syngo.via VB30 MI Neurology-Striatal Analysis e-Clip

Getting Started I Fusion to CT I Fusion to Template I Analysis I Editing ROIs I Database Creation I Adding Patients to a Database  I Managing Databases I Reference Brain Selection I Screen Captures .

Striatal analysis can quantify scans for SPECT. DAT scan and pet. The striatal analysis workflow allows the users to create their own database of normal ratios. An additional step is provided to compare current patients as striatal ratios against an age and sex corrected normal population. Before using the striatal analysis software, be sure to perform a visual read of the patient data set. In striatal analysis, the workflow steps are listed in the upper left corner, Fusion to template analysis and Fusion to see T if a see T is available. The Fusion 2 template workflow step will fuse the patient data set to the ratio analysis template. To manipulate the images, use the toolbar on the top of the screen. To scroll through the images, use the image sliced text in the lower right corner of the segment. Click and drag the text or down to scroll the scroll wheel also scrolls through the images. To pan or zoom, use the icons in the upper left corner. To view the Fusion, click the transparency icon and move the mouse pointer to the left or right to view the registration. To adjust the registration manually, click the manual Fusion icon. To manually fuse the data set, click and hold to pen the patient data set. To rotate their data set, click the green circle. To revert back to automatic Fusion, click the revert to automatic Fusion icon. The Fusion can also be based on a pet to PET or CT to see T. To use a different method, click the icon and the automatic Fusion begins. A status bar is provided in the lower right corner. The analysis workflow step provides a view of the three Axis planes Australia. It'll tab as well as a region of interest quantification table. The table provides the ratio, mean maximum and average ratio for the regions of interest. The normalization region is currently set to Osip, it'll lobe. To change the normalization region from the list, select the normalization region. The regions of interest are currently all highlighted and displayed on the data sets. To visualize more regions of interest from the normalization region selection list, select the appropriate regions. Note normalization region cannot be changed if a database is selected for analysis in the striatal workflow. For both SPECT and pet. The striate leroys are set automatically. By default they are unlinked. To adjust a Roy click edit Roy, click and hold to Pan the Roy. To rotate the Roys, click the circle. To link the striate leroys, click link left and right Roy for editing. To display the striatal box, click striatal box. To go back to the automatic positions, click the reset striatal Roy. Striatal analysis also provides the opportunity to manage databases by creating custom databases, editing custom databases and reviewing custom databases. To create a new database, click the databases list in the menu and select create new database. A dialog box appears asking for information on the database. Enter the database name, a description, and select the settings. The proportion of the brightest voxels determines which voxels inside the selected normalization region are used when normalizing the subjects in the database and the patients to be compared to the database. Click the create icon. Once all data is entered. To add a patient to the database, click the databases list an select add current subject to database. The activity is grayed out if the Fusion 2 normal workflow step has not yet been passed. Select the appropriate database that the patient should be added to. A dialog box opens. Confirm that the information is correct and click