Atellica® IM Analyzer Hardware Overview Online Training

Welcome to the Atellica® IM Analyzer Hardware Overview Online Training course. The Atellica®  Solution consists of a family of modules and analyzers that are configurable for individual laboratory testing needs including: Central workstation/computer Sample entry module Analyzers (including immunoassay and chemistry technologies) This course will introduce you to the hardware components on the immunoassay analyzer. NOTE: Refer to the Atellica Solution Operator's Guide for information on safety precautions that should be followed when operating the system.   Upon successful completion of this course, you will be able to: Identify hardware components and their function Describe the test processing sequence Congratulations. You have completed the Atellica® IM Analyzer Hardware Overview online training course. Listed below are the key points that have been presented.  Take time to review the material before you proceed to the final quiz.  Identify the hardware components and their function Exterior Components System front and back cover - controlled by interlocks. Operator can unlock using a button in the software Sample tip loading lid - used to load additional packs of sample tips Cuvette bin lid - used to load additional cuvettes Reagent drawer - used to load up to 5 reagent packs at a time, and to remove empty reagent packs Solid waste area - used to remove cuvette waste, sample tip waste, and tip tray waste System fluid drawer - used to replace the IM Acid, IM Base, IM Wash, and IM Cleaner bottles Water and liquid waste area - contains one reservoir for water and three reservoirs for waste Fan filter - there is one fan filter located in the center rear panel Main power switch - used to power off and on the analyzer Interior Components Sample tip loader - maximum capacity of 1800 sample tips Wash ring - a circular track that washes and prepares reaction cuvettes for the chemiluminescent reaction. Also location of the acid probe Luminometer - contains the photomultiplier tube (PMT) with photon-counting electronics, base probe, and waste probe. Location where the chemiluminescent reaction occurs Cuvette bin - maximum capacity of 1500 cuvettes Reagent drawer - ability to load up to five primary/ancillary reagent packs at a time Reagent compartment - stores both primary and ancillary reagent packs in a single refrigerated tray. The temperature of the reagent compartment is maintained at 4 to 8 oC. The compartment can hold up to 42 primary reagent packs and 35 ancillary reagent packs Reagent probes - three reagent probes are used to deliver primary and ancillary reagent to the cuvettes.  The probes are washed after each dispense Incubation ring - a circular, insulated track comprised of 2 independently movable rings that advance the cuvettes to the sample and reagent positions. Temperature is maintained at 37 oC Sample probe - transfers sample from sample tube to a cuvette in the incubation ring Describe the test processing sequence Transfer of cuvettes from the cuvette bin to the incubation ring: The system takes the cuvettes from the cuvette loading bin via the conveyor At the top of the conveyor, cuvettes are positioned upright in the orientation chute Once a cuvette reaches the end of the orientation chute, it drops down the vertical chute into the cuvette channel assembly Cuvettes are moved through the cuvette channel assembly by the cuvette pusher and drop down into the incubation ring at the ring loader position. The system internal air temperature is controlled to 33 oC. The heaters used to control the internal air temperature also serve to pre-warm the cuvettes to 33 oC prior to the cuvettes entering the incubation ring. While in the incubator, the cuvettes are maintained at 37 oC The steps of the test processing sequence: Sample is transferred into the cuvette The sample probe first picks up a tip from the sample tip tray The sample probe then aspirates sample from the sample tube and transfers the sample into the cuvette in the incubation ring After dispensing, the tip is removed from the sample probe. The tip falls down the tip waste chute into the solid waste bin Primary and ancillary reagent are transferred into the cuvette. The primary reagent contains paramagnetic particles (PMPs) and Acridinium ester. The PMPs provide the solid phase of the chemiluminescent reaction, and the Acridinium ester provides the label that is used to determine the quantity of analyte in the sample. The ancillary reagents include diluents, pretreatments, and special washes. Ancillary reagents are not required for every test One of the reagents probes aspirates reagent from the reagent compartment The probe then dispenses the reagent into the cuvette in the incubation ring The cuvette incubates in the incubation ring for a time specified by the assay test. Longer incubation assays are transported to the inner incubation ring to complete their incubation, while shorter incubation assays stay in the outer incubation ring for the duration of their incubation. During incubation, the analyte being measured in the sample and the acridinium ester label are bound to the PMPs The PMPs in the cuvette are washed in the wash ring and acid is added Following incubation, the incubation ring elevates the cuvettes to the wash ring. The unbound sample and reagent are washed away from the PMPs in the cuvette in the wash ring. The wash fluid is heated to 34 oC as it is dispensed into the cuvette through the dispense ports. Magnets positioned along the wash ring pull the PMPs to the side of the cuvette. Aspirate probes then draw fluid out of the cuvette leaving the PMPs with the bound material behind. The number of wash cycles is determined by the assay test definition After the final wash, fluid is aspirated out of the cuvette and acid is added The cuvette is moved to the luminometer and base is added. The base reagent is heated to 34 oC as it is dispensed. The addition of the base to the cuvette changes the chemical environment to cause the chemiluminescent reaction to occur as the acridinium ester oxidizes The PMT takes the chemiluminescent measurement The PMT measures the light emitted as relative light units (RLUs) The system software converts the RLU raw signal into test results Liquid waste is removed from the cuvette The cuvette falls into the solid waste bin   The steps of the test processing sequence on the Atellica® IM Analyzer include: Sample is transferred into the cuvette Primary and ancillary reagent are transferred into the cuvette The cuvette incubates in the incubation ring The paramagnetic particles (PMPs) in the cuvette are washed in the wash ring Acid and base are dispensed into the cuvette The photomultiplier tube (PMT) takes the chemiluminescent measurement Liquid waste is removed from the cuvette The cuvette falls into the solid waste bin   Test Processing Sequence Learn about the test processing sequence Instructions:Flash File:/content/generator/Course_90015491/sim_Atellica_IM_TestProcessingSequence/sim_Atellica_IM_TestProcessingSequence.htmHTML5 File:/content/generator/Course_90015491/sim_Atellica_IM_TestProcessingSequence/index.htmlPDF File: Hardware components of the Atellica® IM Analyzer: Exterior Components Interior Components Sample tip loading lid Cuvette bin lid Reagent drawer Solid waste drawer System fluid drawer Water and liquid waste area Fan filter Main power switch Sample tip loader Wash ring Luminometer Cuvette bin Reagent compartment Reagent loader Reagent probes Incubation ring Sample probe NOTE: The front and back covers of the system are controlled by interlocks. The operator can unlock the covers using a button in the software.   Hardware Components Learn about the main hardware components Instructions:Flash File:/content/generator/Course_90015491/sim_Atellica_IM_HardwareOverview/sim_Atellica_IM_HardwareOverview.htmHTML5 File:/content/generator/Course_90015491/sim_Atellica_IM_HardwareOverview/index.htmlPDF File: Please note that the learning material is for training purposes only!   Any material used in this training will not be updated on a regular basis and may not necessarily reflect the latest version of the software available at the time of the training.   Certain products, product related claims or functionalities (hereinafter collectively “Functionality”) may not (yet) be commercially available in your country.  Due to regulatory requirements, the future availability of said Functionalities in any specific country is not guaranteed. Please contact your local Siemens Healthineers sales representative for the most current information.   The reproduction, transmission or distribution of this training or its contents is not permitted without express written authority. Offenders will be liable for damages.   All names and data of patients, parameters and configuration dependent designations are fictional and examples only.   All rights, including rights created by patent grant or registration of a utility model or design, are reserved.   Copyright © Siemens Healthcare GmbH 2018 Please proceed to taking the course assessment.