: Show 4D signal time curves for VOIs o Export: Export predefined orientations in various formats A MR Neuro 3D Ad-Hoc task to MR Neuro 3D workflow - MR Neuro 3D Alignment Image Selection fMRI Tractography Time Course Evaluation Export c. Registration for morphology, fMRI and tensor images MR Neuro 3D Alignment Reference series 12/1 202011 Gp2d pace moco lefthand RLA 2pad die mody 20 po TENSOR SL 1.0 SL 10 Available target series TE 7 Available fusion palettes Palettes Advanced Parution STUDYID E Hiend 10:53:57 AUF Home all Auto Alignment All Findings Navigator HLA 23 EL 1.0 4:02 PM SIEMENS www.usa.siemens.com/healthcare Page 2 of 10  MR Neuro 3D performs an automatic registration of the functional and morphology images based on the signal intensity in six dimensions. A visual alignment may also be performed by the user. If an auto or manual adjustment is made, the field map MR Neuro 3D ‘ ‘ Zoom/Pan Alignment 3D Reference Point :: Windowing CURRENT HFS Select one target Movie STUDYID 1 epad pace moco Legrand Cp2d off modw 20 p2 TENSOR Automatic Alignment 53:57 AM Visual Alignment 1cm Scroll Select the visual alignment Alghment Overviewr Fa to Segment A To view all targets TH WOOD TES SL10 TE 1 3 SL 10 MPA FUE ON TOMA BPC10 MPA FUBION BPC10 AN 12.0 Biend Image Selection CURRENT CURRENT -LPH HAH STUDYID 1 MIT AM Findings Navigator -RA TE 50.0 MPA THICK- HP SPF114 FI Motion correction of fMRI TR 600 D TETE SL 1.0 MPA FUB ON : 19 ANDMORE SPC 10 AN 4:03 PM Select one target to view more details about the alignment or to perform a visual alignment d. Image selection for morphology, field maps and tensor data MR Neuro 3D MR Neuro 3D Alignment t1_spc_sag_p2_Iso_11.0.latest Released when MR Neuro 3D Targets selecting one step Alignment ep2d_pace_moco lefthand ep2d_pace_moco lefthand below it Image Selection ep2d_diff_modw_20_p2_TENSOR Structure 11_spc_sag_p2_iso_11.0.latest Alignment Overview Select different structure, field map Field Map and tensor No Field Map Palettes Edges fMRI Blend Tractography Time Course Evaluation Export Image Selection Dim while in alignment step Remaining Images SIEMENS www.usa.siemens.com/healthcare Page 3 of 10  Note: The image selection step is dimmed when performing the alignment. This step will be released after selecting a step below it. e. Processing the fMRI MR Neuro 3D Image Selection TMRI Function ep2d_pace moco_lefthand Up to four different experiments can be All the experiments have the viewed in the Function list. Use the eye same overlay color icon to view/hide the experiment. The primary experiment will have a Each experiment has a different . Primary determined color palette, while the overlay color Secondary secondary experiments will all have another determined color. none Solid Red Synchronize the color value Set different color for experiment. Shift the between active and rest phase -15.00 -4.00 4.00 15.00 slider to adjust the activation area. Maximum translation of fMRI Bi -00.21 mm max -00.26 deg max Maximum rotation of fMRI measurement measurement Blend The percentage of activation area overlay to the morphology Icons in fMRI Step MR Neuro 3D MPR MPR image Selection IMRIE Function enla pace mode lemina 1 1.10 MORTUCION: p2 -15.00 400 3 Function Pregartias Blend opde pace moco lefthand CURRENT Findings Navigator All Activation M 3 2 Derauth Cancel 83 4 4:13 PM MPR [9] Floating MPR VRT+ clip plane 1 Control the "eye" icon and display mode to determine which experiment to display 2. Select the head mask to reduce the noise outside the brain. 3. Set the interpolation and clustering size in the function properties. 4. Snapshot for the image with result. SIEMENS www.usa.siemens.com/healthcare Page 4 of 10 f. Tractography MR Neuro 3D All diffusion tracts is calculated A Diffusion Trach during the work flow assignment Active the interactive settings Mesi The preset of the tracts setting, and mode to draw seed point can change you want Tractography VOI + Tractography plane Tractography VOI shrink to activation + VOLT B not A A or B Group A and B A and B A not B Save with user setting criteria Save with user setting criteria with a new name Time Course1 Save with default criteria Tractography tools MR Neuro 3D 173 Tractography Display all the tracts with default setting HFB HF'S Al Diffusion Tracts Properties IN STRUCTURE STRUCTURE STUDYDI Statistics Regenerate -AL -RA Settings A TR TEN SL 10 TE 7.3 SL 1 0 BPC10 MPA FUSION BPC10 AN MPR+Tracts MPR+Tracts Time Course Evaluation CURRENT STRUCTURE STUDY DI Findings Navigator -RA F TR 600 D TE J.F EL 10 C BPC 10 4:15 PM MPR+Tracts VRT+Tracts All diffusion tracts will be calculated during the workflow assignment and provides an overview of the tracts and tract direction in the brain. Right mouse click to view settings and regenerate the tracts SIEMENS www.usa.siemens.com/healthcare Page 5 of 10 Diffusion Tract Bundle Properties Tract Length Tract Length 50 - 4095 mm Properties: Change the visualization of the tracts. Color Solld Color