add. A dialog box appears indicating that the subject was successfully added to the database. To manage the databases from the databases List, select manage databases. A dialog box appears listing all the databases available in database comparison. To view a database, select the database and click the view icon. The View Database feature provides basic information such as the number of patients and age range. Two sets of images are also provided. The main uptake shows the main uptake of every voxel in the database. The mean of all subjects that compose the database. The standard deviation shows the standard deviation of every voxel to the mean. To close the overview, click close. To edit a database, select a created database and click edit. The title and description may be edited and subjects can be removed from the database. Once editing is complete, click OK. Created databases can also be deleted by selecting the database and clicking the delete icon. A dialog box appears asking you to confirm the deletion. Click OK to delete the database. Once a database is created the next time the striatal analysis software is started, the reference brain selection dialog box opens and the user can choose the custom database. The analysis workflow step provides a graph to illustrate the patients deviation from the custom database. The table is updated with patient reference values and the Z score. Note, no graph is shown in pet striatal analysis. To create a snapshot of the screen, click the snapshot screen icon. The snapshot is added to the key images as well as to the findings navigator. To create a snapshot of an individual segment, click the required segment and click the snapshot segment icon. For more information on ratio analysis and the tools and functions available, click the Help list an select the help file to open the online help. To view the snapshots or to complete the examination, enter the case Navigator by moving the mouse pointer over the left Arrow key. To view a snapshot, double click the icon in the findings Navigator.

abc Annotations SIEMENS SIEMENS . n to Template Scale: FOV: Scale: 0.52 Scale: Scale: 0.5 21.2x26.2cm - Scenium_DaTSCAN2 0.5 FOV: 21.2x26.2cm scale: 0.5 FOV: 21.1x26.2cm scale: 0.5 FOV: 21.2x26.2cm FoV:21.2x26.2cm - 0.5 FOV: 21.1x26.2cm scale: 0.5 FOV: 21.2x26.2cm - • 0.5 FOV: 21.2x26.2cm Scale: 0.5 Scale: FOV: Scale: 0.52 Siemens Healthineer Siemens Siernens Siemnens server: 146.254"3144 Server. 146254.133144 Server. server: server: 146.254"3144 server Server. 146254.133144 server '4634133144 Server. Server. 14629133.144 server 1-123-Datscan BRAIN SPECT Help 1-123. Datscan Heatthineers• M 072M d. BRAIN SPECT 1-123-Datscan I-123-Datscan M072Y M 072 Y M 072M L 109.2 109.2 103.1 NM: W 145.6 L 109.2 M072Y NM:W145.6L 109.2 M072Y NM:W 145.6 L 109.2 NM: W 145.6 L 109.2 NM:W 145.6 L 109.2 M072Y Neurology Analysis Striatal Analysis 1-123 FP abc Fusion to Template scenium DaTSCAN2 - scenium DaTSCAN2 • scenium_DaTSCAN2 Scale: 0.5 FOV: 21.2x26.2cm 0.5 21.1x26.2cm 0.5 FoV: 21.1x26.2cm - Scerium oarscAN2 DaTSCAN2 :s scale: 0.5 oarscAN2 scale: 0.5 Fov: 21.8x26.2cm scale: 0.5 FoV: 21.8x26.2cm Scale: 0.5 Fov: S scenium_DaTSCAN2 Sceniumn DaTSCAN2 Sceniumn DaTSCAN2 Sceniurn DaTSCAN2 -cenium DaTSCAN2 Scenium DaTSCAN2 Scenium DaTSCAN2 S scenium DaTSCAN2 BRAIN SPECT - scer,ium oaTSCAN2 scale: 0.5 M 072M NM: W 145.6 L 109.2 M 072Y Analysis scale: OS FOV: 21.2*26.2crn - scenum_oaTSCAN2 M 1-123FP M 072M 1-123 FP M 1-123 FP 1-123FP L123 FP L 109.2 W L 109.2 072Y 4. 