This Job Aid will describe the benefits of  RESOLVE

VB19B RESOLVE Job Aid RESOLVE RESOLVE is a magnetic resonance imaging (MRI) measurement technique and stands for Readout Segmentation of Long Variable Echo-trains. With the RESOLVE method, a readout-segmented, multi-shot diffusion-weighted imaging se- quence is used which provides an improved image quality compared to standard-single-shot echo-planar imaging (ss-EPI) (see image below). RESOLVE Conventional single shot epi 1st shot 2nd shot 3rd shot 4th shot 5th shot Single shot Long TE Long Echo Spacing Phase-encode direction (kv) Readout direction (kx) k-space trajectory k-space trajectory RESOLVE supports all the standard acquisition and data processing features for diffusion- weighted imaging (DWI) and diffusion tensor imaging (DTI). The RESOLVE method: • Delivers high resolution DWI with less distortion and less susceptibility in regions prone to artifacts • Enables evaluation of smaller lesions and supports increased diagnostic confidence • Enables high resolution DTI of the brain, spine, breast and prostate. Page 1 HRT HOOD05162002642559 8-7-2017 SIEMENS Healthineers VB19B RESOLVE Job Aid Benefits of RESOLVE RESOLVE uses the same diffusion preparation as single-shot EPI, however, the k-space trajectory is di- vided into multiple segments in the readout direction. This leads to a reduction of TE and encoding-time as well as an increase of image quality. In addition, the 2D phase navigator allows motion correction. A Single Shot + k-space Conventional DWI B 1 Shot 2 Shot 3 h 4 5th Shot N + W E S k-space Navigator RESOLVE In summary, RESOLVE provides the following benefits: • Insensitivity to motion-induced phase errors • Reduced SAR in comparison to TSE-based methods • iPAT compatible for faster scans and further reduced distortions • Reduced susceptibility (especially for metal implants*) and blurring artifacts • High-resolution within DWI and DTI Page 2 HRT HOOD05162002642559 8-7-2017 VB19B RESOLVE Job Aid RESOLVE for brain diffusion – Significant metal* artifact reduction for DWI EPI b0 EPI b1000 EPI ADC conventional conventional conventional RESOLVE b0 RESOLVE b1000 RESOLVE ADC Source: Tongji Hospital, Wuhan, China *The MRI restrictions (if any) of the metal implant must be considered prior to patient undergoing MRI exam. MR imaging of patients with metallic implants brings specific risks. However, certain implants are approved by the governing regulatory bodies to be MR conditionally safe. For such implants, the previously mentioned warning may not be applicable. Please contact the implant manufacturer for the specific conditional information. The conditions for MR safety are the responsibility of the implant manufacturer, not of Siemens. Page 3 HRT HOOD05162002642559 8-7-2017 SIEMENS Healthineers VB19B RESOLVE Job Aid RESOLVE – Anatomy-true, high resolution DWI EPI conventional RESOLVE Source: Nagoya University School of Medicine, Japan Interested in more information about RESOLVE? Please find some references stated below: Publication Head and Neck region Koyasu, Sho, et al. The clinical utility of reduced-distortion readout-segmented echo-planar imaging in the head and neck region: initial experience. European Radiology 24 (12) 2014; 3088-3096. Publications Spine region Cohen-Adad, Julien. High-Resolution DWI in Brain and Spinal Cord with syngo RESOLVE. MAGNETOM Flash 50 (2) 2012; 16-22. Hayes, Laura L. et al. RESOLVE: A Powerful Tool for Imaging the Pediatric Spine. MAGNETOM Flash 57 (2) 2014; 38-45. Page 4 HRT HOOD05162002642559 8-7-2017 VB19B RESOLVE Job Aid Excurse: Diffusion-weighted imaging and beyond The following table includes more information about the basic technologies lying beyond RESOLVE. Imaging Explanation Diffusion-tensor imag- Diffusion-tensor imaging (DTI) is a method for displaying the directional dependency ing (DTI) of diffusion. The method is applied for examinations involving the architecture, con- figuration, and integrity of nerve fiber bundles (neurological research). Diffusion tensor is the physical magnitude which takes into account the directional dependency of diffusion. The diffusion tensor indicates the mobility of water mole- cules in all three coordinates. The tensor data are used as the basis for computing additional maps or diffusion tractography. Diffusion-weighted Diffusion-weighted imaging (DWI) is a MR application. In general, MR imaging is imaging (DWI) sensitive to motion and flow to the relatively low diffusion effect (visualized with strong gradients). Diffusive movements in tissue (for example: natural diffusion of water) reduce the signal. Therefore, regions are of interest where diffusion is reduced compared with its surroundings (such as cell membranes along white matter tracts, or in areas of the brain affected by stroke). Reduced diffusion means the reduction in signal is less intense: the affected regions are displayed brighter in the diffusion- weighted image. DWI is a valuable biomarker to define target volumes for dose escalation in radia- tion therapy for instance for prostate cancer. Echo-planar imaging Echo-planar imaging (EPI) is a "single-shot" method. Shortly said, it means that to (EPI) acquire an entire image one "shot" is needed. Therefore, an EPI sequence uses a sin- gle excitation pulse to acquire an entire image, i.e. the whole 2D plane by generating an echo train of a sufficient number of gradient echoes to fill the raw data matrix. Page 5 HRT HOOD05162002642559 8-7-2017 SIEMENS Healthineers Please note that the learning material is for training purposes only! For the proper use of the software or hardware, please always use the Operator Manual issued by Siemens. This material is to be used as training material only and shall by no means substitute the Operator Manual. Any material used in this training will not be updated on a regular basis and does not necessarily reflect the latest version of the software and hardware available at the time of the training. The Operator's Manual shall be used as your main reference, in particular for relevant safety information like warnings and cautions. Note: Some functions shown in this video are optional and might not be part of your system. The information in this video contains general technical descriptions of specifications and options as well as standard and optional features that do not always have to be present in individual cases. Functionalities described in the material or parts of this functionality may not yet be released for customers and not yet be commercially available in every country. Due to regulatory requirements, the future availability of said function- alities or parts thereof in any specific country is not guaranteed. Please contact your local Siemens sales representative for the most current information. The reproduction, transmission or distribution of this training or its contents is not permitted without express written authority. Offenders will be liable for damages. All rights, including rights created by patent grant or registration of a utility model or design, are reserved. 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