Tract length: defines the length of tracts . Direction Encoded Color Color Palette Hot Metal Color: define the color for the tracts Graphics: Display the tracts as a line or tube Graphics with different radius. Line Tube Tube Radius 0.6 mm OK Default Cancel Diffusion Tract Bundle Statistics All Diffusion Tracts Statistics: Display the diffusion tracts bundle statistics. Value Number of Tracts 3204 Mean FA 0.4714 Mean Dintusivity 0.0027 Statistics of the tracts bundle tadal Ciftusivity 0.0022 Tract hy Parameters Parameter Va Tract Length(mnm) 50 - 4095 Send points per vouell math 1 Andle Threshold Parameter which use to calculate the tracts FA Threshold 02 Send Points Cancel Lailusion Trad Bundde Settings Deisul Al Dertusion Tracts Tractography Peruneters Tract Length Send ponto pois Angle Thereghold 120 Diffusion tracts can be regenerated after Visualization Parameters settings have been changed. Color Direction Encoded Color Tube + -7 SIEMENS www.usa.siemens.com/healthcare Page 6 of 10 MR Neuro 3D Tractography HY CUSENT HFER Invoke the interactive mode to draw seed point as you want STUDY DI Settings Default Edit the user setting RA TR 650 D VOL1 TE 13 SL 10 Select the user setting to calculate the tracts Time Course Evaluation CURRENT CURRENT -a Cure - und Fusion on Findings Navigator RA 83 TETT EL 10 TE Right mouse click on the EPGID seed point to hide the seed point 4:19 PM Processing steps in interactive mode: 1. Select the interactive mode to draw the Tractography VOI 2. Draw the seed point using the VOI, plane or the VOI shrink to the activation area. Shape the Seed point to the tumor or the anatomy. 3. Use different Boolean type filter to display specific tracts. 4. Display the tracts with brain mask, floating MPR, etc. 5. Save the tracts with different setting. A or B A and B A not B B not A O O The tracts run The tracts run The tracts run The tracts run either through through through A through B A or B A and B Tracts running Tracts running through B are through A are not displayed not displayed Boolean type filter SIEMENS www.usa.siemens.com/healthcare Page 7 of 10 g. Time course evaluation MR Neuro 30 Time Course Evaluation + Experiment list used for evaluation The same features as fMRI step Bigrid fMRI VOI + + Delete all evaluation VOI/Pixel Expert fMRI voxel- Overview of Time Course Evaluation MR Neuro 3D Time Coursa Evaluation Funktion word pade moto lefthand [ cpodepsoe moço lefthand TR 600D TEJ RAH MPA FUSION A MPR/Activation area TR 1000 0 -15.00 400 UPA DOCHTENU NONEND 4.00 15 00 AUFB Blend Original BOLD Export Mean Curve TEVE MPRFUSIONLE H Measurement paradigm Findings Navigator - Motion correction 4:25 PM Evaluating the quality of the fMRI experiment: Does the time curve follow the paradigm? Does the time curve have the expected increase and decrease? Does this correspond to the motion correction? SIEMENS www.usa.siemens.com/healthcare Page 8 of 10 MR Neuro 3D Time Course Evaluation STUDY O CURRENT Funchen 1 epid pape moco lefthand idee meco lefthand TUDY DI Cord pace moco lefthand TER TA Het Muti 05.00 4.00 4.00 1500 STUDY DI Diend Export MIPER FUE Th Findings Navigator 53 ELID 4:27 PM Manual steps: 1. Select the fMRI VOI/voxel to draw a VOI or pixel on the activation area. 2. Adjust the position of the VOI and select shrink to activation. 3. Access the mean curve with the measurement paradigm, and check the quality with motion correction. 4. Right mouse click on the VOI/Voxel and create the finding. User can discard the measurements which have a lot of motion or where the patient didn't follow the measurement paradigm in order to verify the quality of the BOLD experiment.| h. Export the result MR Neuro 3D Tine Course Evaluation Select the segment to be exported; user can select one, or two or all of the three segments Add image comment on Image Comment the export result Honpooni Series name after export Format to be exported: Fused (MR RGB) Native (DICOM MR) Multi-label Native (DICOM + Export MR) SIEMENS www.usa.siemens.com/healthcare Page 9 of 10 MR Neuro 3D Tractography Time Course Evaluation HFS Expert 17144-199 Image Coriment pe Seriey Descripton TH WOOD 5110 TE IT Range Fused MPA FUSION TO Image Type INCOM MIT Remaining Images HFB CURRENT HFB STUDY D Findings Navigator tem TH 600 TETE 5L 10 TE JF BPC 10 4:31 PM Manual steps: Select which image orientation that should be exported. 2. Select the image type to be exported. 3. Select export. MR Neuro 3D Tractography Time Course Evaluation Image type: Fused (MR RGB): one fused result per orientation selected. Saved as a secondary capture image -used for PACS Image Comment Native (DICOM MR): one result series per series-used for fusion with CT, etc. Range Series Description Range Fused Multi-label Native (DICOM MR): one fused result series per image Type orientation - used for surgical planning. Fused (UR RGB) Fused (MA AC3) Remaining Images i. Complete the patient to send the results to PACS SIEMENS www.usa.siemens.com/healthcare Page 10 of 10