1-123 FP Scale: Scale. Scale; • 0.5 FOV: 21.1*26.2cm scale: 0.5 f-ov: Scale: FOV: scale: 0.5 FOV: scale: FOV: Ml-123ÉP Sceniumn DaTSCAN2 Scenium DaTSCAN2 sceraum_DaTSCAN2 . scenium DaTSCAN2 BRAIN SPECT yew Annotations 1001s Qatabases BRAN SPECT Fusion to Template Striatal Analysis Neurology Analysis M 1-123FP M 1-123 M FP M 1-123 FP M 1-123 FP 1-123FP 1-123FP Neurology Analysis NM: W 145.6 L 109.2 M072Y View Annotations 1001s Qatabases View Database NM: W 145.6 L 109.2 NM:W145.6L 109.2 M NM: L NM: W 145.6 L 109.2 Yiew Annotations Annotations Yiew Annotations Qatabases Annotations Qatabases Annotations QatabaseS Annotations Tools Qatabases Annotations Help Help Scale: 0.5 Fov: a IS BRAIN SPECT 1-123FP . Scenium_DaTSCAN2 Fusion to Template 0.0 0.5 :s OS M 1-123 FP M 1-123 1-123 FP Annotations Tools 'Pataba* Help scale: 0.5 FOV: 21.2x26.2cm M 072M M072Y NM: W 145.6 L 109.2 M Annotations Databases View Yiew Annotations 1001s Databases Yiew Annotations 1001s Qatabases View Annotations Tools Databases Yiew Annotations Tools Databases Annotations Tools Qatabases Help View Ml Neurology Annotations Tools Help Annotations Tools Qatabases Annotations Tools Help View Annotations 1001s Qatabases M 4. d. 4. 109.2 L 109.2 109.2 Show Annotations 1001s Qatabases BRAN SPECT 1-123-Datscan . sceniwr, DaTSCAN2 Fusion to Template Create New Database Create Database Help Reference Brain Selection Help Ml Neurology . •uisition Protocol... Color Maps View Annotations 1001s Qatabases Alt•-Q scenium_DaTsc.ÄU2 scale: 0.5 FOV: - uisition Protocol.. View Yiew BRAIN SPECT A123A10dine 1-123-Datscan Annotations 1001s Qatabases View Annotations Tools Databases Yiew Annotations 1001s Qatabases Help a is na is Ml Reading Color Maps View Database Edit Database scale: 0.5 Fov: 21.8x26. SPECT SPECT 1-123-oatscan 123-Datscan 123-0atscan Striatal regions. Striatal Analysis Create New Database About Striatal Analysis.. NM Ml Neurology BRAIN SPECT A123A10dine 1-123-Datscan scale: 0.5 Fov: 24.8 Analyses M J. M 072M d. scale: 0.5 FOV: 21.8' NM scale: row; Scale: 0.52 0.5 FOV: 21.2x26.2cm scale: scale; row; 0.5 rov: - scenum_oaTscgN2 :s scale: 0.5 21.0K26.2cm scale: 0.5 Scale: FOV: Striatal Analysis Neurology Analysis NM: w Images a is ages Database Name Test Database Settings Database Catieat Axial Mean SD Manage Databases Viewe Database Fusion to Template MI Reading Ml Reading scale: 0.5 FOV: 21.8' L 109.2 L 109.2 1209.2 109.2 109.2 - oaTSCAU2 BRAIN SPECT 1 BRAIN SPECT BRAIN SPECT 1-123-Datscan —23A10dine 1-123-Datscan .23A10dine 1-123-Datscan ine 1-123-Datscan BRAIN SPECT I-123-Datscan Striatal regions Striatal Analysis Striatal Analysis Striatal regions. Striatal regions Neurology Analysis '3Alodine 1-123-Datscan Striatal Analysis Striatal regions. Color Maps v' 2-3 FP NM: W 145 BRAIN SPECT A123A10dine 123-Datscan Alt+A Analyses Analysis Anatysis Anatys.s NM: W 145.6 L 109.2 Description Fusion to Template Please note that the learning material is for training purposes only! Regions of Interest - TSCAN2 Scenium _Da TS Scale; 0.5 FOV: Scale: FOV: 0.5 Fov: 21.1x26.2cm - Sceniurn DaTSCAN2 scale: 0.5 FOV: 21.2x26.2cm - FoV:21.2x26.2cm - Striatal Analysis S a TSCAN2 S a TSCAN2 sc T S CAN2 - DaTSCAN2 S a TSCAN2 scale: 0.5 FOV: 21.2x26.2cm - 0.5 FOV: 21.1x26.2cm • 0.5 FoV: 21.1x26.2cm _DaTSCAN2 - DaTSCAN2 :s 0.5 FOV: 21.2x26.2cm Scale: FoV: scale: 0.5 FOV: 21.1x26.2cm - scale: 0.5 FOV: 21.2x26.2cm - • 0.5 FOV: 21.2x26.2cm - scenium DaTSCAN2 sc eniu m_DaT SCAN2 Scenium DaTSCAN2 Sceniumn DaTSCAN2 :s Scale: 0.5 FoV: 21.1x26.2cm 0.5 FOV: 21.2x26.2cm scale: 0.5 FOV: 21.2x26.2cm Scale: FOV: Scale: 0.5 FOV: 21.2x26.2cm Scale: 0.5 Fov: 21.2x26.2cm scale: FOV: 21.8' scale: 0.5 FOV: 21.8' Neurology Analysis - Scenium_DaTSCAN2 scale: 0.5 FOV: 21.1x26.2cm scale: 0.5 FOV: w 14-5.6 L 109.2 scale: OS FOV: 21.2x26.2cm scale: FOV: NM Radiopharmaceutical 1231-FP-CIT M072Y -L M 072Y M 072M template: W 4.2 L 2.1 NM: W 145.6 L 109.2 NM: W 145.6 L 109.2 M072Y NM: W 146.6 L '09.2 NM: W 145.6 L 109.2 M w 4.2 L 2.1 M W 4.2 L 2.1 W 4.2 L 2.1 M 072Y M072Y M 072M 072Y M 072Y 072M NM:W145.6L 109.2 M scale: rov: W L 2.1 Template: W L 2.1 