MR Tissue 4D Numaris X

BMR MR Tissue 4D Numaris X The MR Tissue 4D is used in Dynamic Contrast Imaging to characterize the properties of the con- trast agent passage through the tissue. Parametric maps are calculated based on a Volume of Interest and permit the user to generate findings on specific regions of interest using Tissue 4D tools. 1. From the Patient Browser, load the appropriate data set into the MR Tissue 4D Workflow  If the examination has been correctly mapped, double click to load.  If manual mapping is required, right-click the examination and select Assign Workflow > MR Tissue 4D 2. Motion Correction Step is used to verify the automatic alignment of the dynamic data set to a defined reference volume A. Select > Motion Correction Icon to toggle between the motion corrected and non-motion corrected series B. Blended slider > move the slider to the required time point > select the confirm icon to confirm new reference point Note: Can exclude time points by moving the slider to the required time point; select the Exclude Phase icon, the selected phase turns red or Exclude Rest All icon which excludes all time points after the selected time point. MR Tissue4D Analysis 50.36s Motion Correction Blending 100% O Set As Toggle Exclude Exclude Referen. Images Phase Rest All SIEMENS Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2018 Healthineers Job Aid | MR Tissue 4D Numaris X Effective Date: 01/03/2019 | HOOD05162002979863 3. Alignment Step is used to verify the automatic alignment of the pre-contrast and morphology series to the dynamic series A. Aligning morphological and dynamic data o Check automatic alignment o If necessary, select another Morphology data set from the list oUse the Blending slider to evaluate visually the quality of the selected morpholog- ical data with the dynamic volume o If necessary, you can toggle between the aligned and non-aligned data by selecting this Toggle Images icon. You can distinguish aligned and non-aligned images by the series name which is displayed in the image text. Blending 100% O Toggle Images B. Aligning pre-contrast and dynamic data o Check automatic alignment o If required select a Flip Angle or measured T1 map from the list oUse the Blending slider to evaluate visually the quality of the selected pre-contrast data with the dynamic volume o If necessary, you can toggle between the aligned and non-aligned data by selecting this Toggle Images icon. You can distinguish aligned and non-aligned images by the series name which is displayed in the image text. Alignment Pre-contrast To Dynamic Flip Angle 30 Blending 0 100% Aller 4. Processing Step is used to verify or modify the result of the pharmacokinetic modeling within a specific volume of interest or to define a new volume of interest and to start a new evaluation. You may choose between two models: Tofts model or Qualitative model. Note: Qualitative model is used to calculate the contrast medium concentration. Tofts model is used to evaluate the quantitative blood flow of the tissue. A. In the image segment, check the predefined VOI B. If necessary, choose the VOI tool from the upper right corner menu to draw a new VOI ... Volume 743.04 cm3 TISSUE 4D Min / Max 6.00 /624.00 ROI Circle Mean/SD: 148.23 /50.90 1/1/1980, M. 26Y Marker CURRENT 1/5/2006 Arrow 11_vibe_MOCO latest Phase_14 Angle CurrentMR_T4D_DYNAMIC_MOCO-01.013 6:12:34 PM VOI Sphere 1019 IMAna VOI Freehand VOI Sphere MR Segmentation Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2018 Page 2 of 5 Job Aid | MR Tissue 4D Numaris X Effective Date: 01/03/2019 | HOOD05162002979863 C. In the Case Navigator, select the pharmacokinetic Model (i.e. Tofts or Qualitative) from the list o If you selected the Tofts model from the list, the AIF selection list is displayed oAIF Selection: choose Fast, Intermediate, or Slow that provides applicable information about the concentration of the contrast agent in the blood Processing Model Tofts AIF Intermediate Contrast Agent Fast Sele Intermediate Protocol Slow oNote: Select the Settings icon if you want to adjust the settings for the selected Contrast Agent and the Protocol.  The MR Tissue 4D Processing Settings dialog box opens. Adjust the set- tings for the Contrast Agent and the Protocol. Select OK. MR Tissue4D Processing Settings ? X Contrast Agent Magnevist Field Strength 3T Gadovist Prohance Relaxivity I/mmol/s Multihance Molarity 1.5 mmol/ml Dotarem Omniscan Dose 0.1 mmol/kg Optimark Volume 10 ml Protocol Qualitative Tofts Protocol Type Pixelwise T1 Threshold 20 OK Cancel Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2018 Page 3 of 5 Job Aid | MR Tissue 4D Numaris X Effective Date: 01/03/2019 | HOOD05162002979863 o Select the Arrival Time icon to display the arrival time bar in the upper right segment o Manipulate the time bar to adjust the arrival time o Select the Calculate Maps icon to start calculation of the parametric maps Processing Recalculation is required Model Qualitative Contrast Agent Magnevist Protocol Constant T1 Conings LL 65.47 sec Mage 5. The Reading Step is used to evaluate the created maps and to create findings A. Go through images and mark relevant areas using the tools from the upper right corner menu or use the icons in the Reading step. The result for the marked area is displayed be- low the graph. For each drawn ROI or VOI, a finding is automatically created and listed in the Findings Navigator. B. If required, select another parametric map from the lower left corner menu. Reading Expor to Freshand 6. The Viewing Step is used for viewing images Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2018 Page 4 of 5 Job Aid | MR Tissue 4D Numaris X Effective Date: 01/03/2019 | HOOD05162002979863 Please note that the learning material is for training purposes only! For the proper use of the software or hardware, please always use the Operator Manual or Instruc- tions for Use (hereinafter collectively “Operator Manual”) issued by Siemens Healthineers. This material is to be used as training material only and shall by no means substitute the Operator Manual. Any material used in this training will not be updated on a regular basis and does not necessarily reflect the latest version of the software and hardware available at the time of the training. The Operator's Manual shall be used as your main reference, in particular for relevant safety information like warnings and cautions. Note: Some functions shown in this material are optional and might not be part of your system. Certain products, product related claims or functionalities (hereinafter collectively “Functionality”) may not (yet) be commercially available in your country. Due to regulatory requirements, the future availability of said Functionalities in any specific country is not guaranteed. Please contact your local Siemens Healthineers sales representative for the most current information. The reproduction, transmission or distribution of this training or its contents is not permitted without express written authority. Offenders will be liable for damages. All names and data of patients, parameters and configuration dependent designations are fictional and examples only. All rights, including rights created by patent grant or registration of a utility model or design, are reserved. Copyright © Siemens Healthcare GmbH 2018 ………………………………………………………… Siemens Healthineers Headquarters Siemens Healthcare GmbH Henkestr. 127 91052 Erlangen, Germany Telephone: +49 9131 84-0 siemens.com/healthineers Published by Siemens Healthcare GmbH © Siemens Healthcare GmbH, 2018 Page 5 of 5