Template: W 4.2 L 2.1 W 4.2 L 2.1 W 4.2 L 2.91 2.1 NM: W 145.6 L 109.2 NM: W 145.6 L 109.2 M072Y NM:W145.6L 109.2 M M _/_ M J. M 4. J. 109.2 M072Y 109.2 M072V W 145.6 L 109.2 NM:W 145.6 L 109.2 NM: W 145.6 L 109.2 NM:W145.6 L 109.2 M NM: W 145.6 NM: W L 109.2 a is L 109.2 NM: W 145.6 L low Normalization Region Ratio to Normalization Region Primary Normalization region Occip M 072M M072Y L M W L 109.2 L 109.2 M - scenum_D8TSCAN2 072M Key Images Fusion to Template usion to usionto em ate usion to Tem late Fusion to Template BRAIN SPECT 1-123-Datscan BRAIN SPECT NM: W L 109.2 I-123-Datscan 1-123-Datscan Ml Reading Ml Reading MI Reading ROI NM:W145.6L109.2 - W L 109.2 L 109.2 - NM: W 145.6 L 109.2 NM: W L 109.2 W L 109.2 Patient Values Patient age: 72 is Manage Databases - oaTSCAN2 109.2 Show Neurology Analysis Database Name Testi Scale: 0.5 IOV: 21.1x26.2cm s Scenium DaTSCAN2 Color Maps Database Name Test Description Occipital 10be Occipital lobe Frontal lobe lobe . Show Show 1-123 FP 1-123 1-123FP M 1-123FP Database Name jest Age Range 72 - 72 1-123 FP 1-123FP 1.123 FP Database Name Normalization Region: •scale: you: Normalization Region Ratio to Normalization Region Scale: 0.5 Fov: - Scenium DaTSCAN2 usionto em ate Template: W L 2.1 Database Template Show usion to Tem late - Scen,ium DaTSCAN2 - Scenium DaTSCAN2 Scale: 0.5 Fov: 21.1x26.2cmn - Scale: 0.5 FOV: 21.1X26.2cm - Scenium Patient Left Anatysis Analysis Neurology Analysis Str Sex M M072Y NM: W 145.6 L 109.2 Scenium DaTSCAN2 Sceniurn DaTSCAN2 . scenium_oaTSCAN2 sScenium DaTSCAN2 - Scenium DaTSCAN2 Color Maps Striatal Analysis Occipital bbe Show Scale: 0.5 Scale: 0.52 Occipital lobe Occipital ioDe Occipital •obe Occipital Show Occipital ioOe lobe g Show . Show Show P123FP Key Images M 072M NM: W 145.6 L 109.2 M 072M Primary 1-123 FP Ref: Ml Neurology Regions of Interest Key I Key Occipital 10be NM Show 23 F p Axial Coronal Coroncal M 072M M072Y Template: W 4.2 L 2.1 Template: W L 2.1 Sagittal Sagitti Primary Occipital lobe Normalization Region: Oc Normalization Region: Frt Normalization region: Occipital lobe Normalization region Occipital lobe Normalization region Occip L 109.2 for Calculation NM Database Settings Analyses Fusion to Template Fusion to Tem late 1-123 FP Color Maps Regions of Interest Regions of Interest Images Key Images Images Slice 31M Slice Slice 41/109 1342:52 Slice 41/109 13:42:52 Slice 41/109 Slice NM:07xJul-2011 134252 NM:07-Ju1-2011 134252 13:42:52 NM: W 145.6 L 109.2 NM: W 146.6 L 109.2 NM:W145.6L 109.2 M uw.W146.6L 109.2 - W 145.6 L 109.2 145.6 L 109.2 - 109.2 L 109.2 3D Hybrid Vlevv 3D Hybrid Viewv 3D Hybnd View 30 Hybrid 3D Hy/b'id Vlevv Color Maps M 1-123 FP M 1-123 FP Transparency Normalization Region Ratio to Normalization Region Radiopharmaceutical: 1231-FP-CIT Ratio Radiopharmaceutical: Age Range: 72 - 72 Sex: M Name Lean Mean Database Smoothing NanE Mean Analysis Modality Radiopharmaceutical Age Range used as training material only and shall by no means substitute the Operator Manual. Any material used Sex Occipital lobe occipital lobe Occipital 10be lobe Show Striatal regions. NM 1-123FP patient age: 72 NM Database Cortical Cort' cal Striatal Struatal Strutal •cc I pital lobe Clobe _O_ NM _ß_ NM Database Database Corteal Mean Template Graph Caudate... Caudate. _ 168.0 168.9 204% Analysis a is View Images Database Coroncal NM Create New Database FWHM value (mm) Frontal lobe Name Mean Normalization region: Occipital lobe 733 133.1 patient M Smoothing FWHM value (mm): O Template Basal Ganglia SPECT [Read-onlY1 Other WHO MIHO Description Database: Test Database (72 72 Y) patient: M, 72 Y primary Scenium_DaTSCAN2 Scenium DaTSCAN2 suce Regions of Interest Key Images Brain Outline Corpus _ Corpys 1037 17625 176_2 3.76% 376% 325 2 25 Striatal Striatum Key Images Images cipital 10be Cipttal lobe Proportion of Brightest Voxels 100.0% Color Maps 231_Fp-ClT M072Y M 072M Primary 173.5 Template Basal Ganglia SPECT [Read-only] Template Basal Ganglia SPECT MIHO o -ggg 0-999 NM Other Corpus _ 110_1 110.1 1.0.1 109.2 239 a. Database Striatal regions. Normalization region: Occipital 10be Normalization region: Occipital 10be Plotted values: Striatum Striatal Normalization region: OCCiPital 10be Plotted values: 9tnatum patient Lett Patient Lett Patient Left Fusion Controls Corpus _ 1209.2 225 3D Hybnd View 3D Hyb'id Vlevv 3D Hybnid View corpuszz Color Maps Database corpus Corpus _ Corpus . 97.5 976.5 973.5 173_5 133.1 2.791 2.125 2.912 2.12 1680 o us Proportion of Brightest Voxels: 100.0% Coronal Mean Sagittal Mean Axial Mean Viewe Database View Database Coronal SD Coronal 3D Hybrid View Normalization region Occipital lobe Striatal regions. Transparency Slice 31191 Normalization Region Ratio to Normalization Region Name Mean Edit Demplete Template Basal Ganglia PET [Read-only] Template Other M/F,'O 0-999 Corpys 1762 125.7 109.2 376% 283 2.79 2_79 1-123 FP Lenticul 276.2 Viewe Database Occipital lobe Show Please select a radiopharmaceutical: Pons (flutemetamol) Color Maps Manage Databases 168_g 3D Hybnid View Coronal 133M 2.912 Patient Values Patient Values Reference Values corpus _ Template Show Lenticul._, Lenticul„. Lenticulm.. Lenticul... 0.02 1762 1209.2 1202 1342052 133.1 176.2 173.5 281 NM Template NM Occipital lobe Occipital 10be on: Occipital lobe Show Occipital lobe Database Coroncal Regions of Interest Name Mean Mean Ratio Cortical Key Ima Caudate, 733 mary visual cortex (AAL) 2.79 Ratio to Normalization Region Create New Database Ratio to Normalization Region Normalization Region Corpys 225 1037 NM Template Left Lenticul... Database Cortical Database Settings Database Cortical caudate caudate... Striatal I Striatal Strsatal 1680 LA The Operator Manual shall be used as your main reference, in particular for relevant safety information Left Mean ± 2 SD Right Mean ± 2 SD Left LA 11 Corpus . Striatal Reg ons of Interest Key Images Brain Outline Brain Regions of Interest Key Images Key I Regions of Interest Striatal Regions of Interest View Available Reference Brains for Selected Radiopharmaceutical: Database Settings Database patients 73.3 133.1 110.1 2.39 1.59 173.5 Modality Coronal Axial z-s Transparency Database patients 1.59 striatum Striatal 3.045- 2.12 304 3.06 ± 0.00 0.93 3.17 0.00 3.08 1342:52 Slice 3091 13:42:5S2 1342:52 1342:5S2 Slice 41/109 Striatal regions. The reproduction, transmission or distribution of this training or its contents is not permitted without Lenticul___ ROI 3.25 2.02 1037 225 Name Normalization Region Ratio to Normalization Region Nan-re Fusion Controls Available Reference Brains ror selected Radiopnarmaceutical: Age Range 3D Hybrid View Add Subject to Test Sex Age Range Coronal Slice 411109 134252 Slice Slice 41/109 caudate 325 3_25 3:13 Tools for Calculation and Analysis of Uptake Ratios of Stnatal Regions 176.2 1202 289 239 Normalization Region Ratio to Normalization Region Database Name Name Radiopharmaceutical h23 Normalization Region: Normalization region: Occipital lobe Ratio to Normalization Region Normalization Region Normalization region: Occip Slice express written authority. Offenders will be liable for damages. Template Basal Ganglia SPECT [Read-only] sc NM Axial Modality NM Radiopharmaceutical 938 1680 204 Corpus . 97 s Delete corpus . Putamen 283 283 2.76 2.839 2.791 2.91 201 291 287 ± 0.00 287 ± 0.87 Axial Database: Test Database (72 - 72 Y) Coronal Coronal SD C Mona' Sagitti Sagittal Sawitti 3D Hybrid View Normalization region: Occipital lobe orona OCCiPital 10be 134252 View Patient Values Patent Values Patient Val 1-123 FP Transparency 13.42:52 NM: 07-Jul-2011 Caudate._ Caudate. _ Striatal Regions of Interest 730 73.3 :07-Jul-2 Axial Slice 411109 Slice Slice 41/109 13:42 52 13:42:52 13:4252 1.59 1202 1762 2_73 1736 Occipital iobe Occipital lobe Show 0-999 Ratio to Normalization Region Normalization Region Ti•or Putamen Anterior Putamen Ansterior Putamen 0.87 2.72 3.085- Template Basal Ganglia SPECT MIHO Slice Patient Values Patient Left Values 1-123 FP 1.123 FP M 1-123 FP Corpus _ 376% 225 Scale: Right Graph Lenticul... 1736 9736 261 2.25 2.761 2834 2.81 Ratio to Normalization Region NM: W 145.6 L 109.2 W: W IW6L 109.2 NM: W 145.6L 109.2 W 145.6 L 109.2 w: W 109.2 NM: W L 109.2 NM: W L log.2 J. J. W L 109.2 W L *09.2 W L Normalization region: Occipital lobe Patént Val Scenium DaT Scenium DaTSCAN2 Scenium—DaT Scenium DaTS sex M Edit Normalization region Occipital lobe Normalization region: Occipital lobe Corpus _ 110M 120.2 Occipital lobe 289 Ratio to Normalization Region Normalization region NormalizatiOn posterior putamen Axial 2_79 2.76 2_76 NO NM NM Right Rig M information in this material contains general technical descriptions of specifications and options as well Striatum 1736 308 3_02 All names and data of patients, parameters and configuration dependent designations are fictional Add subject Striatal Igator igator 10 oo 00 40 Patient Values Patient Val Patent Val M 3_ Subject narne: Slice 55'10g Corpus _ - scenjum DaTSCAN2 Sceniumn DaTSCAN2 133.1 Slice M23FP Import Export Slice 31/91 13:42 Striatal Regions of Interest Slice 31'91 M 072 Y M 072M Information BRAIN SPECT Striatal I lobe Caudate... Caudate.. Striatum 3208 3.25 325 3.257 3.13 313 3.08 Antenor putamen Ratio to Normalization Region 1-123 FP 2257 1037 1037 176.2 2876 2.89 2.73 Asymmetry Measures Normalization region: Occipital lobe asures Right as standard and optional features that do not always have to be present in individual cases. Create and examples only. Caudate Credate Caudate. 325 3.04 3.17 3.13 3.02 2.84 3.08 281 283 291 0.01 0.07 2.839 07-Jul-2011 13:42:52 Left Findings Navigator Navigator Lenticul___ Lenticul.__. 261 Putamen Proportion of Brightest Voxels 100.0% Proportion of Brightest Voxels Brain Outline Brain outline Sagittal Mean sagttal SD Scale: Axial Coronal Corpus Corona sex: Sagittil Striatum Putarnen 2.85 276 283 2.74 285 291 2.83 Ansterior Putamen Anterior Putarnen posterior putamen 3 02 308 ltum Asymmetry Striatum Asymmetry 1.51 % 1.51 ± % 1-123 FP Modality NM 109.2 0.807 1.08 Slice 311'91 Slice 631129 Slice 31 '91 Slice 31M91 Caudate 325 Slice 41/10! Slice 41/109 313 export txport NM:07-Jul-2011 NM:07-Jul-2011 13:42:52 NM07„Ju1-2011 134252 posterior putamen Ansterior Putamen Ansterior putamen 2.91 0.52 3.08 3.02 b 3.055- 2.839 2.73 2.847 2876 2.793 Export 250% 3.76 % 1.51 % 376 % 376% 376 ± % Putamen 0.87 2.391 291 2.791 Database Settings 3.08 3.025 325 3.25 1.08 3.023 M 072Y Reset Striatal ROI Position Peset Striatal ROI Position *set Striatal ROI Position Posterior Putar1En 2 79 279 2.791 2.79 2.83 2873 2.76 2.87 ± 0.00 Fusion Controls BRAIN SPECT Asymmnetry Measures Asymnmetry Measures Ansterior Putamen Ansterior Putamnen Axial 3.02 3 02 Cortical Coroncal 2.56 Axial Coronal Coroncal Coronal Coronal SD Cortecal Proportion of Brightest Voxels 300.0% Putamen Asymrnetry Caudaten Asymmetry Putamen Asymmetry Pautaten Asymmetry 2.64 % 2.64 ± 0.00 % 2.764 ± 0.00 % 0.93 3.08 0.83 2.1 2.83 M 072M Left Right I ntormation: Asymmetry Measures Asymrnetry Measures Slice 31M Slice 31391 Slice 531129 Slice 61/129 Slice 41/109 Slice 31/65 Slice 13236 Slice 46191 Slice 531129 W:07-JU-2011 134252 134202 13:42:52 13:42 52 1342:S2 W:07-JU-2011 134252 Slice Reset Striatal ROI Position Axial Ansterior Putamen Coronal 2.73 276 Findings Navigator Modality Radiopharmaceutical Slice Slice 41/109 Slice 41 91 Slice Slice 411109 1 10be Slice 1342:52 134282 Putamen Asymmetry Delete 161 % Slice 40109 Slice 61129 Slice 61/129 134252 134252 Link Len and Rignt ROI Editing Link Len and R'gnt ROI for Editing _ DaTSCAN2 Link Len and Rignt ROI ror Editing Link Len and Right ROI tor Editing Striatal Values displayed are CNTS 2.86 2.83 2.25 2.79 Slice Slice 531129 Slice 13236 Putamen (L) / caudate (L) Putamen (L) c Caudate (L) 1342:52 0.87 ± o_oo c_oo Striatum Asymmetry putamen Asymmetry Sutriatum Asymmetry 1.51 % 1.15% 1.42 % "Functionality") may not (yet) be commercially available in your country. Due to regulatory requirements, Sceniurn DaTSCAN2 • Scenin_DaTSCAN2 scenium DaTSCAN2 Scale: scale: 0.62 ov: 16.8x20.8crn scale: 0.62 ov: scale: ov: scale: 0.62 fov: 16.9x20.8cmn scale: FOV: 0.62 ov: 1 0.621 ov: 0.62 ov: 0.62 f ov: Sceniurn DaTSCAN2 . scenium_oaTSCAN2 Sceniumn DaTSCAN2 ium_OaTSCAN2 Scale: scale: 0.62 fov: 16.gx20.8cm 0.62 fov: 16.9x20.8cm 0.5 FOV: 21.2x26.2cm 0.62 fov: 16.9x20.8cmn 0.62 fov: 16.8x20.8crn 0.5 FoV: 21.1x26.2cm 0.62 fou: 16.9x20.8cm 0.621 fov: 16.8x20.8crn Asymmetry Measures Asynvnetry Measures Patient Values Caudate Asymmetry Caudate Asymmetry' Caudaten Asymmetry 3.76 % 376 % Display Stnatal Box Display Stniatal Box S TS CAN2 S T S S TS Proportion of Brightest Voxels 100.0% 1-123 FP Graph Reset Striatal ROI Position Link Len and Right ROI ror Editing 279 273 1342:S2 NM: W 145.6 L 109.2 109.2 M 072M 109. 109.2 M072Y NM: W 145.6 L 109.2 M NM:W145.6L 109.2 M NM:W146.6L 109.2 - NM: W 145.6 L 109.2 NM: W 146.6 L 109.2 M NM:W 145.6 L 109.2 M072Y 267 % 376 % 3.76 % Database: Test Database Nonnalization region: Occipital lobe Normalization region: Occipital lobe Normnalization region: Occipital lobe Clobe lobe Striatum Asymmrnetry Putamen Asymmetry Putamen Asynvnetry Caudate Asymmetry' •triatal Striatum Striatum Asymmetry 264 % 264% 1.51 % lobe sceruum_DaTSCAN2 Database: Test Database ( Ratio to Normalization Region Display Striatal BOX -p NM: W 145.6 L IOS 'lay Stnatal BOX TSCAN2 TSCA putamen Asymmetry 3.76 % 2.64 % 1.51 % OK 1.51 % Link Lent and Rignt ROI ror Editing Database: Database Graph Putamnen (L) / Caudate (L) Putamen (L) / Caudate (L) Putamen (L) 1 Caudate (L) 1-123FP 1-123 FP 1-123 FP M 1-123 FP 1-123FP Ml-123ÉP . Please ensure that the patient radiopharmaceutical matches the selected nce ( Striatum Asymmnetry 3.08 Normalization Region Normalization region: Occipital lobe Normalization Region: Occip M 072M M072Y 0.83 Scale: Striatum Asymmetry Patient Values 1-123FP M 1-123 FP 1-123 FP ert to Automatic Fus•on Calculated on Irst Loading zoom Putarnen (R) I Caudate (R) Caudate Asymmnetry 0.87 Patient VE Ratio and asymmetry calculated using mean ot the brightest 75% ot voxels in Close Normalization region: Occip Normalization Region: Normalization Region: Oct Display Striatal Box 1.0 3.04 Putamen Asymnmetry Caudate Asymmetry Caudaten Asymmetry pautaten Asymmetry Ratio to Normalization Region Link Len and Rignt ROI ror Editing Link Len and Rignt ROI Editing rform Automatic Fusion Based on Functional Data Antenor Putamen 1762 NM: L 109.2 Axial tion Region 1l-123FP 1-123 FP Ml-123ÉP Asymmetry Measures ScenüT._DaTSCAN2 3.08 local Siemens Healthineers sales representative for the most current information. Putarnen (R) / Caudate (R) Putamnen (L) / Caudate (L) Putarnen (R) J' Caudate (R) Putamnen (L) /' Caudate (L) Putamnen (R) / Caudate (R) Putamnen Asymmetry 0.53 0.93 Copyright O Siemens Healthcare GmbH, 2018 2.81 3.76 % 2.64 % 1.51 % 3.76 % 161 % 308 Striatal regions. Striatal Analysis Striatal 1-123FP Ratio to Normalization Region Normalization Region Caudate Display Striatal Box Left Right Findings Navigator Ratio and asymmetry calculated using mean ot the brightest 75% ot voxels in Ratio and asymmetry calculated using mean 0t the brightest 75% 0t voxels in Tools Import 4.0 Left Reset Striatal ROI Position Putamen (L) / Caudate (L) Putamen (R) / Caudate (R) Putamen (L) caudate (L) -t Findings Left Normalization Region Ratio to Normalization Region Ratio to Normalization Rego 1762 3.76 % 376% Axial 0.93 Striatal regions. Striatal Analysis Caudate.. Create Caudate___ Credate_. Link Lett and Right ROI for Editing NM07-Jul-2011 134252 Ratio to Normalization 2_64 % Striatum Striatal 3 08 308 3.025 3.04 3.02 3.08 3.17 304 3 08 3_13 M 1-123 FP Ratio and asymmetry calculated using mean of the brightest 75% ot voxels in Ratio and asymmetry calculated using mean ot the brightest 75% ot voxels in 0.87 13:4252 putamen Asymmetry Putamen Asymmetry Caudate Asymmetry Caudaten Asymmetry Stratum Asymmetry Sautatem Asymmetry putaren Asymmetry 264 % 2.64 % 161 % 0.87 Striatum Slice 46191 Slice 461 91 Slice 61/129 Display Striatal Box Slice Reset value Value M 072M 134252 Striatal regions. Findings Navigator Close Putamen Credate Caudate.. Caudate 325 3_13 Scale: Loes Reset Striatum pautaten Asymmetry Cancel Putamen (L) / Caudate (L) Putamen (R) / Caudate (R) Putamnen (L) / Caudate (L) Caudate 13:42:52 325 Putamen Striatal H de H de L Reset NM: W 145.6 L 109.2 Putamen 2.834 2.86 2.839 2.83 1.51 2.83 2.791 2.912 2.26 0.91 Snapshot Neuro . Neuro. Reset Strjatal ROI Position - Scenium_DaTSCÅN2 0.62 Striatal regions. Display Striatal Box Ansterior putamen Caudate.. 10 1.0 OK cancel Striatal Analysis 0.93 3.08 3.04 0.91 Putamen 2.83 283 Caudate Caudate. Ansterior Putamen Posterior Putamen Anterior Putarnen 3.04 Caudate Asymmetry Slice Neuro _ 40 40 60 NM07-Jul-2011 Striatal Graph Scale: 0.62 1-123 value Source 2 86 Axial Neuro.. Ansterior Putamen Ansterior Putamnen 2.59 276 Credate Create Cancel Ratio and asymmetry calculated using mean ot the brightest 75% ot voxels in copy Export Results Putamen Ratio and asymmetry calculated using mean 0t the brightest 75% 0t n 0t the brightest 75% 0t brightest 75% 0t Reset stnatal ROI position Reset Striatal ROI Position Reset stniatal ROI position Posterior Putamen posterior putamen 2.791 1.59 2.76 2_79 1.51 % 264 ± Putamen Asymmetry Anterior Putarnen M 072Y patient Age Snapshot Neuro _ Neuro. Caudate Slice - Scenium DaTSCAl Slice 31/65 Slice 31/'91 Slice 411109 Slice 31191 Findings Navigator NM07X-2011 1342:S2 279 1342:S2 Peset Striatal ROI Position Reset Striatal ROI Position Ansterior Putamen Snapshot Neuro... Striatal regions. Striatal Analysis Striatal regions Tools OK Edit Asymmetry Measures Corpys Asymmnetry Measures Caudate Asymrnetry Copy Export Results Posterior Putamnen Posterior Putamen Ansterior Putarnen Snapshot Putamen (L) / Caudate (L) txport Asymmetry Measures Neuro Cancel Close Axial - Scenium DaTSCAN2 1-123 FP 0.93 IS Snapshot Neuro.. Neuro... Graph Link Left and Right ROI for Editing Link Lent and Rignt ROI for Editing Link Left and Rlght ROI for Editing Link and Right ROI tor Editing AsymnEtry Measures Putamen Asyrnmetry .4 Striatum Asymmetry Caudate Asymmetry Snapshot Values displayed are CNTS Sutriatum Asymmetry Sautatem Asymmetry 1.51 % 3.76 % 2.64 % Striatum Asymmetry Caudaten Asymmetry Putamen Asymmetry NM: W 145.6 L 109.2 M072Y Asymmetry Measures 13:42:52 13:42 52 134252 Slice Slice 31M Link Lett and Right ROI tor Editing Link Lent and Rignt ROI ror Editing Slice 32365 Slice Slice 46191 Slice 33'65 Slice 32/65 Slice 13236 Slice 631/129 Slice 53'12g Slice 61/129 Slice 531129 Slice 531/129 Slice 431/129 Slice Slice 5311291 Slice 74/128 Slice 73/129 Slice 61/129 values displayed are CNTS Display Striatal Box M072Y 161 % DaTSCAN2 Striatum Asymmetry Caudate Asymmetry LA Caudaten Asymmetry Caudate Asymmetry Caudate Asymmnetry Caudate Asymrnetry 376% 3.76 % 176% Putamen Asymmetry 146 PM 1:46 2:02 PU 201 PU 189 PU Striatum Asymmnetry Stnatum Asymmetry Putaten Asymmetry Stratum Asymmetry Loading patient data._ 12:48 PM 2:20 PM 129 PM 1:45 PM PM Reset e Lines Reset